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TOXIN II, ANEMONIA SULCATA

Product Name
TOXIN II, ANEMONIA SULCATA
CAS No.
60748-45-0
Chemical Name
TOXIN II, ANEMONIA SULCATA
Synonyms
Av2;As2;ATX II;rATX II;Toxin ATX-II;Neurotoxin 2;ANEMONE TOXIN II;seaanemonetoxinii;Anemonia Toxin II;Anemonia viridis toxin 2
CBNumber
CB4305343
Molecular Formula
C213H329N63O61S6
Formula Weight
4940.66686
MOL File
60748-45-0.mol
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TOXIN II, ANEMONIA SULCATA Property

storage temp. 
−20°C
form 
lyophilized powder
Sequence
Gly-Val-Pro-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Ile-Ile-Trp-Leu-Ala-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Lys-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln (Disulfide bonds: Cys4-Cys44, Cys6-Cys34, Cys27-Cys45)
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Safety

WGK Germany 
3
RTECS 
CK4438200
Toxicity
LD50 ivn-mus: 310 mg/kg TOXIA6 16,561,78
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015571
Product name
TOXIN II-ANEMONIA SULCATA
Purity
95.00%
Packaging
100μG
Price
$555.04
Updated
2021/12/16
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TOXIN II, ANEMONIA SULCATA Chemical Properties,Usage,Production

Uses

ATX-II is a specific Na+ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na+Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation[1][2].

Safety Profile

A deadly poison by intravenousand parenteral routes.

References

[1] Fletcher JE, et al. ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine. Anesthesiology. 1999 May;90(5):1294-301. DOI:10.1097/00000542-199905000-00012
[2] Lu YY, et al. ATX-II-induced pulmonary vein arrhythmogenesis related to atrial fibrillation and long QT syndrome. Eur J Clin Invest. 2012 Aug;42(8):823-31. DOI:10.1111/j.1365-2362.2012.02655.x

TOXIN II, ANEMONIA SULCATA Preparation Products And Raw materials

Raw materials

Preparation Products

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TOXIN II, ANEMONIA SULCATA Suppliers

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60748-45-0, TOXIN II, ANEMONIA SULCATARelated Search:


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  • Anemonia viridis toxin 2
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  • Toxin II, Anemonia sulcata - CAS 60748-45-0 - Calbiochem
  • seaanemonetoxinii
  • Anemonia sulcata toxin II
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  • Ion Channels
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  • Cell Biology
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