4-Hydroxyisophthalic acid

Product Name: 4-Hydroxyisophthalic acid
CAS No.: 636-46-4
Chemical Name: 4-Hydroxyisophthalic acid
Synonyms: 4-hipa;NSC 2445;Eupirina;Aspirin IMpurity B;Aspirin Impurity 2;RARECHEM AL BE 0104;4-Hydroxyisophthalic;Aspirin EP IMpurity B;4-hydroxy-isophthalicaci;4-HYDROXYISOPHTHALIC ACID
CBNumber: CB4234715
Molecular Formula: C8H6O5
Formula Weight: 182.13
MOL File: 636-46-4.mol

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4-Hydroxyisophthalic acid Property

Melting point:: >300°C
Boiling point:: 310 C
Density: 1.4411 (rough estimate)
refractive index: 1.5690 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: solid
pka: 2?+-.0.10(Predicted)
color: White to Pale Purple
Water Solubility: 0.3g/L(24 ºC)
Merck: 14,4827
Stability:: Hygroscopic
InChI: 1S/C8H6O5/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3,9H,(H,10,11)(H,12,13)
InChIKey: BCEQKAQCUWUNML-UHFFFAOYSA-N
SMILES: OC(C1=CC(C(O)=O)=C(O)C=C1)=O
CAS DataBase Reference: 636-46-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-41-22-36/38
Safety Statements: 26-36/37/39-36-39-6
WGK Germany: 3
RTECS: NT2544000
HS Code: 29182900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000405
Product name: Salicylic acid impurity B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 15 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: 797057
Product name: 4-Hydroxyisophthalic acid
Purity: 95%
Packaging: 250mg
Price: $139
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1609024
Product name: Salicylic acid Related Compound B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 100mg
Price: $1360
Updated: 2025/07/31

TCI Chemical

Product number: H0257
Product name: 4-Hydroxyisophthalic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $91
Updated: 2025/07/31

TCI Chemical

Product number: H0257
Product name: 4-Hydroxyisophthalic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $273
Updated: 2025/07/31

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4-Hydroxyisophthalic acid Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

4-Hydroxyisophthalic acid has been proposed as an improvement over aspirin. An impurity of Acetylsalicylic acid (A187780). Acetylsalicylic Acid Impurity B; Aspirin Impurity B

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Hydroxyisophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxyisophthalic acid Suppliers

Americas 1 Belgium 1 Canada 2 China 170 Europe 1 Germany 4 India 32 Japan 3 Mexico 1 Norway 1 Switzerland 1 Ukraine 1 United Kingdom 19 United States 47 Global 284

J & K SCIENTIFIC LTD.

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Nanjing Chemlin Chemical Co., Ltd

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View Lastest Price from 4-Hydroxyisophthalic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Hydroxyisophthalic acid 636-46-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-12

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 4-Hydroxyisophthalic acid 636-46-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-11

Henan Fengda Chemical Co., Ltd

Product: 4-Hydroxyisophthalic acid 636-46-4
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-16

636-46-4, 4-Hydroxyisophthalic acidRelated Search:

SALICYLIC ACID, IMP. B (EP): 4-HYDROXYISOPHTHALIC ACID MM(CRM STANDARD) 2'-Hydroxy-3-phenylpropiophenone Isophthalic acid 5-Aminoisophthalic acid Methylparaben Isopropylparaben Butylparaben 3-Hydroxybenzoic acid CHLOROPHOSPHONAZO III Terephthalic acid 4-Hydroxyphthalic acid 4-Hydroxybenzoic acid DIMETHYL 4-HYDROXYISOPHTHALATE HYDROXYISOPHTHALIC ACID, 5-,5-HYDROXYISOPHTHALIC ACID 4-Methoxyisophthalic acid 5-HYDROXYBENZENE-1,2,4-TRICARBOXYLIC ACID 2-Hydroxy-m-phthalic acid 5-HYDROXYISOPHTHALIC ACID DIMETHYL,Dimethyl 5-hydroxybenzene-1,3-dicarboxylate~5-Hydroxyisophthalic acid dimethyl ester,5-HYDROXYISOPHTHALIC ACID DIMETHYL ESTER

HYDROXYISOPHTHALIC ACID, 4-

4-HYDROXYISOPHTHALIC ACID

4-HYDROXYBENZENE-1,3-DICARBOXYLIC ACID

4-HYDROXY-1,3-BENZENEDECARBOXYLIC ACID

4-HYDROXY-1,3-BENZENEDICARBOXYLIC ACID

ACETYLSALISYLIC ACID IMP B

NSC 2445

Aspirin EP IMpurity B

Aspirin IMpurity B

Acetylsalicylic Acid IMpurity B (Aspirin IMpurity B)

1,3-Benzenedicarboxylicacid, 4-hydroxy-

Aspirin Impurity 2

4-Hydroxyisophthalic Acid(Salicylic Acid RCB)

Acetylsalicylic Acid EP Impurity B

Acetylsalicylic Acid Impurity 2（Acetylsalicylic Acid EP Impurity B）

4-hipa

4-hydroxy-3-benzenedicarboxylicacid

4-hydroxy-isophthalicaci

RARECHEM AL BE 0104

4-HYDROYLISOPHTHALIC ACID

4-Hydroxyisophthalic

4-Hydroxy Isophthallic Acid

4-Hydroxy-m-phthalic acid

Eupirina

4-Hydroxyisophthalic acid,98%

Salicylic Acid Related Compound B (100 mg) (4-hydroxyisophthalic acid)

4-Hydroxyisophthalic acid (4-Hydroxybenzene-1,3-dicarboxylic acid)

Salicylic Acid EP Impurityuriy B

4-Hydroxyisophthalic acid(4-HIPA)

Acetylsalicylic Acid EP Impurity B (Aspirin Impurity B)

4-HydroxyisophthalicAcid&gt

Salicylic acid impurity B CRS

Acetylsalicylic Acid Impurity B

4-Hydroxy Isopthalic acid

Mesalazine Impurity(4-hydroxylphthallic acid)

Acetylsalicylic Acid EP Impurity B (4-Hydroxyisophthalic Acid)

Aspirin Impurity BQ: What is Aspirin Impurity B Q: What is the CAS Number of Aspirin Impurity B Q: What is the storage condition of Aspirin Impurity B Q: What are the applications of Aspirin Impurity B

Salicylic Acid Related Compound B (4-hydroxyisophthalic acid) (1609024)

Salicylic Acid USP Related Compound B

Aspirin (Acetylsalicylic Acid) EP Impurity B

Salicylic Acid EP Impurity B

Acetylsalicylic Acid EP Impurity B (Salicylic Acid USP Related Compound B)

4-Hydroxyisophthalic acid-RM

HYDROXYISOPHTHALIC ACID 4-(RG) 1g

4-Hydroxyisophthalicacid(AspirinImpurity)

636-46-4

610-35-6

Aromatics, Impurities

API intermediates

Phthalic Acids, Esters and Derivatives

Aromatics

Impurities