Acetyl-CoA synthetase

Product Name
Acetyl-CoA synthetase
CAS No.
9012-31-1
Chemical Name
Acetyl-CoA synthetase
Synonyms
EC 6.2.1.1;ACETATE THIOKINASE;ACETATE: COA LIGASE;ACETYL-COA SYNTHETASE;Synthetase, acetyl coenzyme A;S-ACETYL COENZYME A SYNTHETASE;acetate coa ligase (amp forming);S-acetyl coenzyme A synthetase*from bakers yeast;ACETATE THIOKINASE: ACETATE: COA LIGASE [AMP FORMING];Acetate CoA ligase (AMP forming), Acetate thiokinase
CBNumber
CB4254049
Formula Weight
0
MOL File
Mol file
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Acetyl-CoA synthetase Property

storage temp. 
-20°C
form 
lyophilized powder
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1765
Product name
S-Acetyl-coenzyme A synthetase from baker's yeast (S. cerevisiae)
Purity
lyophilized powder, ≥3 units/mg protein
Packaging
5mg
Price
$289
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
ENZ0008449
Product name
ACETYL-COA SYNTHETASE
Purity
95.00%
Packaging
5MG
Price
$450.92
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ENZ0000751
Product name
ACETATE COA LIGASE(AMP FORMING)
Purity
95.00%
Packaging
5MG
Price
$505.03
Updated
2021/12/16
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Acetyl-CoA synthetase Chemical Properties,Usage,Production

Uses

S-Acetyl-coenzyme A synthetase may be used to study various metabolic pathways, such as glycolysis, gluconeogenesis, pyruvate metabolism and CO2 fixation. It may also be used in gene expression studies.

Biochem/physiol Actions

Acetyl-coenzyme A synthetase catalyzes the production of acetyl-CoA. It is involved in histone acetylation in the nucleus. It may be involved in the growth of nonfermentable carbon sources such as glycerol. Acetyl-coenzyme A synthetase is induced by acetate, acetaldehyde and ethanol .

Purification Methods

This enzyme has been purified by extraction into phosphate buffer pH 6.8-7.0 containing 2-mercaptoethanol and EDTA, protamine sulfate precipitation, polyethylene glycol fractionation, Alumina  gel filtration, concentration by (NH4)2SO4 precipitation, Bio-Gel A-0.5m chromatography and DEAE-cellulose gradient chromatography. It has Km (apparent) 0.24mM (for acetate) and 0.035mM (for CoA); 1.2 mM for ATP and Mg2+ 4.0mM. [Frenkel & Kitchens Methods Enzymol 71 317 1981.]

Acetyl-CoA synthetase Preparation Products And Raw materials

Raw materials

Preparation Products

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Acetyl-CoA synthetase Suppliers

China 9 France 1 India 1 Japan 1 Switzerland 1 United States 4 Global 17
SIGMA-RBI
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Country
Switzerland
ProdList
6896
Advantage
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9012-31-1, Acetyl-CoA synthetaseRelated Search:

Cupric acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE PHENYLSELENOL Ethyl isocyanoacetate Benzyl isocyanide Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE Aluminum acetylacetonate METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE SALCOMINE Tosylmethyl isocyanide BAKERS YEAST

  • S-acetyl coenzyme A synthetase*from bakers yeast
  • Synthetase, acetyl coenzyme A
  • acetate coa ligase (amp forming)
  • s-acetyl-coenzyme a synthetase from baker's yeast (s. cerevisiae)
  • Acetate CoA ligase (AMP forming), Acetate thiokinase
  • ACETYL-COA SYNTHETASE
  • ACETATE: COA LIGASE
  • ACETATE THIOKINASE
  • ACETATE THIOKINASE: ACETATE: COA LIGASE [AMP FORMING]
  • EC 6.2.1.1
  • S-ACETYL COENZYME A SYNTHETASE
  • Native Bakers yeast (S. cerevisiae) S-Acetyl-coenzyme A synthetase
  • Acetyl-coenzyme A synthetase from Bacillus subtilis, Recombinant
  • S-Acetyl-coenzyme A, synthetase from baker's yeast (S. cerevisiae) lyophilized powder, ≥3 units/mg protein
  • 9012-31-1
  • Metabolomics
  • General Metabolic Enzymes A-H
  • General Metabolic Enzymes
  • BioChemical