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VASICINONE

Product Name
VASICINONE
CAS No.
486-64-6
Chemical Name
VASICINONE
Synonyms
VASICINONE;l-Vasicinone;Vasicinone-RM;2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3β-hydroxypyrrolo[2,1-b]quinazoline-9(1H)-one;Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-3-hydroxy-, (3S)-
CBNumber
CB4385271
Molecular Formula
C11H10N2O2
Formula Weight
202.21
MOL File
486-64-6.mol
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VASICINONE Property

Melting point:
200-202℃
Boiling point:
320.7°C (rough estimate)
Density 
1.50
refractive index 
1.5300 (estimate)
solubility 
Soluble in chloroform and ethanol;
form 
powder
pka
12.76±0.20(Predicted)
color 
White
Water Solubility 
1.597g/L(25 ºC)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11761
Product name
Vasicinone
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
11761
Product name
Vasicinone
Purity
≥98%
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
11761
Product name
Vasicinone
Purity
≥98%
Packaging
10mg
Price
$283
Updated
2024/03/01
AK Scientific
Product number
W1012
Product name
Vasicinone
Packaging
10mg
Price
$413
Updated
2021/12/16
Crysdot
Product number
CD32001262
Product name
Vasicinone
Purity
95+%
Packaging
5mg
Price
$530
Updated
2021/12/16
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VASICINONE Chemical Properties,Usage,Production

Description

A further alkaloid present in Adhatoda vasica and Peganum harmala, this base forms colourless crystals from 95 per cent EtOH. It has [α]22D - 100° (c 0.5, CHCL3) and the ultraviolet spectrum has absorption maxima at 227, 272, 302 and 315 mfJ.. The alkaloid yields a series of crystalline salts with mineral acids, e.g. the hydrochloride, m.p. 232-4°C; hydro bromide, m.p. 254-5°C (dec.); hydriodide, m.p. 222-6°C (dec.); nitrate, m.p. 138-9° C (dec.) and the sulphate, m.p. l82-5°C (dec.). The optically inactive form of the base has been prepared synthetically, m.p. 211- 2°C. The alkaloid is an active bronchodilator.

Definition

ChEBI: Vasicinone is a member of quinazolines.

target

P450 (e.g. CYP17)

References

Ghose et al., J. Chem. Soc., 2740 (1932)
Morris, Horford, Adams., J. Amer. Chem. Soc., 57,951 (1935)
Mehta, Naravane, Desai., J. Org. Chem., 28, 445 (1963)

VASICINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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VASICINONE Suppliers

kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47

486-64-6, VASICINONERelated Search:


  • VASICINONE
  • (3R)-2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one
  • (3R)-2,3-Dihydro-3β-hydroxypyrrolo[2,1-b]quinazoline-9(1H)-one
  • 2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one
  • l-Vasicinone
  • Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-3-hydroxy-, (3S)-
  • Vasicinone-RM
  • 486-64-6
  • Cl1H10N2O2
  • Alkaloids