5-Bromonicotinonitrile
- Product Name
- 5-Bromonicotinonitrile
- CAS No.
- 35590-37-5
- Chemical Name
- 5-Bromonicotinonitrile
- Synonyms
- 5-Bromocyanine;BUTTPARK 29\04-94;AKOS BBS-00003122;IFLAB-BB F2124-0063;5-Bromonicotinitrile;5-BROMONICOTINONITRILE;3-Cyano-5-broMopyridine;3-BROMO-5-CYANOPYRIDINE;5-BROMO-3-CYANOPYRIDINE;5-Bromonicotinonitrile 97%
- CBNumber
- CB9197831
- Molecular Formula
- C6H3BrN2
- Formula Weight
- 183.01
- MOL File
- 35590-37-5.mol
5-Bromonicotinonitrile Property
- Melting point:
- 103-107 °C(lit.)
- Boiling point:
- 228.8±20.0 °C(Predicted)
- Density
- 1.72±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Heated), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -0.57±0.20(Predicted)
- color
- Pale Yellow to Yellow
- InChI
- InChI=1S/C6H3BrN2/c7-6-1-5(2-8)3-9-4-6/h1,3-4H
- InChIKey
- FTFFHWWIPOQCBC-UHFFFAOYSA-N
- SMILES
- C1=NC=C(Br)C=C1C#N
- CAS DataBase Reference
- 35590-37-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- RIDADR
- 3276
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 574422
- Product name
- 5-Bromo-3-cyanopyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $52.2
- Updated
- 2023/06/20
- Product number
- B3713
- Product name
- 5-Bromo-3-pyridinecarbonitrile
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $34
- Updated
- 2025/07/31
- Product number
- B3713
- Product name
- 5-Bromo-3-pyridinecarbonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $99
- Updated
- 2025/07/31
- Product number
- B682750
- Product name
- 3-Bromo-5-cyanopyridine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B2848-09A
- Product name
- 3-Bromo-5-cyanopyridine
- Packaging
- 1g
- Price
- $326
- Updated
- 2021/12/16
5-Bromonicotinonitrile Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Synthesis
625-92-3
35590-37-5
General procedure for the synthesis of 3-cyano-5-bromopyridine from 3,5-dibromopyridine: iPrMgCl (2M in THF, 4.1 mL) and THF (5 mL) were added to a flask containing dry LiCl (0.35 g, 8.24 mmol) at 15 °C. After stirring for 15 min, a solution of 3-bromo-1-benzylnitrile (1.46 g, 8.03 mmol) in THF (1 mL) was slowly added to the reaction mixture and stirring was continued for 15 min. Subsequently, DMF (1.3 mL, 12 mmol) was added dropwise at 0 °C and the mixture was stirred for 2 hours. Upon completion of the reaction, aqueous NH3 (7 mL, 28-30%) and I2 (4.06 g, 16 mmol) were added to the mixture. After stirring for 2 h at room temperature, the reaction mixture was poured into saturated aqueous Na2SO3 solution and extracted with CHCl3 (3 x 30 mL). The organic layers were combined, dried with Na2SO4 and filtered. After removing the solvent under reduced pressure, the residue was purified by silica gel short column chromatography (eluent: hexane/ethyl acetate = 9:1, v/v) to afford pure 3-cyano-5-bromopyridine (0.73 g) in 71% yield. Most of the nitrile compounds involved in this study were commercially available and were identified by comparison with real samples.
References
[1] Tetrahedron, 2013, vol. 69, # 5, p. 1462 - 1469
5-Bromonicotinonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Bromonicotinonitrile manufacturers
- Product
- 5-Bromonicotinonitrile 35590-37-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-10-18
- Product
- 5-Bromonicotinonitrile 35590-37-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-22
- Product
- 5-Bromonicotinonitrile 35590-37-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-18