RUSCOGENIN

Product Name: RUSCOGENIN
CAS No.: 472-11-7
Chemical Name: RUSCOGENIN
Synonyms: RUSCOGENINE;HeModren;FlebopoM;Ruscogeni;RUSCOGENIN;Rectolander;Ruscorectal;RUSCOGENIN(P);Ruscogenins CRS;RUSCOGENIN USP/EP/BP
CBNumber: CB4411307
Molecular Formula: C27H42O4
Formula Weight: 430.63
MOL File: 472-11-7.mol

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RUSCOGENIN Property

Melting point:: 198-202℃
Boiling point:: 563.1±50.0 °C(Predicted)
Density: 1.18
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka: 14.56±0.70(Predicted)
form: Solid
color: White

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Safety

Safety Statements: 24/25
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 10mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

TRC

Product number: R701750
Product name: Ruscogenin
Packaging: 50mg
Price: $1190
Updated: 2021/12/16

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RUSCOGENIN Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.

Definition

ChEBI: Ruscogenin is a triterpenoid.

Biological Activity

Ruscogenin is a well-known compound for down-regulating nuclear factor kappa B (NF-KB), intercellular adhesion molecule-1 (ICAM-1), tissue factor (TF), inducible NO synthase (iNOS), and modulating inflammatory pathways. It displays anti-inflammatory properties by inhibiting lipopolysaccharide (LPS)-induced acute lung injury (ALI), and improving diabetic nephropathy in in vivo studies. Ruscogenin also exerts neuroprotective properties and protects the brain against ischemic injury in mouse model. It elicits anti-tumor properties by inducing ferroptosis in pancreatic cancer cells in both in vitro and in vivo studies.

target

PGE | TNF-α | NF-kB | p65 | NO | NOS | COX | ERK | JNK | Akt | p38MAPK | PKA | cAMP | IL Receptor

RUSCOGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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RUSCOGENIN Suppliers

Canada 1 China 184 Germany 2 India 4 United Kingdom 3 United States 14 USA 1 Global 209

Pharma Affiliates

Tel: --
Fax: --
Email: @pharmaffiliates.com
Country: India
ProdList: 6754
Advantage: 58

Pharmaffiliates Analytics and Synthetics P. Ltd

Tel: --
Fax: --
Email: mktg@pharmaffiliates.com
Country: India
ProdList: 6739
Advantage: 58

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View Lastest Price from RUSCOGENIN manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: RUSCOGENIN 472-11-7
Price: US $1.00-45.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2000KG
Release date: 2024-08-01

Shanghai Standard Technology Co., Ltd.

Product: Ruscogenin 472-11-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-31

Career Henan Chemical Co

Product: RUSCOGENIN 472-11-7
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

472-11-7, RUSCOGENINRelated Search:

Centella asiatica extract 3-(1,3-Benzodioxol-5-ylmethyl)-3,4-dihydro-5,7-dihydroxy-8-methyl-4-oxo-2H-1-benzopyran-6-carboxaldehyde Ophiopogonanone B Ophiopogonis Extract Diosgenin FORSYTHIN lithospermic acid B AURANTIO-OBTUSIN SENEGENIN Ophiopogonin A RUSCOGENIN NEORUSCOGENIN ophiopogonin B S-Ruscogenin,(25S)-Ruscogenin OPHIOPOGONIN D OPHIOPOGONIN C ruscogenin-1-yl xylopyranosyl-1-3-(glucopyranosyl-1-2)fucopyranoside RUSCOGENIN(PRIMARY STANDARD)

FlebopoM

HeModren

Rectolander

Ruscogenin, froM Ophiopogon japonicus

(1B,3B,25R)-SPIROST-5-ENE-1,3-DIOL

RUSCOGENIN

RUSCOGENINE

(25R)-spirost-5-ene-1-beta,3-beta-diol

Spirost-5-ene-1,3-diol, (1.beta.,3.beta.,25R)-

RUSCOGENIN(P)

(1beta,3beta,25R)-Spirost-5-ene-1,3-diol

(1β,3β,25R)-Spirost-5-ene-1,3-diol

25D-Spirost-5-ene-1β,3β-diol

Ruscogenin, 98%, from Ophiopogon japonicus (Thunb.) Ker Gawl.

(25R)-Spirost-5-ene-1β,3β-diol

Ruscorectal

Ruscogenins CRS

Spirost-5-ene-1,3-diol, (1β,3β,25R)-

RUSCOGENIN USP/EP/BP

Ruscogeni

Ruscogenin (6CI, 7CI)

Ruscogenin, 10 mM in DMSO

472-11-7

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