Description Discovery Glucoraphanin in broccoli
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GLUCORAPHANIN

Description Discovery Glucoraphanin in broccoli
Product Name
GLUCORAPHANIN
CAS No.
21414-41-5
Chemical Name
GLUCORAPHANIN
Synonyms
Gucoraphanin;GLUCORAPHANIN;Glucoraphanin Powder;GLUCORAPHANIN USP/EP/BP;Sulforaphane glucosinolate;GLUCORAPHANIN POTASSIUM SALT(P);Glucoraphanin potassium salt-RM;GLUCORAPHANIN POTASSIUM SALT(RG);GLUCORAPHANIN POTASSIUM SALT(SH);4-METHYLSULFINYLBUTYLGLUCOSINOLATE
CBNumber
CB4313281
Molecular Formula
C12H23NO10S3
Formula Weight
437.51
MOL File
21414-41-5.mol
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GLUCORAPHANIN Property

Density 
1.78±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
White solid.
pka
-2.93±0.18(Predicted)
color 
White to light yellow
InChI
InChI=1/C12H23NO10S3/c1-25(18)5-3-2-4-8(13-23-26(19,20)21)24-12-11(17)10(16)9(15)7(6-14)22-12/h7,9-12,14-17H,2-6H2,1H3,(H,19,20,21)/b13-8+/t7-,9-,10+,11-,12+,25?/s3
InChIKey
GMMLNKINDDUDCF-AAFOYFHQNA-N
SMILES
[C@@H]1(S/C(/CCCCS(C)=O)=N/OS(O)(=O)=O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |&1:0,17,20,22,24,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10009445
Product name
Glucoraphanin
Purity
≥95%
Packaging
1mg
Price
$25
Updated
2021/12/16
Cayman Chemical
Product number
10009445
Product name
Glucoraphanin
Purity
≥95%
Packaging
5mg
Price
$113
Updated
2021/12/16
Cayman Chemical
Product number
10009445
Product name
Glucoraphanin
Purity
≥95%
Packaging
10mg
Price
$199
Updated
2021/12/16
Usbiological
Product number
361796
Product name
Glucoraphanin
Packaging
5mg
Price
$389
Updated
2021/12/16
TRC
Product number
G450250
Product name
Glucoraphanin
Packaging
1mg
Price
$185
Updated
2021/12/16
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GLUCORAPHANIN Chemical Properties,Usage,Production

Description

Glucoraphanin is a glucosinolate found in broccoli, cauliflower, and mustard. Glucoraphanin is converted to sulforaphane by the enzyme myrosinase. In plants, sulforaphane deters insect predators and acts as a selective antibiotic. In humans, sulforaphane has been studied for its potential affects in neurodegenerative and cardiovascular diseases. Due to the potential health benefits, a variety of broccoli has been bred to contain two to three times more glucoraphanin than standard broccoli.

Discovery

In the early 1990’s, scientists at Johns Hopkins University (JHU) identified a compound derived from broccoli called glucoraphanin [2]. Glucoraphanin acts as part of the plant’s defense system. In fact, once converted to its bioactive form, sulforaphane, it is responsible for the characteristic sulfur smell/taste of broccoli. Glucoraphanin belongs to a category of compounds called glucosinolates, which are naturally found in cruciferous vegetables –with broccoli being the king of glucoraphanin. It is converted into sulforaphane by an enzyme found in broccoli called myrosinase or, if this enzyme is deactivated through the cooking process, the body's gut microflora will perform the conversion.

Glucoraphanin in broccoli

Glucoraphanin is a powerful and long-lasting antioxidant, found primarily in broccoli. However, the amount varies tremendously from one broccoli plant to another with no way for consumers to tell how much glucoraphanin is in the broccoli they buy. It has also been shown that this phytonutrient is present in much higher concentrations in the broccoli seeds and 3-day old broccoli sprouts. Brassica created TrueBroc® glucoraphanin from broccoli seeds in order to provide consumers with a concentrated source of glucoraphanin that contains consistent and meaningful levels. Glucoraphanin belongs to a category of compounds called glucosinolates which are naturally found in cruciferous vegetables. Glucosinolates are enzymatically converted into isothiocyanates, which are active in the body. This enzymatic conversion is performed by myrosinase, which is also found naturally in cruciferous vegetables.
Bioavailability studies indicate that glucoraphanin can be absorbed intact, but when eaten within broccoli it is primarily converted to sulforaphane during chewing, which is then absorbed in the upper intestine. Intact glucoraphanin can also be converted to sulforaphane by gut microflora (Holst & Williamson, 2004)

Uses

Glucoraphanin is a natural glycoinsolate found in cruciferous vegetables. Glucophanin (Sulforaphane), is a bioactive component in brocolli and is digested by gut bacteria to produce chemopreventive agents.

Definition

ChEBI: A thia-glucosinolic acid that is glucoerucin in which the sulfur atom of the methyl thioether group has been oxidised to the corresponding sulfoxide.

GLUCORAPHANIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GLUCORAPHANIN manufacturers

Hangzhou Lin'an tianhong biotechnology co.,ltd.
Product
Glucoraphanin 13% 21414-41-5
Price
US $0.00/kg
Min. Order
1kg
Purity
13
Supply Ability
1
Release date
2024-07-26
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Glucoraphanin Powder 21414-41-5
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-18
Wuhan Haorong Biotechnology Co.,Ltd
Product
GLUCORAPHANIN 21414-41-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000
Release date
2023-08-07

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