HEXAHYDROCURCUMIN

Product Name: HEXAHYDROCURCUMIN
CAS No.: 36062-05-2
Chemical Name: HEXAHYDROCURCUMIN
Synonyms: HEXAHYDROCURCUMIN;Hexahydrocurcumin-RM;Hexahydrocurcumin, BR;5-dimethyl ether Gallic Acid;5-dimethoxy-4-hydroxy Benzoic Acid;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one;1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one;3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-
CBNumber: CB41412369
Molecular Formula: C21H26O6
Formula Weight: 374.43
MOL File: 36062-05-2.mol

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HEXAHYDROCURCUMIN Property

Melting point:: 80-82℃
Boiling point:: 622.6±55.0 °C(Predicted)
Density: 1.226
Flash point:: 218℃
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly), DCM, DMSO
form: Solid
pka: 10.02±0.20(Predicted)
color: Pale Yellow
BRN: 2486876

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB01366
Product name: Hexahydrocurcumin
Purity: ≥95% (HPLC)
Packaging: 1MG
Price: $124
Updated: 2024/03/01

Sigma-Aldrich

Product number: SMB01366
Product name: Hexahydrocurcumin
Purity: ≥95% (HPLC)
Packaging: 10MG
Price: $744
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL82559
Product name: Hexahydrocurcumin
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $975
Updated: 2024/03/01

Sigma-Aldrich

Product number: 69727
Product name: Hexahydrocurcumin
Purity: analytical standard
Packaging: 10mg
Price: $835
Updated: 2024/03/01

Cayman Chemical

Product number: 11714
Product name: Hexahydrocurcumin
Purity: ≥95%
Packaging: 1mg
Price: $86
Updated: 2024/03/01

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HEXAHYDROCURCUMIN Chemical Properties,Usage,Production

Description

Hexahydrocurcumin is a natural product and glucuronide metabolite of curcumin that has anti-inflammatory, antioxidant, and anticancer properties. It reduces prostaglandin E₂ (PGE₂) production stimulated by phorbol 12-myristate 13-acetate (PMA; ) by 37% in human colonic epithelial cells when used at a concentration of 20 μM. Hexahydrocurcumin (3.125-25 μM) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner. It does not affect LPS-induced cytokine release but inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation when used at a concentration of 50 μM. Hexahydrocurcumin prevents the formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer and potentiates the effect of 5-fluorouracil .

Uses

Hexahydrocurcumin is an intermediate in the synthesis of Gingerenone A (G387500) which is an antifungal and antiparasitic diarylheptenone that is isolated from Zingiber officinale (more commonly known as ginger), a medicinal plant that is used to treat inflammation and musculoskeletal disorders.

Definition

ChEBI: Hexahydrocurcumin is a diarylheptanoid.

target

PGE | NOS | COX

HEXAHYDROCURCUMIN Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXAHYDROCURCUMIN Suppliers

China 114 India 1 United States 9 Global 124

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

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Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Cayman Chemical Company

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Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Riedel-de Haen AG

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Country: United States
ProdList: 6773
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View Lastest Price from HEXAHYDROCURCUMIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Hexahydrocurcumin 36062-05-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-09

Henan Aochuang Chemical Co.,Ltd.

Product: HEXAHYDROCURCUMIN 36062-05-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

36062-05-2, HEXAHYDROCURCUMINRelated Search:

Phosphorus pentachloride CHEBULAE FRUCTUS IMMATURUS DEMETHOXYCURCUMIN BIS(4-HYDROXYCINNAMOYL)METHANE 5"-MethoxyhexahydrocurcuMin (3S,5S)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTANE-3,5-DIOL FLLL31 DihydrocurcuMin Curcumin ASC-J9 Tetrahydrocurcumin TetrahydrocucuMin Hexahydropyridazin

HEXAHYDROCURCUMIN

5-Hydroxy-1-(4-hydroxy-3-Methoxycyclohexyl)-7-(4-hydroxy-3-Methoxyphenyl)heptan-3-one

(RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone

1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone

1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one

5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone

Hexahydrocurcumin, BR

3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-

5-dimethoxy-4-hydroxy Benzoic Acid

5-dimethyl ether Gallic Acid

5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one

Hexahydrocurcumin-RM

36062-05-2