3ALPHA-HYDROXYSTEROID DEHYDROGENASE

Product Name: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE
CAS No.: 9028-56-2
Chemical Name: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE
Synonyms: HSD;3αHSD;3α-HSD;EC 1.1.1.50;EC: 1.1.1.50;3α-Hydroxysteroid;3 α - Steroid Dehydrogenase;HYDROXYSTEROID OXIDOREDUCTASE;3α-Hydroxysteroid Dehydrogenase;3-a-Hydroxysteroid dehydrogenase
CBNumber: CB4236380
Formula Weight: 0
MOL File: Mol file

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3ALPHA-HYDROXYSTEROID DEHYDROGENASE Property

storage temp.: -20°C
form: ammonium sulfate suspension
color: White to off-white
biological source: bacterial (Pseudomonas testosteroni)
Specific Activity: ≥15units/mg protein
Cosmetics Ingredients Functions: SKIN CONDITIONING

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 35079090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H1506
Product name: 3α-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni
Purity: ≥15?units/mg protein
Packaging: 50units
Price: $635.55
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: ENZ0000056
Product name: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE
Purity: 95.00%
Packaging: 5MG
Price: $499.71
Updated: 2021/12/16

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3ALPHA-HYDROXYSTEROID DEHYDROGENASE Chemical Properties,Usage,Production

Description

3α-Hydroxysteroid dehydrogenase is a key enzyme catalyzing steroid metabolism. Its core function is to reversibly catalyze the oxidation of 3α-hydroxysteroids to 3-oxosteroids, using NAD+ or NADP+ as cofactors. As a protein, its molecular weight and optimal reaction conditions vary depending on the source (e.g., human, rat, or bacterial) and subtype. For example, some human subtypes prefer to use NADPH as a cofactor and exhibit optimal activity in a near-neutral environment with a pH of 6.8–7.4. The purified product is typically a white powder.

Chemical Properties

Powder

Uses

3α-Hydroxysteroid Dehydrogenase from Pseudomonas testosterone has been used:

in the preparation of composite electrode platform to for the determination of androsterone
in potassium phosphate buffer for the bioluminescent assay of bile acids in serum
for total bile salts assay using an enzymatic method

Application

3α-Hydroxysteroid dehydrogenase (3α-HSD) plays a crucial physiological role in vivo, responsible for inactivating circulating steroid hormones and regulating their activity in target tissues (especially the liver), thus participating in steroid hormone clearance. In vitro, purified 3α-HSD is widely used as a biochemical reagent, primarily for clinical diagnosis and research. For example, it can be used to determine enzyme activity levels for quantitative analysis of bile acid or certain steroid hormone levels. Furthermore, it is an important tool for studying the mechanisms of action of nonsteroidal anti-inflammatory drugs (NSAIDs) and progestins, as these drugs are often found to be inhibitors of this enzyme.

Biochem/physiol Actions

3α-hydroxysteroid dehydrogenase (3α-HSD) may help to modulate the occupancy of the androgen receptor (AR) in androgen target tissues. It may also act in hindering androgen action.

3ALPHA-HYDROXYSTEROID DEHYDROGENASE Preparation Products And Raw materials

Raw materials

Preparation Products

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3ALPHA-HYDROXYSTEROID DEHYDROGENASE Suppliers

CHINA 121 Germany 1 Japan 1 Switzerland 1 United States 7 Global 131

Shanghai Baoman Biotechnology Co., Ltd.

Tel: 021-62130998
Fax: 021-54438215
Email: baomanbio@163.com
Country: China
ProdList: 126
Advantage: 55

J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
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Tel: 0731-85526065 13308475853
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Sigma-Aldrich

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Watson Biotechnology Co.,Ltd

Tel: 027-59207879 1972026995 18140587686
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Alfa Chemistry

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View Lastest Price from 3ALPHA-HYDROXYSTEROID DEHYDROGENASE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 3α-Hydroxysteroid Dehydrogenase 9028-56-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98.0%
Supply Ability: 1kg/month
Release date: 2021-08-25

Anhui Ruihan Technology Co., Ltd

Product: 3alpha-hydroxysteroid dehydrogenase 9028-56-2
Price: US $50.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 TONS
Release date: 2023-08-30

Hubei Xindesheng Material Technology Co., Ltd.

Product: hydroxysteroid dehydrogenase 9028-56-2
Price: US $13.50-8.20/KU
Min. Order: 10KU
Purity: ≥20U/mg
Supply Ability: 10000ku
Release date: 2020-11-04

9028-56-2, 3ALPHA-HYDROXYSTEROID DEHYDROGENASERelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 2,4-PENTANEDIONE, SILVER DERIVATIVE Tosylmethyl isocyanide Ferric acetylacetonate N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) PHENYLSELENOL COBALT(II) ACETYLACETONATE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Aluminum acetylacetonate Benzyl isocyanide TERT-BUTYL ISOCYANIDE Ethyl isocyanoacetate Tris(2,4-pentanedionato)chroMiuM(III) METHYL ISOCYANOACETATE Cupric acetylacetonate 12-ALPHA-HYDROXYSTEROID DEHYDROGENASE

3ALPHA-HYDROXYSTEROID DEHYDROGENASE

3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE

3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg

3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni

Dehydrogenase, 3alpha-hydroxy steroid

HYDROXYSTEROID OXIDOREDUCTASE

3ALPHA-HYDROXYSTEROID DEHYDROGENASE F. &

3A-HYDROXYSTEROID DEHYDROGENASE FROM*PSE UDOMONAS TE

3-alpha-Hydroxysteroidedehydrogenase

3α-hydroxysteroid dehydrogenase from pseudomonas testosteroni

3α-hydroxysteroid:nad(p)+ oxidoreductase

EC 1.1.1.50

EC: 1.1.1.50

3α-Hydroxysteroid Dehydrogenase [>=50 units/mg]

3alpha-Hydroxysteroid oxidoreductase

3α-Hydroxysteroid

HSD

3α-Hydroxysteroid Dehydrogenase, 90 units/Mg

3α-Hydroxysteroid Dehydrogenase, >=90 units/mg protein

3α-Hydroxysteroid Dehydrogenase froM MicroorganisM

Dehydrogenase, 3a-hydroxy steroid

3α-Hydroxysteroid Dehydrogenase, 28 kDa (SDS-PAGE)

3α-Hydroxysteroid Dehydrogenase, Recombinant

3α-hydroxysteroid 3-dehydrogenase (Re-specific)

3α-hydroxysteroid 3-dehydrogenase (Si-specific)

3α-Hydroxysteroid Dehydrogenase from B. choshinensis, Recombinant

Native Pseudomonas testosteroni 3α-Hydroxysteroid Dehydrogenase

3αHSD

3α-Hydroxysteroid Dehydrogenase

3ALPHA-HYDROXYSTEROID DEHYDROGENASE USP/EP/BP

three α Hydroxysteroid dehydrogenase

3-a-Hydroxysteroid dehydrogenase

3α-HSD

3α-Hydroxysteroid dehydrogenase（HSD）

3α-Hydroxysteroid Dehydrogenase from <i>Pseudomonas testosteroni</i>

3-alpha Hydroxysteroid Dehydrogenase Activity Microplate Assay Kit

3ALPHA-HYDROXYSTEROID DEHYDROGESE

3α-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni

3 α - Steroid Dehydrogenase

9028-56-2

Diagnostic and Analytical Enzymes

BioChemical

Application Index

Biochemicals and Reagents

Enzymes, Inhibitors, and Substrates

Oxidoreductases

Specialty Enzymes