ChemicalBook > CAS DataBase List > Fmoc-Asn(Trt)-OH

Fmoc-Asn(Trt)-OH

Product Name
Fmoc-Asn(Trt)-OH
CAS No.
132388-59-1
Chemical Name
Fmoc-Asn(Trt)-OH
Synonyms
FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
CBNumber
CB4331632
Molecular Formula
C38H32N2O5
Formula Weight
596.67
MOL File
132388-59-1.mol
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Fmoc-Asn(Trt)-OH Property

Melting point:
201-204 °C(lit.)
Boiling point:
858.1±65.0 °C(Predicted)
alpha 
-16 º (c=1, MeOH)
Density 
1.271±0.06 g/cm3(Predicted)
refractive index 
-19 ° (C=1, DMF)
storage temp. 
2-8°C
solubility 
<0.00005g/l
pka
3.79±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
optical activity
[α]20/D 15.0±1°, c = 1% in methanol
BRN 
4343823
InChIKey
KJYAFJQCGPUXJY-UUWRZZSWSA-N
SMILES
C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference
132388-59-1(CAS DataBase Reference)
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Safety

Risk Statements 
53
Safety Statements 
24/25-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
3-10
HS Code 
2924 29 70
HazardClass 
IRRITANT
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52044
Product name
FMOC-Asn(Trt)-OH
Purity
N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging
25g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52044
Product name
FMOC-Asn(Trt)-OH
Purity
N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging
100g
Price
$219
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52044
Product name
FMOC-Asn(Trt)-OH
Purity
N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging
250g
Price
$467
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52044
Product name
FMOC-Asn(Trt)-OH
Purity
N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
Packaging
1kg
Price
$1620
Updated
2024/03/01
Sigma-Aldrich
Product number
47672
Product name
Fmoc-Asn(Trt)-OH
Purity
≥97.0%
Packaging
5G
Price
$59.4
Updated
2024/03/01
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Fmoc-Asn(Trt)-OH Chemical Properties,Usage,Production

Description

Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.

Chemical Properties

white crystal powde

Uses

Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.

Preparation

Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.

Fmoc-Asn(Trt)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Asn(Trt)-OH Suppliers

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View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Asn(Trt)-OH 132388-59-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-07
Wuhan Senwayer Century Chemical Co.,Ltd
Product
Fmoc-Asn(trt)-OH 132388-59-1
Price
US $0.00/gram
Min. Order
25gram
Purity
99% HPLC
Supply Ability
25 gram
Release date
2023-10-16
Hangzhou ICH Biofarm Co., Ltd
Product
Fmoc-N-β-trityl-L-asparagine 132388-59-1
Price
US $0.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
200kg
Release date
2023-06-26

132388-59-1, Fmoc-Asn(Trt)-OHRelated Search:


  • N-ALPHA-FMOC-N-GAMMA-TRITYL-L-ASPARAGINE
  • FMOC-ASPARAGINE(TRT)
  • FMOC-ASN(XAN)-OH
  • FMOC-ASN(TRT)-OH
  • FMOC-ASN(TRT)
  • FMOC-L-ASN(TRITYL)
  • FMOC-L-ASN(TRT)-OH
  • FMOC-L-ASPARGINE(TRITYL)
  • FMOC-L-ASPARAGINE(TRITYL)
  • FMOC-L-ASPARAGINE (TRT)
  • FMOC-N-GAMMA-XANTHYL-L-ASPARAGINE
  • Nalpha-fluorenylmethoxycarbonyl-Ngamma-trityl-L-asparagine
  • Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine, Nα-Fmoc-Nγ-trityl-L-asparagine
  • N-(9-Fluorenylmethyloxycarbonyl)-N-trityl-L-asparagine ,98%
  • Fmoc-L-Asparagine(Trt)-OH
  • Fmoc-N-trityl-L-asparagine ,98%
  • Fmoc-N-trityl-L-aspa
  • Fmoc-Asparagine(Trt)-OH
  • L-ASPARAGINE-N-FMOC, N-BETA-TRITYL
  • Nalpha-Fmoc-Ngamma-trityl-L-asparagine Fmoc-Asn(Trt)-OH
  • N^a-FMoc-N^y-trityl-L-asparagine, 97%
  • FMoc-N-trityl-L-aspaD23-Ragine
  • (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-4-oxo-4-(tritylaMino)butanoic acid
  • FMoc-Asn(Tre)
  • Fmoc-Asn(Trt)-OH >=97.0% (sum of enantiomers, HPLC)
  • Fmoc-Asn(Trt)-OH(CAS:132388-59-1)
  • L-Asn(Trt)
  • FMOC-NG-TRITYL-L-ASPARAGINE
  • FMOC-N-GAMMA-TRITYL-L-ASPARAGINE
  • FMOC-N-TRITYL-L-ASPARAGINE
  • FMOC-N-BETA-TRITYL-L-ASPARAGINE
  • N<SUB>α</SUB>-(9-Fluorenylmethoxycarbonyl)-N<SUB>γ</SUB>-trityl-L-asparagine
  • N<SUB>α</SUB>-Fmoc-N<SUB>γ</SUB>-trityl-L-asparagine
  • Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine
  • na-fmoc-N-gamma-trityl-L-asparagine
  • N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit
  • N-α-Fmoc-N-γ-trityl-L-asparagine
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-&
  • FMOC-N-TRITYL-L-ASPARAGINE 97+%
  • N-FMOC-N4-TRITYL-L-ASPARAGINE
  • N-(9-Fluorenylmethoxycarbonyl)-N-trityl-L-aspara
  • L-Asparagine N-|beta|-Trityl-15N2-N-alpha-FMOC
  • L-Asparagin, N(2)-((9H-fluoren-9-ylmethoxy)carbonyl)- N-(triphenylmethyl)-
  • N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-(TRIPHENYLMETHYL)-L-ASPARAGINE
  • N-.ALPHA.-FMOC-N-.GAMMA.-XANTHYL-L-ASPARAGINE
  • N-α-Fmoc-β-trityl-L-asparagine
  • L-Asparagine N-β-Trityl-15N2-N-α-FMOC
  • Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nγ-trityl-L-asparagine
  • Nα-Fmoc-Nγ-trityl-L-asparagine≥ 99.7% (HPLC, Chiral purity)
  • N-FMOC-L-ASN(TRT)-OH
  • N-(9-FLUORENYL METHOXY CARBONYL)-N-TRITYL-L-ASPARAGINE
  • N-ALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-GAMMA-TRITYL-L-ASPARAGINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-BETA-TRITYL-L-ASPARAGINE
  • N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-OMEGA-TRITYL-L-ASPARAGINE
  • NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-NR-TRITYL-L-ASPARAGINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-GAMMA-TRITYL-L-ASPARAGINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA-TRITYL-L-ASPARAGINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA-XANTHYL-L-ASPARAGINE