Mezlocillin sodium
- Product Name
- Mezlocillin sodium
- CAS No.
- 59798-30-0
- Chemical Name
- Mezlocillin sodium
- Synonyms
- Chebi:52067;MEZLOCILLIN SODIUM;Mezlocillin Baypen;Meloxicillin sodium;Sodium salt monohydrate;Mezlocillin (sodium salt);Mezlocillin Sodium (350 mg);Mezlocillin sodium USP/EP/BP;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate
- CBNumber
- CB4353793
- Molecular Formula
- C22H27N6NaO9S2
- Formula Weight
- 606.6
- MOL File
- 59798-30-0.mol
Mezlocillin sodium Property
- Melting point:
- 197-201°C (dec.)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble in water or DMSO
- CAS DataBase Reference
- 59798-30-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P285In case of inadequate ventilation wear respiratory protection.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- J66306
- Product name
- Mezlocillin sodium salt
- Packaging
- 100mg
- Price
- $215
- Updated
- 2024/03/01
- Product number
- J66306
- Product name
- Mezlocillin sodium salt
- Packaging
- 500mg
- Price
- $515
- Updated
- 2021/12/16
- Product number
- 30691
- Product name
- Mezlocillin (sodium salt)
- Packaging
- 500mg
- Price
- $290
- Updated
- 2024/03/01
- Product number
- 30691
- Product name
- Mezlocillin (sodium salt)
- Packaging
- 1g
- Price
- $547
- Updated
- 2024/03/01
- Product number
- 30691
- Product name
- Mezlocillin (sodium salt)
- Packaging
- 250mg
- Price
- $153
- Updated
- 2024/03/01
Mezlocillin sodium Chemical Properties,Usage,Production
Description
Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.
Chemical Properties
Mezlocillin sodium is white to slightly yellow cryst. powder
Uses
Antibacterial.
Uses
Mezlocillin Sodium (cas# 59798-30-0) is a derivative of penicillin and an antimicrobial.
Definition
ChEBI: Mezlocillin sodium is an organic sodium salt. It contains a mezlocillin(1-).
brand name
Mezlin (Bayer).
Clinical Use
Mezlocillin (Mezlin) is an acylureidopenicillin with an antibacterialspectrum similar to that of carbenicillin andticarcillin; however, there are some major differences. It ismuch more active against most Klebsiella spp., P. aeruginosa,anaerobic bacteria (e.g., Streptococcus faecalis andB. fragilis), and H. influenzae. It is recommended for thetreatment of serious infections caused by these organisms.
Mezlocillin is not generally effective against β-lactamase–producing bacteria, nor is it active orally. It isavailable as a white, crystalline, water-soluble sodium saltfor injection. Solutions should be prepared freshly and, ifnot used within 24 hours, refrigerated. Mezlocillin and otheracylureidopenicillins, unlike carbenicillin, exhibit nonlinearpharmacokinetics. Peak plasma levels, half-life, and areaunder the time curve increase with increased dosage.Mezlocillin has less effect on bleeding time than carbenicillin,and it is less likely to cause hypokalemia.
Mezlocillin sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Mezlocillin sodium manufacturers
- Product
- Mezlocillin Sodium 59798-30-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.912%
- Supply Ability
- 10ton
- Release date
- 2024-04-22
- Product
- Mezlocillin sodium 59798-30-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-06-30
- Product
- Mezlocillin Sodium 59798-30-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2023-03-16