ChemicalBook > CAS DataBase List > Dexamethasone palmitate

Dexamethasone palmitate

Product Name: Dexamethasone palmitate
CAS No.: 14899-36-6
Chemical Name: Dexamethasone palmitate
Synonyms: D01615;Lipotalon;Limethason;Limethasone;Limethason (tn);DXM-21-palmitate;DEXAMETHASOME PALMITATE;Dexamethasone palmitate;Dexamethasone-21-palmitate;Dexamethasone palmitate (jan)
CBNumber: CB41074390
Molecular Formula: C38H59FO6
Formula Weight: 630.87
MOL File: 14899-36-6.mol

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Dexamethasone palmitate Property

Melting point:: 60-65 °C
Boiling point:: 710.1±60.0 °C(Predicted)
Density: 1.12
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 11.99±0.70(Predicted)
color: White to Pale Yellow
Stability:: Hygroscopic
InChIKey: WDPYZTKOEFDTCU-CDUXOLGFNA-N
SMILES: [C@@]12([H])C[C@@H](C)[C@](O)(C(=O)COC(=O)CCCCCCCCCCCCCCC)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H] |&1:0,3,5,28,31,33,35,45,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D298830
Product name: Dexamethasone21-Palmitate
Packaging: 250mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-0102469
Product name: Dexamethasonepalmitate
Purity: >98.0%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0102469
Product name: Dexamethasonepalmitate
Purity: >98.0%
Packaging: 10mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21400
Product name: Dexamethasone 21-palmitate
Packaging: 25mg
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-0102469
Product name: Dexamethasonepalmitate
Purity: >98.0%
Packaging: 50mg
Price: $170
Updated: 2021/12/16

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Dexamethasone palmitate Chemical Properties,Usage,Production

Description

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).

Chemical Properties

Colourless Thick Oil

Uses

A corticosteroid prodrug for the treatment of eye disorders.

Definition

ChEBI: Dexamethasone palmitate is an organic molecular entity.

Biochem/physiol Actions

Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.

Dexamethasone palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dexamethasone palmitate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Dexamethasone palmitate 14899-36-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000
Release date: 2023-07-27

Shaanxi Dideu New Materials Co. Ltd

Product: Dexamethasone palmitate 14899-36-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-02

Hubei Harvest Chemical CO.,Ltd

Product: Dexamethasone palmitate 14899-36-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000000000
Release date: 2022-12-23

14899-36-6, Dexamethasone palmitateRelated Search:

Palmitic acid 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate Dexamethasone-17-acetate Dexamethasone sodium phosphate Ascorbyl Palmitate Dexamethasone Palmitic anhydride hexadecanal Dexamethasone 21-phosphate disodium salt 6-hydroxydexamethasone PSXDNQUHAFMVPT-NWQAGDSVSA-N Dexamethasone 21-Propionate 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate) 16-beta Methyl Epoxide 16α-Methyl-11-oxo Prednisolone (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-Methylpregna-1,4-diene-3,20-dione Dexamethasone-d5 17,21-dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione

(11β,16α)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione

DEXAMETHASOME PALMITATE

Palmitic acid, 21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (8CI)

Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11β,16α)-

Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-palmitate (6CI, 8CI)

9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-palmitate

Dexamethasone palmitate

21-(Palmitoyloxy)-9α-fluoro-11β,17α-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione

D01615

Dexamethasone palmitate (jan)

Limethason (tn)

Dexamethasone Impurity 20（Dexamethasone Palmitate）

Dexamethasone Impurity 21（Dexamethasone Palmitate）

Dexamethasone-21-palmitate

DXM-21-palmitate

Limethason

Limethasone

Lipotalon

Dexamethasone palmitate (DXP)

21-Dehydrodexamethasone Dihydrate

Dexamethasone Palmitate Corticosteroid Raw Powder

lipophilic,prodrug,RAW 264.7,VEGF,Dexamethasone palmitate,Dexamethasone,Inhibitor,inflammation,inhibit,cytokine

2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl Palmitate

Dexamethasone Impurity 20 CRS（Dexamethasone Palmitate CRS）

Dexamethasone palmitate, 10 mM in DMSO

14899-36-6

C38H59FO6

Drug Analogues

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids