Dexamethasone palmitate
- Product Name
- Dexamethasone palmitate
- CAS No.
- 14899-36-6
- Chemical Name
- Dexamethasone palmitate
- Synonyms
- D01615;Lipotalon;Limethason;Limethasone;Limethason (tn);DXM-21-palmitate;DEXAMETHASOME PALMITATE;Dexamethasone palmitate;Dexamethasone-21-palmitate;Dexamethasone palmitate (jan)
- CBNumber
- CB41074390
- Molecular Formula
- C38H59FO6
- Formula Weight
- 630.87
- MOL File
- 14899-36-6.mol
Dexamethasone palmitate Property
- Melting point:
- 60-65 °C
- Boiling point:
- 710.1±60.0 °C(Predicted)
- Density
- 1.12
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 11.99±0.70(Predicted)
- color
- White to Pale Yellow
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D298830
- Product name
- Dexamethasone21-Palmitate
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- FD21400
- Product name
- Dexamethasone 21-palmitate
- Packaging
- 250mg
- Price
- $700
- Updated
- 2021/12/16
- Product number
- API0012845
- Product name
- DEXAMETHASONE PALMITATE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $721.88
- Updated
- 2021/12/16
- Product number
- FD21400
- Product name
- Dexamethasone 21-palmitate
- Packaging
- 500mg
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- API0012845
- Product name
- DEXAMETHASONE PALMITATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1732.5
- Updated
- 2021/12/16
Dexamethasone palmitate Chemical Properties,Usage,Production
Description
Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).
Chemical Properties
Colourless Thick Oil
Uses
A corticosteroid prodrug for the treatment of eye disorders.
Definition
ChEBI: Dexamethasone palmitate is an organic molecular entity.
Biochem/physiol Actions
Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.
Dexamethasone palmitate Preparation Products And Raw materials
Raw materials
Preparation Products
Dexamethasone palmitate Suppliers
View Lastest Price from Dexamethasone palmitate manufacturers
- Product
- Dexamethasone palmitate 14899-36-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2023-07-27
- Product
- Dexamethasone palmitate 14899-36-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000000000
- Release date
- 2022-12-23
- Product
- Dexamethasone palmitate 14899-36-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25