ChemicalBook > CAS DataBase List > D-(-)-3-Acetylthio-2-methylpropionic acid

D-(-)-3-Acetylthio-2-methylpropionic acid

Product Name
D-(-)-3-Acetylthio-2-methylpropionic acid
CAS No.
76497-39-7
Chemical Name
D-(-)-3-Acetylthio-2-methylpropionic acid
Synonyms
Captopril Impurity K;Captopril Impurity V;Captopril Impurity 7;Captopril EP Impurity G (S-Isomer);(2S)-3-(Acetylthio)-2-methylpropano;(S)-β-(Acetylmercapto)isobutyric acid;(S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID;(S)-β-(Acetylmercapto)isobutyric acid;D-(-)-3-Acetylthio-2-Methylpropionic A;Captopril Impurity G as (S)-enantiomer
CBNumber
CB4240644
Molecular Formula
C6H10O3S
Formula Weight
162.21
MOL File
76497-39-7.mol
More
Less

D-(-)-3-Acetylthio-2-methylpropionic acid Property

Melting point:
5 °C
Boiling point:
120-132 °C (1 mmHg)
alpha 
-46 º (c=1, 96% EtOH)
Density 
1.178 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.490
Flash point:
>230 °F
storage temp. 
Store at 0-5°C
solubility 
Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form 
liquid
pka
4.22±0.10(Predicted)
Water Solubility 
INSOLUBLE
CAS DataBase Reference
76497-39-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C,T
Risk Statements 
34-36-24/25
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
HS Code 
29309070
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A1334
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity
>98.0%(T)
Packaging
5mL
Price
$74
Updated
2021/12/16
TCI Chemical
Product number
A1334
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity
>98.0%(T)
Packaging
25mL
Price
$220
Updated
2021/12/16
TRC
Product number
A188770
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
A188770
Product name
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging
500mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0001116
Product name
(S)-(-)-3-ACETYLTHIO-2-METHYLPROPIONIC ACID
Purity
95.00%
Packaging
1G
Price
$120.75
Updated
2021/12/16
More
Less

D-(-)-3-Acetylthio-2-methylpropionic acid Chemical Properties,Usage,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

ACE-inhibitors.

Uses

S-Acetylthio-2-methylpropionic acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.

D-(-)-3-Acetylthio-2-methylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

D-(-)-3-Acetylthio-2-methylpropionic acid Suppliers

Jiangsu Greature Bio-Medicine Co., Ltd.
Tel
0512-85557988 18662338937
Fax
0512-85557182
Email
frank.wang@greature.com.cn
Country
China
ProdList
97
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19173
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
More
Less

View Lastest Price from D-(-)-3-Acetylthio-2-methylpropionic acid manufacturers

Career Henan Chemical Co
Product
D-(-)-3-Acetylthio-2-methylpropionic acid 76497-39-7
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-15

76497-39-7, D-(-)-3-Acetylthio-2-methylpropionic acidRelated Search:


  • D(-)S-ACETYL-BETA-MERCAPTO ISOBUTYRIC ACID
  • D-(S)-3-ACETYL-3-MERCAPTO-2-METHYL PROPANOIC ACID
  • D-(-)-3-ACETYLSULFANYL-2-METHYLPROPIONIC ACID
  • d-(-)-3-acetylthio-2-methylpropionic acid
  • (S)-β-(Acetylmercapto)isobutyric acid
  • D-3-(Acetylthio)-2-methylpropanoic acid
  • D-(S)-3-Acetylthio-2-methylpropionic acid
  • (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONI&
  • (-)-3-(Acetylthio)-2-methylpropanoic acid (Captopril Intermediate)
  • (S)-BETA-(ACETYLMERCAPTO)ISOBUTYRIC ACID
  • (S)-(-)-BETA-ACETYLTHIO-2-METHYLPROPIONIC ACID
  • (S)-(-)-3-(ACETYLMERCAPTO)ISOBUTYRIC ACID
  • (S)-(-)-3-ACETYLTHIO-2-METHYLPROPANOIC ACID
  • (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID
  • (S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID
  • (S)-ACETYL-3-MERCAPTO-2-METHYLPROPANOIC ACID
  • (S)-(-)-ACETYLTHIO 2-METHYLPROPIONIC ACID
  • (S)-β-(Acetylmercapto)isobutyric acid, D-(-)-S-Acetyl-β-mercaptoisobutyric acid
  • Propanoic acid, 3-(acetylthio)-2-methyl-, (2S)-
  • (2S)-3-Acetylsulfanyl-2-methylpropanoate
  • (2S)-2-Methyl-3-(acetylthio)propionic acid
  • (S)-2-Methyl-3-(acetylthio)propionic acid
  • D(-)-S-Acetyl-beta-mercaptoisobutyric acid,99%
  • (S)-3-Acetylsulfanyl-2-Methylpropionic Acid
  • D-(-)-3-Acetylthio-2-Methylpropionic A
  • (2S)-3-(Acetylsulphanyl)-2-methylpropanoic acid, (2S)-3-(Acetylthio)-2-methylpropionic acid
  • Captopril Impurity K
  • Captopril EP Impurity G (S-Isomer)
  • (2S)-3-acetylthio-2-methylpropionic acid, D-(-)-S-3-acetylthio-2-methylpropanoic acid, (2S)-3-Acetylthio-2-methylpropanoic acid, (S)-3-(acetylthio)isobutyric acid, (S)-(-)-acetyl-β-mercaptoisobutyric acid, D-(-)-S-acetyl-β-mercaptoisobutyric acid, (S)-3-acetylsulfanyl-2-methyl-propionic acid
  • (S)-(-)-3-(Acetylthio)-2-methylpropionic acid≥ 99% ee (GC)
  • Captopril Impurity V
  • (2S)-3-acetylthio-2-methylpropionic acid
  • (2S)-3-(Acetylthio)-2-methylpropano
  • Captopril Impurity 7
  • (S)-β-(Acetylmercapto)isobutyric acid
  • Captopril Impurity G as (S)-enantiomer
  • Captopril EP Impurity G as (S)-enantiomer
  • 76497-39-7
  • 79497-39-7
  • C6H10O3S
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Thiocarbonyl Compounds
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry