AMINOPEPTIDASE M
- Product Name
- AMINOPEPTIDASE M
- CAS No.
- 9054-63-1
- Chemical Name
- AMINOPEPTIDASE M
- Synonyms
- LAP;CRP2;TCF5;AP-M;LMO5;SmLIM;IL6DBP;TGF-β1;hTGF-β1;MGC32080
- CBNumber
- CB4166931
- Molecular Formula
- C12H24O2
- Formula Weight
- 0
- MOL File
- Mol file
AMINOPEPTIDASE M Property
- storage temp.
- 2-8°C
- form
- powder
- color
- white
- biological source
- Porcine kidney
- Water Solubility
- physiological buffer: soluble
water: soluble - Specific Activity
- 10-40units/mg protein (Bradford)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- L6007
- Product name
- Leucine Aminopeptidase, microsomal from porcine kidney
- Purity
- Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
- Packaging
- 25units
- Price
- $567
- Updated
- 2025/07/31
- Product number
- SRP0300
- Product name
- TGF-β1 Latent human
- Purity
- recombinant, expressed in FreeStyle? 293-F cells, ≥98% (SDS-PAGE)
- Packaging
- 5μg
- Price
- $315
- Updated
- 2025/07/31
- Product number
- L6007
- Product name
- Leucine Aminopeptidase, microsomal from porcine kidney
- Purity
- Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
- Packaging
- 50units
- Price
- $887
- Updated
- 2025/07/31
- Product number
- L6007
- Product name
- Leucine Aminopeptidase, microsomal from porcine kidney
- Purity
- Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
- Packaging
- 100units
- Price
- $1620
- Updated
- 2025/07/31
- Product number
- T7039
- Product name
- Transforming Growth Factor-β1 human
- Purity
- TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture
- Packaging
- 2 μg
- Price
- $347
- Updated
- 2025/07/31
AMINOPEPTIDASE M Chemical Properties,Usage,Production
Chemical Properties
Red lyophilized powder, red-brown liquid or suspension, soluble in water, optimal pH 7.5-9.0.Stability: suspension of cattle containing magnesium sulfate or magnesium chloride as a stabilizer; 4 ℃, pH value of about 8 when stored for 6 months unchanged vitality; lyophilized powder can be stabilized at 4 ℃ for several months. Inhibitors include heavy metal ions, EDTA, citrate; activators include manganese chloride (3-4 mmol/L), Mg2+. Enzyme reaction: aminoacylated peptide + H2O═ amino acid + peptide.
Uses
Transforming Growth Factor-β1 (TGF-β) human has been used :
- to study the expression of PDGFRB (Platelet derived growth factor receptor β) in association with transforming growth factor-β signaling.
- to stimulate lung fibrosis in human fetal lung fibroblast cell line in order to further measure the in-plane elasticity of live cell layers using a pressure sensor embedded microfluidic device.
- to study the effect of TGF-β on HTRA1 (high-temperature requirement A1)-affected Wnt target genes.
Uses
Leucine Aminopeptidase, microsomal from porcine kidney has been used in aminopeptidase N (APN) inhibitor screening assay in adenocarcinoma cell line ES-2 and in the inhibition kinetic studies with APN inhibitor.
General Description
The biologically active form of TGF-β1 (transforming growth factor-β1 human) exists as a disulphide-linked homodimer. In mammals, three isoforms of TGF-β has been identified : TGF-β1, TGF-β2 and TGF-β3. TGF-β1 encodes a 25 kDa peptide. TGF-β1 precursor polypeptide is characterized with hydrophobic signal sequence, pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The TGF-β1 gene is mapped to human chromosome 19q13.2.
Biochem/physiol Actions
TGF-β1 is produced by many cell types, but is reported to be most concentrated in mammalian platelets, where it is present at approximately four times the level of TGF-β2.
AMINOPEPTIDASE M Preparation Products And Raw materials
Raw materials
Preparation Products
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