Azido-PEG9-acid
- Product Name
- Azido-PEG9-acid
- CAS No.
- 1670249-37-2
- Chemical Name
- Azido-PEG9-acid
- Synonyms
- N3-PEG9-COOH;Azido-PEG9-acid;N3-PEG9-CH2CH2COOH;Azido-PEG9-CH2CH2COOH;1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid;N3-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-;3-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber
- CB43062373
- Molecular Formula
- C21H41N3O11
- Formula Weight
- 511.57
- MOL File
- 1670249-37-2.mol
Azido-PEG9-acid Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
Safety
- HS Code
- 2929900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BIPG1110
- Product name
- Azido-PEG9-acid
- Packaging
- 50mg
- Price
- $166
- Updated
- 2021/12/16
- Product number
- CS-0108196
- Product name
- Azido-PEG9-acid
- Packaging
- 250mg
- Price
- $202
- Updated
- 2021/12/16
- Product number
- BP-21825
- Product name
- Azido-PEG9-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- BIPG1110
- Product name
- Azido-PEG9-acid
- Packaging
- 100mg
- Price
- $283
- Updated
- 2021/12/16
- Product number
- BP-21825
- Product name
- Azido-PEG9-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $390
- Updated
- 2021/12/16
Azido-PEG9-acid Chemical Properties,Usage,Production
Description
Azido-PEG9-acid is a PEG molecule consisting of an azide and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU).
Uses
Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Non-cleavable Linker
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG9-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG9-acid Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from Azido-PEG9-acid manufacturers
- Product
- 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid 1670249-37-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- azido-PEG9-Acid 1670249-37-2
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23