ChemicalBook > CAS DataBase List > Ginsenoside Rh2

Ginsenoside Rh2

Product Name
Ginsenoside Rh2
CAS No.
78214-33-2
Chemical Name
Ginsenoside Rh2
Synonyms
20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-
CBNumber
CB3728899
Molecular Formula
C36H62O8
Formula Weight
622.88
MOL File
78214-33-2.mol
More
Less

Ginsenoside Rh2 Property

Melting point:
139-144 °C
Boiling point:
726.4±60.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka
12.91±0.70(Predicted)
form 
Solid
color 
White
InChIKey
CKUVNOCSBYYHIS-IRFFNABBSA-N
LogP
5.620 (est)
CAS DataBase Reference
78214-33-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ5776539
HS Code 
29389090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
73658
Product name
Ginsenoside Rh2
Purity
analytical standard
Packaging
10mg
Price
$714
Updated
2024/03/01
Cayman Chemical
Product number
23390
Product name
Ginsenoside Rh2
Purity
≥98%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
23390
Product name
Ginsenoside Rh2
Purity
≥98%
Packaging
5mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
23390
Product name
Ginsenoside Rh2
Purity
≥98%
Packaging
10mg
Price
$286
Updated
2024/03/01
Cayman Chemical
Product number
23390
Product name
Ginsenoside Rh2
Purity
≥98%
Packaging
25mg
Price
$651
Updated
2024/03/01
More
Less

Ginsenoside Rh2 Chemical Properties,Usage,Production

Description

Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.

Chemical Properties

White solid

Uses

20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.

Definition

ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.

Biological Activity

Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].

Ginsenoside Rh2 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ginsenoside Rh2 Suppliers

China 231 Europe 2 Germany 2 India 1 Japan 1 United Kingdom 6 United States 29 Global 272
cfm Oskar Tropitzsch
Tel
--
Fax
--
Country
Germany
ProdList
1136
Advantage
62
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
More
Less

View Lastest Price from Ginsenoside Rh2 manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Ginsenoside Rh2 78214-33-2
Price
US $100.00-1000.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-06
Shanghai Standard Technology Co., Ltd.
Product
Ginsenoside Rh2 78214-33-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-27
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Ginsenoside Rh2 78214-33-2
Price
US $80.00/g
Min. Order
1mg
Purity
95%
Supply Ability
50kg
Release date
2020-03-04

78214-33-2, Ginsenoside Rh2Related Search:

Escin Ginsenoside Re Ginsenoside Rg1 GINSENOSIDE RE Ginsenoside Rd TRIBULOSIDE Ginseng extract Ginsenoside Rb1 ginsenoside Rh3 Panaxadiol Panaxatriol Ginsenoside Rc GINSENOSIDE RB2 GINSENOSIDE RH1,Ginsenoside Rh1 ,98% ginsenoside Rh(4) Ginsenoside-Rg5 Ginsenoside Rb3 GINSENOSIDE F2

  • b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl
  • (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside
  • Ginsenoside Rh2, 20(S)-
  • (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside
  • GINSENOSIDE RH2
  • dihydroxydammar-24-en-3-yl
  • β-D-Glucopyranoside, (3β,12β)-12,20-
  • R-form-Ginsenoside Rh2
  • 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside
  • 3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol
  • 3β-(β-D-Glucopyranosyl
  • GINSENOSIDE Rh2(SH)
  • Ginsenoside Rh2 ,98%
  • 20(S)-Rh2
  • Natural Plant Extracts Ginsenoside Rh2 HPLC 15% 50% 98% 78214-33-2
  • 2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
  • Ginsenoside Rh2 USP/EP/BP
  • (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • Ginsenoside Rk1&Rh2&Rg3
  • GINSENOSIDE Rh2 (S-FORM)(AS) 25mg
  • Ginsenoside Rh2-RM
  • Ginsenoside Rh2(AS)
  • Ginsenoside Rh2(P)
  • 10% Ginseng extract inclusion complex
  • 78214-33-2
  • C36H62O8
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
  • Ginsenoside series
  • 78214-33-2