STACHYDRINE HYDROCHLORIDE
- Product Name
- STACHYDRINE HYDROCHLORIDE
- CAS No.
- 4136-37-2
- Chemical Name
- STACHYDRINE HYDROCHLORIDE
- Synonyms
- StachydrineHCl;Stachydrine chloride;Stachydrine hydrochL;Herba leonurl extract;Cadabine hydrochloride;Stachydrine hydrochlori;Stachydrine chloride-RM;Stachytine hydrochloride;Stachydrine hydrichloride;STACHYDRINE HYDROCHLORIDE
- CBNumber
- CB4290780
- Molecular Formula
- C7H14ClNO2
- Formula Weight
- 179.64
- MOL File
- 4136-37-2.mol
STACHYDRINE HYDROCHLORIDE Property
- Melting point:
- 225°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble in water
- Merck
- 14,8771
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 4136-37-2(CAS DataBase Reference)
Safety
- Risk Statements
- 20-22
- Safety Statements
- 22-45-36/37/39
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHL89799
- Product name
- Stachydrine chloride
- Purity
- phyproof? Reference Substance
- Packaging
- 25MG
- Price
- $286
- Updated
- 2024/03/01
- Product number
- S0358
- Product name
- Stachydrine Hydrochloride
- Packaging
- 10mg
- Price
- $31
- Updated
- 2024/03/01
- Product number
- 20506
- Product name
- Stachydrine (hydrochloride)
- Packaging
- 100mg
- Price
- $63
- Updated
- 2024/03/01
- Product number
- 20506
- Product name
- Stachydrine (hydrochloride)
- Packaging
- 1g
- Price
- $365
- Updated
- 2024/03/01
- Product number
- 20506
- Product name
- Stachydrine (hydrochloride)
- Packaging
- 250mg
- Price
- $139
- Updated
- 2024/03/01
STACHYDRINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Stachydrine Chloride is a constituent of the Chinese herb leonurus heterophyllus sweet. its used in clinics to support blood circulation and dispel blood stasis.
Biological Activity
stachydrine is an anti-metastatic agent.stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of c. leonurus, and many other asian plants and fruits.
in vitro
the aim of a previous study was to investigate the effects of stachydrine (sta) on norepinephrine (ne) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. results showed that ne treatment could increase protein synthesis, cell surface area, the expression level of β-mhc and β/α-mhc ratio and these effects were attenuated by sta treatment. in addition, ne-induced hypertrophy was associated with accelerated decay of ca2+-transient, increased phospholamban expression, increased ca2+-transient amplitude, hyper-phosphorylation, increased intracellular camp level, as well as pka overactivation. all of these effects could be inhibited by sta treatment significantly [1].
in vivo
previous study evaluated the effect of stachydrine on the expression of caspase-9 and 12 in rats with unilateral ureteral obstruction. results showed that degree of renal interstitial fibrosis, serum creatinine, blood urea nitrogen, the renal tubular interstitial damage index, and expression of caspase-9 and 12 in the stachydrine-treatment groups were significantly decreased [2].
target
IL Receptor | T-bet | RORγt | GATA-3 | Foxp3
References
[1] zhang, c. ,shan, x.-l.,liao, y.-l., et al. effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. bmc complement. altern. med. 14, 474 (2014).
[2] zhang c, lu y, zhou yj, tong qq, qu c, kang tj. the effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction. j urol. 2014 nov;192(5):1549-54.
STACHYDRINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
STACHYDRINE HYDROCHLORIDE Suppliers
View Lastest Price from STACHYDRINE HYDROCHLORIDE manufacturers
- Product
- Stachydrine Hydrochloride 4136-37-2
- Price
- US $79.00-38.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-11-21
- Product
- Stachydrine hydrochloride 4136-37-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- ≥98% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-30
- Product
- Stachydrine hydrochloride 4136-37-2
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-08