ChemicalBook > CAS DataBase List > AMINOPEPTIDASE M

AMINOPEPTIDASE M

Product Name
AMINOPEPTIDASE M
CAS No.
9054-63-1
Chemical Name
AMINOPEPTIDASE M
Synonyms
LAP;CRP2;TCF5;AP-M;IL6DBP;TGF-β1;hTGF-β1;anjitaimei;M/AP-M/LAP;EC 3.4.11.1
CBNumber
CB4166931
Molecular Formula
C12H24O2
Formula Weight
0
MOL File
Mol file
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AMINOPEPTIDASE M Property

storage temp. 
2-8°C
form 
powder
color 
white
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-21
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T7039
Product name
Transforming Growth Factor-β1 human
Purity
TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture
Packaging
2μg
Price
$373
Updated
2024/03/01
Sigma-Aldrich
Product number
T7039
Product name
Transforming Growth Factor-β1 human
Purity
TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture
Packaging
50μg
Price
$1030
Updated
2024/03/01
Sigma-Aldrich
Product number
L6007
Product name
Leucine Aminopeptidase, microsomal from porcine kidney
Purity
Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
Packaging
25units
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
L6007
Product name
Leucine Aminopeptidase, microsomal from porcine kidney
Purity
Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
Packaging
50units
Price
$860
Updated
2024/03/01
Sigma-Aldrich
Product number
L6007
Product name
Leucine Aminopeptidase, microsomal from porcine kidney
Purity
Type VI-S, lyophilized powder, ≥12?units/mg protein (biuret)
Packaging
100units
Price
$1570
Updated
2024/03/01
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AMINOPEPTIDASE M Chemical Properties,Usage,Production

Uses

Transforming Growth Factor-β1 (TGF-β) human has been used :

  • to study the expression of PDGFRB (Platelet derived growth factor receptor β) in association with transforming growth factor-β signaling.
  • to stimulate lung fibrosis in human fetal lung fibroblast cell line in order to further measure the in-plane elasticity of live cell layers using a pressure sensor embedded microfluidic device.
  • to study the effect of TGF-β on HTRA1 (high-temperature requirement A1)-affected Wnt target genes.

Uses

Leucine Aminopeptidase, microsomal from porcine kidney has been used in aminopeptidase N (APN) inhibitor screening assay in adenocarcinoma cell line ES-2 and in the inhibition kinetic studies with APN inhibitor.

General Description

The biologically active form of TGF-β1 (transforming growth factor-β1 human) exists as a disulphide-linked homodimer. In mammals, three isoforms of TGF-β has been identified : TGF-β1, TGF-β2 and TGF-β3. TGF-β1 encodes a 25 kDa peptide. TGF-β1 precursor polypeptide is characterized with hydrophobic signal sequence, pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The TGF-β1 gene is mapped to human chromosome 19q13.2.

Biochem/physiol Actions

TGF-β1 is produced by many cell types, but is reported to be most concentrated in mammalian platelets, where it is present at approximately four times the level of TGF-β2.

AMINOPEPTIDASE M Preparation Products And Raw materials

Raw materials

Hexadecyl trimethyl ammonium bromide

Preparation Products

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9054-63-1, AMINOPEPTIDASE MRelated Search:

1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Aluminum acetylacetonate PHENYLSELENOL COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) SALCOMINE Ferric acetylacetonate TERT-BUTYL ISOCYANIDE Benzyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tosylmethyl isocyanide Cupric acetylacetonate N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) METHYL ISOCYANOACETATE DIPEPTIDYL AMINOPEPTIDASE IV

  • AMINO ACID ARYLAMIDASE
  • AMINOPEPTIDASE M
  • AMINOPEPTIDASE M, 20 UNITS
  • AMINOPEPTIDASE (MICROSOMAL)
  • AMINOPEPTIDASE M, PORCINE KIDNEY
  • AMINOPEPTIDASE M TYPE IV-S
  • AMINOPEPTIDASE M TYPE VI
  • AMINOPEPTIDASE M TYPE VI-S
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE (CYTOSOL)
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE (MICROSOMAL)
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE IV-S
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE VI
  • Alanine aminopeptidase, microsomal
  • Arylamidase from Human placenta
  • hTGF-β1
  • CRP2
  • IL6DBP
  • Monoclonal Anti-CEBPB antibody produced in mouse
  • TCF5
  • latency-associated peptide
  • TGF-β1 Latent human
  • Transforming Growth Factor-β1 from porcine platelets
  • Leucinaminopeptidase
  • Transforming Growth Factor-β1 from human platelets
  • Transforming Growth Factor-β1 human
  • Microsomal aminopeptidase
  • Aminopeptidase PepN
  • Aminopeptidase N/CD13
  • Aminopeptidase M II
  • Alanyl aminopeptidase
  • Alanine-specific aminopeptidase
  • Alanine aminopeptidase
  • anjitaimei
  • TGF-β1
  • Transforming Growth Factor-β1 Latency Associated Peptide human
  • ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE VI-S
  • LEUCINE AMINOPEPTIDASE
  • LEUCINE AMINOPEPTIDASE, MICROSOMAL
  • LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE IV-S
  • LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE VI
  • LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE VI-S
  • EC 3.4.11.1
  • EC 3.4.11.2
  • EC 3.4.11.2 TYPE IV-S
  • EC 3.4.11.2 TYPE VI
  • EC 3.4.11.2 TYPE VI-S
  • AP-M
  • PARTICLE-BOUND AMINOPEPTIDASE TYPE IV-S
  • PARTICLE-BOUND AMINOPEPTIDASE TYPE VI
  • PARTICLE-BOUND AMINOPEPTIDASE TYPE VI-S
  • ALANINE AMINOPEPTIDASE FROM BOVINEINTEST INAL MUCOS
  • LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE IV-S FROM P
  • LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~5 U/MG*
  • LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~18 U/MG*
  • LEUCINE AMINOPEPTIDASE MICROSOMAL*SEQUEN CING GRADE
  • LEUCINE AMINOPEPTIDASE MICROSOMAL*TYPE V I FROM PORC
  • LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~10 U/MG*