3-Ethynylaniline
- Product Name
- 3-Ethynylaniline
- CAS No.
- 54060-30-9
- Chemical Name
- 3-Ethynylaniline
- Synonyms
- 3-ETHYNYLANILINE;3-ETHYNYL-PHENYLAMINE;3-EthynylbenzaMine;M-AMINOPHENYL ACETYLENE;SOLI-006;3-Ethynyl;Erlotinib-8;Erlotinib INT;3-Ethynlaniline;m-Ethnylaniline
- CBNumber
- CB4417819
- Molecular Formula
- C8H7N
- Formula Weight
- 117.15
- MOL File
- 54060-30-9.mol
3-Ethynylaniline Property
- Melting point:
- 27°C
- Boiling point:
- 92-93 °C (2 mmHg)
- Density
- 1.04
- refractive index
- 1.614-1.616
- Flash point:
- 138 °F
- storage temp.
- 2-8°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
- pka
- 3.67±0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.12
- color
- Clear yellow to brown
- Water Solubility
- Insoluble in water.
- BRN
- 2935417
- Stability:
- Light Sensitive
- InChIKey
- NNKQLUVBPJEUOR-UHFFFAOYSA-N
- CAS DataBase Reference
- 54060-30-9(CAS DataBase Reference)
- NIST Chemistry Reference
- M-aminophenylacetylene(54060-30-9)
- EPA Substance Registry System
- Benzenamine, 3-ethynyl- (54060-30-9)
Safety
- Hazard Codes
- Xi,F
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39-36/37
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- Ⅲ
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 498289
- Product name
- 3-Ethynylaniline
- Purity
- ≥98%
- Packaging
- 5g
- Price
- $61.2
- Updated
- 2024/03/01
- Product number
- A1122
- Product name
- 3-Ethynylaniline
- Purity
- >98.0%(GC)
- Packaging
- 10g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- A1122
- Product name
- 3-Ethynylaniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $193
- Updated
- 2024/03/01
- Product number
- L20124
- Product name
- 3-Aminophenylacetylene, 98%
- Packaging
- 5g
- Price
- $71.65
- Updated
- 2024/03/01
- Product number
- L20124
- Product name
- 3-Aminophenylacetylene, 98%
- Packaging
- 25g
- Price
- $223.65
- Updated
- 2024/03/01
3-Ethynylaniline Chemical Properties,Usage,Production
Chemical Properties
Clear yellowish to brown liquid
Uses
Reagent in the preparation of a labelled metabolite of Erlotinib (E625000).
Uses
3-Aminophenylacetylene is used as a pharmaceutical intermediate.
Application
3-Ethynylaniline may be used in the synthesis of the following benzoxazine monomers: bis{4-[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yloxy)]phenyl}phenylphosphino-1-one, [3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazaperhydroin-6-yl)][3-(3-ethynylphenyl)(2H,4H-benzo[3,4-e]1,3-oxazin-6-yl)]phenylphosphino-1-one, and bis[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yl)oxy]phenylphosphino-1-one.
It may be used:
To synthesize succin(m-ethynyl)dianilide and sebaco(m-ethynyl)dianilide. As a reagent in the multi-step synthesis of erlotinib hydrochloride. To prepare 3-(3-ethynylphenyl)-6-methyl-2H, 4H-benzo[e]1,3-oxazine. To prepare 3-[3-(4-acetylamino-benzyl)-[1,2,4]oxadiazol-5- yl]-N-(3-ethynyl-phenyl)-propionamide.
General Description
3-Ethynylaniline is a terminal alkyne that can be prepared by the reduction of 3-ethylnylnitrobenzene.
3-Ethynylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
3-Ethynylaniline Suppliers
View Lastest Price from 3-Ethynylaniline manufacturers
- Product
- 3-Ethynylaniline 54060-30-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-16
- Product
- 3-Aminophenylacetylene 54060-30-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%(HPLC)
- Supply Ability
- 2000kg/Year
- Release date
- 2023-12-14
- Product
- 3-Aminophenylacetylene 54060-30-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-09-06