ChemicalBook > CAS DataBase List > STACHYDRINE HYDROCHLORIDE

STACHYDRINE HYDROCHLORIDE

Product Name
STACHYDRINE HYDROCHLORIDE
CAS No.
4136-37-2
Chemical Name
STACHYDRINE HYDROCHLORIDE
Synonyms
StachydrineHCl;Stachydrine chloride;Stachydrine hydrochL;Herba leonurl extract;Cadabine hydrochloride;Stachydrine hydrochlori;Stachytine hydrochloride;Stachydrine hydrichloride;STACHYDRINE HYDROCHLORIDE;Hydrochloric acid Stachydrine
CBNumber
CB4290780
Molecular Formula
C7H14ClNO2
Formula Weight
179.64
MOL File
4136-37-2.mol
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STACHYDRINE HYDROCHLORIDE Property

Melting point:
225°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble in water
Merck 
14,8771
Stability:
Hygroscopic
CAS DataBase Reference
4136-37-2(CAS DataBase Reference)
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Safety

Risk Statements 
20-22
Safety Statements 
22-45-36/37/39
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89799
Product name
Stachydrine chloride
Purity
phyproof? Reference Substance
Packaging
25MG
Price
$286
Updated
2024/03/01
TCI Chemical
Product number
S0358
Product name
Stachydrine Hydrochloride
Packaging
10mg
Price
$31
Updated
2024/03/01
Cayman Chemical
Product number
20506
Product name
Stachydrine (hydrochloride)
Packaging
100mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
20506
Product name
Stachydrine (hydrochloride)
Packaging
1g
Price
$365
Updated
2024/03/01
Cayman Chemical
Product number
20506
Product name
Stachydrine (hydrochloride)
Packaging
250mg
Price
$139
Updated
2024/03/01
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STACHYDRINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Stachydrine Chloride is a constituent of the Chinese herb leonurus heterophyllus sweet. its used in clinics to support blood circulation and dispel blood stasis.

Biological Activity

stachydrine is an anti-metastatic agent.stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of c. leonurus, and many other asian plants and fruits.

in vitro

the aim of a previous study was to investigate the effects of stachydrine (sta) on norepinephrine (ne) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. results showed that ne treatment could increase protein synthesis, cell surface area, the expression level of β-mhc and β/α-mhc ratio and these effects were attenuated by sta treatment. in addition, ne-induced hypertrophy was associated with accelerated decay of ca2+-transient, increased phospholamban expression, increased ca2+-transient amplitude, hyper-phosphorylation, increased intracellular camp level, as well as pka overactivation. all of these effects could be inhibited by sta treatment significantly [1].

in vivo

previous study evaluated the effect of stachydrine on the expression of caspase-9 and 12 in rats with unilateral ureteral obstruction. results showed that degree of renal interstitial fibrosis, serum creatinine, blood urea nitrogen, the renal tubular interstitial damage index, and expression of caspase-9 and 12 in the stachydrine-treatment groups were significantly decreased [2].

target

IL Receptor | T-bet | RORγt | GATA-3 | Foxp3

References

[1] zhang, c. ,shan, x.-l.,liao, y.-l., et al. effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. bmc complement. altern. med. 14, 474 (2014).
[2] zhang c, lu y, zhou yj, tong qq, qu c, kang tj. the effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction. j urol. 2014 nov;192(5):1549-54.

STACHYDRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from STACHYDRINE HYDROCHLORIDE manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Stachydrine hydrochloride 4136-37-2
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98% HPLC
Supply Ability
1000KG
Release date
2022-09-30
Hebei Duling International Trade Co. LTD
Product
Stachytine hydrochloride 4136-37-2
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-05-15
Hebei Yanxi Chemical Co., Ltd.
Product
Stachydrine hydrochloride 4136-37-2
Price
US $40.00-40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-08

4136-37-2, STACHYDRINE HYDROCHLORIDERelated Search:

Evodiamine lithospermic acid B Schisandrin A Motherwort Herb P.E Motherwort Extract Betaine hydrochloride 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Berberine hydrochloride SANGUINARINE Ligustrazine Hydrochloride JATRORRHIZINE HCL(RG) Coptisine chloride CUCURBITACIN IIA 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride Pirenzepine hydrochloride Rimantadine hydrochloride FLUOXETINE HYDROCHLORIDE Robenidine hydrochloride

  • STACHYDRINE HYDROCHLORIDE
  • (S)-2-carboxy-1,1-dimethylpyrrolidinium chloride
  • StachydrineHCl
  • Stachydrine hydrichloride
  • 2-Carboxy-1,1-dimethylpyrrolidinium chloride
  • Stachydrine chloride
  • Stachydrine hydrochlori
  • Stachydrine chloride 2-Carboxy-1,1-dimethylpyrrolidinium chloride
  • Stachydrine hydrochloride, froM Leonurus japonicus
  • Hydrochloric acid Stachydrine
  • Stachydrine hydrochloride, 98%, from Leonurus japonicus
  • Herba leonurl extract
  • Stachydrine hydrochloride, 98%, from Leonurus artemisia (Lour.) S. Y. Hu
  • Stachytine hydrochloride
  • Stachydrine hydrochL
  • Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride, (S)-
  • STACHYDRINE HYDROCHLORIDE CAS : 4136-37-2
  • (S)-2-Carboxy-1,1-dimethylpyrrolidin-1-ium chloride
  • Cadabine hydrochloride
  • 4136-37-2
  • C7H13NO2HCl
  • Ammonium Chlorides (Quaternary)
  • Quaternary Ammonium Compounds
  • Ammonium Chlorides (Quaternary)
  • Quaternary Ammonium Compounds