5-Chlorothiophene-2-sulfonyl chloride

Product Name: 5-Chlorothiophene-2-sulfonyl chloride
CAS No.: 2766-74-7
Chemical Name: 5-Chlorothiophene-2-sulfonyl chloride
Synonyms: AKOS B019398;BUTTPARK 27\04-09;TIMTEC-BB SBB003378;ART-CHEM-BB B019398;5-chlorothiophene-2-sulfonyl;5-CHLOROTHIOPHENESULPHONYL CHLORIDE;5-CHLORO-2-THIENYLSULFONYL CHLORIDE;5-Chlorothiophen-2-sulfonyl chloride;5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE;5-CHLORO-2-THIOPHENESULFONYL CHLORIDE
CBNumber: CB4283960
Molecular Formula: C4H2Cl2O2S2
Formula Weight: 217.09
MOL File: 2766-74-7.mol

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5-Chlorothiophene-2-sulfonyl chloride Property

Melting point:: 25-28°C
Boiling point:: 112-117 °C (lit.)
Density: 1.623 g/mL at 25 °C (lit.)
refractive index: n20/D 1.586(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
form: solid
Specific Gravity: 1.623
color: Colorless to Yellow to Orange
Water Solubility: Not miscible in water.
Sensitive: Moisture Sensitive
BRN: 130710
InChIKey: SORSTNOXGOXWAO-UHFFFAOYSA-N
CAS DataBase Reference: 2766-74-7(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34-29-14
Safety Statements: 26-27-36/37/39-45-28A-25
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: II
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 544272
Product name: 5-Chlorothiophene-2-sulfonyl chloride
Purity: 96%
Packaging: 5g
Price: $17.16
Updated: 2024/03/01

Sigma-Aldrich

Product number: 544272
Product name: 5-Chlorothiophene-2-sulfonyl chloride
Purity: 96%
Packaging: 1g
Price: $25
Updated: 2023/06/20

TCI Chemical

Product number: C2343
Product name: 5-Chloro-2-thiophenesulfonyl Chloride
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $59
Updated: 2024/03/01

TCI Chemical

Product number: C2343
Product name: 5-Chloro-2-thiophenesulfonyl Chloride
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $236
Updated: 2024/03/01

Alfa Aesar

Product number: A11348
Product name: 5-Chlorothiophene-2-sulfonyl chloride, 97%
Packaging: 1g
Price: $39.65
Updated: 2024/03/01

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5-Chlorothiophene-2-sulfonyl chloride Chemical Properties,Usage,Production

Chemical Properties

5-Chlorothiophene-2-sulfonyl chloride is white to yellow crystalline low melting solid

Uses

5-Chloro-2-thiophenesulfonyl Chloride is a sulfonylthiophene derivative used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.

Uses

5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.

Synthesis Reference(s)

Tetrahedron, 21, p. 1333, 1965 DOI: 10.1016/S0040-4020(01)98293-6

General Description

5-Chlorothiophene-2-sulfonyl chloride can be prepared from 2-chlorothiophene by reacting with chlorosulfonic acid in the presence of phosphorus pentachloride.

5-Chlorothiophene-2-sulfonyl chloride Preparation Products And Raw materials

Raw materials

2-Chlorothiophene Chlorosulfonic acid Phosphorus pentachloride Diethyl ether

Preparation Products

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5-Chlorothiophene-2-sulfonyl chloride Suppliers

Americas 1 Belgium 4 Canada 1 China 158 Europe 4 Finland 1 France 3 Germany 9 India 12 Japan 5 Russia 2 Slovakia 2 Switzerland 4 Ukraine 2 United Kingdom 22 United States 38 Global 268

Jiaxing Xinrui Pharmaceutical Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Energy Chemical

Tel: 021-021-58432009 400-005-6266
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
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Capot Chemical Co., Ltd

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Email: sales@capotchem.com
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ProdList: 18207
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View Lastest Price from 5-Chlorothiophene-2-sulfonyl chloride manufacturers

Career Henan Chemical Co

Product: 5-Chlorothiophene-2-sulfonyl chloride 2766-74-7
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customise
Release date: 2018-08-09

2766-74-7, 5-Chlorothiophene-2-sulfonyl chlorideRelated Search:

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TIMTEC-BB SBB003378

5-Chlorothiophene-2-sulfonyl chloride 96%

5-CHLORO-2-THIENYLSULFONYL CHLORIDE

5-CHLORO-2-THIOPHENESULFONYL CHLORIDE

5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE

5-CHLOROTHIOPHENE-2-SULPHONYL CHLORIDE

5-CHLOROTHIOPHENESULPHONYL CHLORIDE

ART-CHEM-BB B019398

BUTTPARK 27\04-09

AKOS B019398

5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE, 9

5-Chlorothiophene-2-sulfonylchloride,97%

5-chlorothiophene-2-sulfonyl

5-CHLOROTHIOPHENESULFONYLCHLORIDE,96%

5-chlorothiophene-2-sulfonyl chloride(SALTDATA: FREE)

5-Fluoro,2-sulfonyl chloride thiophene

2-Chloro-5-(chlorosulphonyl)thiophene

5-Chlorothiophen-2-sulfonyl chloride

5-Chlorothiophene-2-sulfonyl chloride ,98%

5-Chlorothiophene-2-sulfonic acid chloride

5-Chlorothiophenesulphonyl chloride,96%

5-Chlloro-2-thiophenesulfonyl Chloride

5-Chloro-2-thiophenesulfonyl Chloride &gt

2-Thiophenesulfonyl chloride, 5-chloro-

2766-74-7

2766-74-4

C4H2Cl2O2S2

C4H2O2Cl2S2

C4H2O2S2Cl2

C4H2Cl2S2O2

Building Blocks

Heterocyclic Building Blocks

Halogenated Heterocycles

Thiophenes

Building Blocks

C4 to C6

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Heterocycle-oher series

Halogenated Heterocycles

Heterocyclic Building Blocks

Thiophenes

ThiophenesBuilding Blocks

Thiophene&Benzothiophene

Thiophene intermediates

Heterocycles