ChemicalBook > CAS DataBase List > 2-Bromo-5-cyanopyridine

2-Bromo-5-cyanopyridine

Product Name: 2-Bromo-5-cyanopyridine
CAS No.: 139585-70-9
Chemical Name: 2-Bromo-5-cyanopyridine
Synonyms: 2-Br-5-CN-pyridine;6-BroMonicotinitrile;6-Bromo-3-cynopyridine;2-BROMO-5-CYNOPYRIDINE;2-BROMO-5-CYANOPYRIDINE;6-BROMO-NICOTINONITRILE;5-Cyano-2-bromopyridine;6-Bromonicotinonitrile 95%;2-Bromo-5-cyanopyridine 97%;2-Bromo-5-cyanopyridine >
CBNumber: CB4315452
Molecular Formula: C6H3BrN2
Formula Weight: 183.01
MOL File: 139585-70-9.mol

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2-Bromo-5-cyanopyridine Property

Melting point:: 136-140
Boiling point:: 261.6±20.0 °C(Predicted)
Density: 1.72±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
pka: -2.66±0.10(Predicted)
color: White to Yellow to Orange
CAS DataBase Reference: 139585-70-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-41-37/38-22
Safety Statements: 26-36/37/39-39-24/25
RIDADR: 3439
WGK Germany: 3
Hazard Note: Irritant/Keep Cold
HazardClass: IRRITANT
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS003693
Product name: 2-bromo-5-cyanopyridine
Purity: AldrichCPR
Packaging: 250mg
Price: $70.9
Updated: 2024/03/01

TCI Chemical

Product number: B4039
Product name: 2-Bromo-5-cyanopyridine
Purity: >97.0%(GC)
Packaging: 1g
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: B4039
Product name: 2-Bromo-5-cyanopyridine
Purity: >97.0%(GC)
Packaging: 5g
Price: $124
Updated: 2025/07/31

TRC

Product number: B682833
Product name: 2-Bromo-5-cyanopyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B682833
Product name: 2-Bromo-5-cyanopyridine
Packaging: 1g
Price: $75
Updated: 2021/12/16

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2-Bromo-5-cyanopyridine Chemical Properties,Usage,Production

Chemical Properties

White to yellow crystalline solid

Uses

6-Bromonicotinonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis Reference(s)

The Journal of Organic Chemistry, 66, p. 1500, 2001 DOI: 10.1021/jo005682n

Synthesis

33252-28-7

139585-70-9

The general procedure for the synthesis of 2-bromo-5-cyanopyridine from 2-chloro-5-cyanopyridine is as follows: Example 29 Synthesis of 6-bromonicotinonitrile. 6-Chloronicotinonitrile (13.8 g, 100 mmol) was mixed with phosphorus tribromide (150 mL) and the reaction was heated at 145°C for 32 hours. After completion of the reaction, the mixture was cooled and concentrated in vacuum. To the concentrated residue, phosphorus tribromide (150 mL) was added again and the reaction was heated at 145°C for 32 hours. At the end of the reaction, the mixture was cooled and concentrated under vacuum. The concentrated residue was slowly added to an ice-water mixture (500 mL) and the reaction mixture was neutralized with sodium bicarbonate. Subsequently, the product was extracted with ethyl acetate (3 x 250 mL). The organic phases were combined, washed with saturated brine and dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure and the residue was purified by column chromatography (eluent: hexane-ethyl acetate) to afford 14.9 g (81% yield) of 6-bromonicotinonitrile as a white solid. The product was characterized as follows: 1H NMR (400 MHz, CDCl3) δ 7.66 (d, J = 11.0 Hz, 1H), 7.80 (dd, J = 3.1, 11.0 Hz, 1H), 8.67 (d, J = 3.1 Hz, 1H); mass spectra (M + H)+ m/z = 183.0, 185.0.

References

[1] Patent: US2005/192302, 2005, A1. Location in patent: Page/Page column 30
[2] Patent: WO2012/114223, 2012, A1. Location in patent: Page/Page column 56
[3] Journal of Organic Chemistry, 2001, vol. 66, # 4, p. 1500 - 1502

2-Bromo-5-cyanopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Bromo-5-cyanopyridine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Bromo-5-cyanopyridine 139585-70-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Dideu Industries Group Limited

Product: 2-Bromo-5-cyanopyridine 139585-70-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-14

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-5-cyanopyridine 139585-70-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

139585-70-9, 2-Bromo-5-cyanopyridineRelated Search:

2-Bromo-5-hydroxypyridine 3-Bromo-5-cyanopyridine 97%,3-BROMO-5-CYANOPYRIDINE,5-BROMO-3-CYANOPYRIDINE 5-BROMO-2-CYANOPYRIDINE,2-CYANO-5-BROMOPYRIDINE / 5-BROMO-2-CYANOPYRIDINE,5-Bromo-2-cyanopyridine 97% 3-BROMO-2-CYANOPYRIDINE,2-Bromo-3-cyanopyridine ,3-Bromo-2-cyanopyridine 97+% 3-BROMO-4-CYANOPYRIDINE 4-BROMO-3-CYANOPYRIDINE 2,6-Dibromo-4-cyanopyridine 2-Bromo-4-cyanopyridine 2-Bromo-5-cyanopyridine 4-BROMO-2-CYANOPYRIDINE 2-BROMO-6-CYANOPYRIDINE,6-Bromo-2-cyanopyridine 3-Cyanopyridine 3-Cyano-4,6-dibromo-2-methyl-5-phenylpyridine 2-Bromo-5-cyano-3-picoline 2-BROMO-5-CYANO-6-PICOLINE 2-Amino-3-bromo-5-cyanopyridine 6-Amino-3-bromo-2-cyanopyridine 5-BROMO-6-CYANOPYRIDINE-2-CARBOXYLIC ACID

6-BroMonicotinitrile

5-(4-tetrahydropyranyl)-1,3-dibromobenzene

6-Bromonicotinonitrile 95%

3-PYRIDINECARBONITRILE, 6-BROMO-

6-BROMO-NICOTINONITRILE

2-Bromo-5-cyanopyridine, 6-Bromopyridine-3-carbonitrile

6-Bromopyridine-3-carbonitrile

6-broMopyridin-3-carbonitrile

2-Br-5-CN-pyridine

2-BROMO-5-CYANOPYRIDINE

6-Bromo-3-cynopyridine

2-Bromo-5-cyanopyridine 97%

2-Bromo-5-pyridinecarbonitrile

2-Bromo-5-cyanopyridine≥ 98.5% (HPLC)

5-Cyano-2-bromopyridine

2-BROMO-5-CYNOPYRIDINE

5-cyanopyridine Other Name 6-Bromonicotinonitrile

2-Bromo-5-cyanopyridine &gt

6-Bromo-3-pyridinecarbonitrile

2-Bromo-5-cyanopyridine ISO 9001：2015 REACH

6-Bromo-3-cyano pyrdine [2-Bromo-5-cyanopyridine]

139585-70-9

139585-70-1

Benzothiazoles

Pyridine series

Halides

Boron, Nitrile, Thio,& TM-Cpds

Heterocycles

blocks

Bromides

Carboxes

Pyridines

Pyridine