D-(-)-3-Acetylthio-2-methylpropionic acid

Product Name: D-(-)-3-Acetylthio-2-methylpropionic acid
CAS No.: 76497-39-7
Chemical Name: D-(-)-3-Acetylthio-2-methylpropionic acid
Synonyms: Captopril Impurity K;Captopril Impurity V;Captopril Impurity 7;Captopril EP Impurity G (S-Isomer);(2S)-3-(Acetylthio)-2-methylpropano;(S)-β-(Acetylmercapto)isobutyric acid;(S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID;(S)-β-(Acetylmercapto)isobutyric acid;D-(-)-3-Acetylthio-2-Methylpropionic A;Captopril Impurity G as (S)-enantiomer
CBNumber: CB4240644
Molecular Formula: C6H10O3S
Formula Weight: 162.21
MOL File: 76497-39-7.mol

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D-(-)-3-Acetylthio-2-methylpropionic acid Property

Melting point:: 5 °C
Boiling point:: 120-132 °C (1 mmHg)
alpha: -46 º (c=1, 96% EtOH)
Density: 1.178 g/mL at 20 °C(lit.)
refractive index: n20/D 1.490
Flash point:: >230 °F
storage temp.: Store at 0-5°C
solubility: Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form: liquid
pka: 4.22±0.10(Predicted)
Water Solubility: INSOLUBLE
CAS DataBase Reference: 76497-39-7(CAS DataBase Reference)

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Safety

Hazard Codes: C,T
Risk Statements: 34-36-24/25
Safety Statements: 26-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
HS Code: 29309070

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A1334
Product name: (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity: >98.0%(T)
Packaging: 5mL
Price: $74
Updated: 2021/12/16

TCI Chemical

Product number: A1334
Product name: (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Purity: >98.0%(T)
Packaging: 25mL
Price: $220
Updated: 2021/12/16

TRC

Product number: A188770
Product name: (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A188770
Product name: (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid
Packaging: 500mg
Price: $110
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6166-1-S1
Product name: (2S)-3-(Acetylthio)-2-methylpropanoic acid
Packaging: 1g
Price: $26
Updated: 2021/12/16

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D-(-)-3-Acetylthio-2-methylpropionic acid Chemical Properties,Usage,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

ACE-inhibitors.

Uses

S-Acetylthio-2-methylpropionic acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.

D-(-)-3-Acetylthio-2-methylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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D-(-)-3-Acetylthio-2-methylpropionic acid Suppliers

Canada 1 China 96 Europe 1 France 1 Germany 3 India 5 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 10 United States 19 Global 140

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View Lastest Price from D-(-)-3-Acetylthio-2-methylpropionic acid manufacturers

Career Henan Chemical Co

Product: D-(-)-3-Acetylthio-2-methylpropionic acid 76497-39-7
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

76497-39-7, D-(-)-3-Acetylthio-2-methylpropionic acidRelated Search:

Butyl levulinate 3-Mercaptopropionic acid Citric acid Levulinic acid Folic acid Isobutyric acid 2,2-Bis(hydroxymethyl)propionic acid Acetyl chloride Glycine Methyl levulinate Ethyl 2-(Chlorosulfonyl)acetate Acetylacetone Ascoric Acid 2-Mercaptoethanol (R)-(+)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID METHYL ESTER 3-ACETYLTHIO-2-METHYLPROPIONIC ACID,DL-BETA-ACETYLTHIO-ALPHA-METHYLPROPIONIC ACID,3-ACETYLTHIO-2-METHYLPROPANOIC ACID Propionic acid Captopril

D(-)S-ACETYL-BETA-MERCAPTO ISOBUTYRIC ACID

D-(S)-3-ACETYL-3-MERCAPTO-2-METHYL PROPANOIC ACID

D-(-)-3-ACETYLSULFANYL-2-METHYLPROPIONIC ACID

d-(-)-3-acetylthio-2-methylpropionic acid

(S)-β-(Acetylmercapto)isobutyric acid

D-3-(Acetylthio)-2-methylpropanoic acid

D-(S)-3-Acetylthio-2-methylpropionic acid

(S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONI&

(-)-3-(Acetylthio)-2-methylpropanoic acid (Captopril Intermediate)

(S)-BETA-(ACETYLMERCAPTO)ISOBUTYRIC ACID

(S)-(-)-BETA-ACETYLTHIO-2-METHYLPROPIONIC ACID

(S)-(-)-3-(ACETYLMERCAPTO)ISOBUTYRIC ACID

(S)-(-)-3-ACETYLTHIO-2-METHYLPROPANOIC ACID

(S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID

(S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID

(S)-ACETYL-3-MERCAPTO-2-METHYLPROPANOIC ACID

(S)-(-)-ACETYLTHIO 2-METHYLPROPIONIC ACID

(S)-β-(Acetylmercapto)isobutyric acid, D-(-)-S-Acetyl-β-mercaptoisobutyric acid

Propanoic acid, 3-(acetylthio)-2-methyl-, (2S)-

(2S)-3-Acetylsulfanyl-2-methylpropanoate

(2S)-2-Methyl-3-(acetylthio)propionic acid

(S)-2-Methyl-3-(acetylthio)propionic acid

D(-)-S-Acetyl-beta-mercaptoisobutyric acid,99%

(S)-3-Acetylsulfanyl-2-Methylpropionic Acid

D-(-)-3-Acetylthio-2-Methylpropionic A

(2S)-3-(Acetylsulphanyl)-2-methylpropanoic acid, (2S)-3-(Acetylthio)-2-methylpropionic acid

Captopril Impurity K

Captopril EP Impurity G (S-Isomer)

(2S)-3-acetylthio-2-methylpropionic acid, D-(-)-S-3-acetylthio-2-methylpropanoic acid, (2S)-3-Acetylthio-2-methylpropanoic acid, (S)-3-(acetylthio)isobutyric acid, (S)-(-)-acetyl-β-mercaptoisobutyric acid, D-(-)-S-acetyl-β-mercaptoisobutyric acid, (S)-3-acetylsulfanyl-2-methyl-propionic acid

(S)-(-)-3-(Acetylthio)-2-methylpropionic acid≥ 99% ee (GC)

Captopril Impurity V

(2S)-3-acetylthio-2-methylpropionic acid

(2S)-3-(Acetylthio)-2-methylpropano

Captopril Impurity 7

(S)-β-(Acetylmercapto)isobutyric acid

Captopril Impurity G as (S)-enantiomer

Captopril EP Impurity G as (S)-enantiomer

76497-39-7

79497-39-7

C6H10O3S

Carboxylic Acids (Chiral)

Chiral Building Blocks

Asymmetric Synthesis

Organic Building Blocks

Thiocarbonyl Compounds

Carboxylic Acids (Chiral)

Chiral Building Blocks

Synthetic Organic Chemistry