Fmoc-Asn(Trt)-OH
- Product Name
- Fmoc-Asn(Trt)-OH
- CAS No.
- 132388-59-1
- Chemical Name
- Fmoc-Asn(Trt)-OH
- Synonyms
- FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
- CBNumber
- CB4331632
- Molecular Formula
- C38H32N2O5
- Formula Weight
- 596.67
- MOL File
- 132388-59-1.mol
Fmoc-Asn(Trt)-OH Property
- Melting point:
- 201-204 °C(lit.)
- Boiling point:
- 858.1±65.0 °C(Predicted)
- alpha
- -16 º (c=1, MeOH)
- Density
- 1.271±0.06 g/cm3(Predicted)
- refractive index
- -19 ° (C=1, DMF)
- storage temp.
- 2-8°C
- solubility
- <0.00005g/l
- pka
- 3.79±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- optical activity
- [α]20/D 15.0±1°, c = 1% in methanol
- BRN
- 4343823
- InChIKey
- KJYAFJQCGPUXJY-UUWRZZSWSA-N
- SMILES
- C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
- CAS DataBase Reference
- 132388-59-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 8.52044
- Product name
- FMOC-Asn(Trt)-OH
- Purity
- N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
- Packaging
- 25g
- Price
- $72.8
- Updated
- 2024/03/01
- Product number
- 8.52044
- Product name
- FMOC-Asn(Trt)-OH
- Purity
- N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
- Packaging
- 100g
- Price
- $219
- Updated
- 2024/03/01
- Product number
- 8.52044
- Product name
- FMOC-Asn(Trt)-OH
- Purity
- N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
- Packaging
- 250g
- Price
- $467
- Updated
- 2024/03/01
- Product number
- 8.52044
- Product name
- FMOC-Asn(Trt)-OH
- Purity
- N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem?
- Packaging
- 1kg
- Price
- $1620
- Updated
- 2024/03/01
- Product number
- 47672
- Product name
- Fmoc-Asn(Trt)-OH
- Purity
- ≥97.0%
- Packaging
- 5G
- Price
- $59.4
- Updated
- 2024/03/01
Fmoc-Asn(Trt)-OH Chemical Properties,Usage,Production
Description
Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.
Chemical Properties
white crystal powde
Uses
Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
Preparation
Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.
Fmoc-Asn(Trt)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers
- Product
- Fmoc-L-Asn(Trt)-OH 132388-59-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-12-07
- Product
- Fmoc-Asn(trt)-OH 132388-59-1
- Price
- US $0.00/gram
- Min. Order
- 25gram
- Purity
- 99% HPLC
- Supply Ability
- 25 gram
- Release date
- 2023-10-16
- Product
- Fmoc-N-β-trityl-L-asparagine 132388-59-1
- Price
- US $0.00/Box
- Min. Order
- 1Box
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2023-06-26