Dde Biotin-PEG4-Alkyne
- Product Name
- Dde Biotin-PEG4-Alkyne
- CAS No.
- 1802908-00-4
- Chemical Name
- Dde Biotin-PEG4-Alkyne
- Synonyms
- Dde Biotin-PEG4-Alkyne;Biotin-peg(4)-dde-alkyne;Dde Biotin-PEG4-alkyne Dde;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl]hexahydro-2-oxo-, (3aR,4R,6aS)-rel-
- CBNumber
- CB43062469
- Molecular Formula
- C32H50N4O8S
- Formula Weight
- 650.83
- MOL File
- 1802908-00-4.mol
Dde Biotin-PEG4-Alkyne Property
- Boiling point:
- 880.0±65.0 °C(Predicted)
- Density
- 1.173±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Solid
- pka
- 13.90±0.40(Predicted)
- color
- Brown to reddish brown
N-Bromosuccinimide Price
- Product number
- BP-22679
- Product name
- DdeBiotin-PEG4-alkyne
- Purity
- 95%
- Packaging
- 5mg
- Price
- $239
- Updated
- 2021/12/16
- Product number
- PEG7980
- Product name
- Biotin-PEG(4)-Dde-Alkyne
- Packaging
- 10mg
- Price
- $337.5
- Updated
- 2021/12/16
- Product number
- PEG7980
- Product name
- Biotin-PEG(4)-Dde-Alkyne
- Packaging
- 25mg
- Price
- $560.25
- Updated
- 2021/12/16
- Product number
- PEG7980
- Product name
- Biotin-PEG(4)-Dde-Alkyne
- Packaging
- 100mg
- Price
- $1687.5
- Updated
- 2021/12/16
Dde Biotin-PEG4-Alkyne Chemical Properties,Usage,Production
Description
Dde Biotin-PEG4-alkyne is useful for introducing a biotin moiety to azide-containing molecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine.
Uses
Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Dde Biotin-PEG4-Alkyne Preparation Products And Raw materials
Raw materials
Preparation Products
Dde Biotin-PEG4-Alkyne Suppliers
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
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- 20405
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
View Lastest Price from Dde Biotin-PEG4-Alkyne manufacturers
- Product
- Dde Biotin-PEG4-alkyne 1802908-00-4
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >99.00%
- Supply Ability
- 50mg
- Release date
- 2024-03-21