ChemicalBook > CAS DataBase List > Levosulpiride

Levosulpiride

Product Name
Levosulpiride
CAS No.
23672-07-3
Chemical Name
Levosulpiride
Synonyms
Levosulpride;l-Form;rv-12309;Levopride;levopraid;l-Sulpirid;levosupride;l-Sulpiride;LEVOSULPIRIDE;(S)-(-)-Sulpir
CBNumber
CB4422019
Molecular Formula
C15H23N3O4S
Formula Weight
341.43
MOL File
23672-07-3.mol
More
Less

Levosulpiride Property

Melting point:
183-186 °C(lit.)
Density 
1.236±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
9.98±0.60(Predicted)
form 
Solid
color 
White to Off-White
Merck 
14,8989
InChIKey
BGRJTUBHPOOWDU-NSHDSACASA-N
CAS DataBase Reference
23672-07-3(CAS DataBase Reference)
More
Less

Safety

RIDADR 
3077
WGK Germany 
3
RTECS 
BZ3400100
HS Code 
29350090
Toxicity
LD50 oral in rabbit: > 1500mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S7771
Product name
(S)-(?)-Sulpiride
Purity
≥98% (titration)
Packaging
5g
Price
$96.1
Updated
2024/03/01
Sigma-Aldrich
Product number
34002
Product name
(S)-(−)-Sulpiride
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$145
Updated
2024/03/01
Sigma-Aldrich
Product number
5.05626
Product name
(S)-Sulpiride - CAS 23672-07-3 - Calbiochem
Packaging
100mg
Price
$82.2
Updated
2022/05/15
TCI Chemical
Product number
I0821
Product name
(S)-(-)-Sulpiride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
I0821
Product name
(S)-(-)-Sulpiride
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$271
Updated
2024/03/01
More
Less

Levosulpiride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

(S)-(?)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11

Uses

dopamine receptor antagonists

Uses

Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.

Definition

ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, 1 and D5 receptors respectively).

General Description

(S)-(?)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

Biological Activity

Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively).

Biochem/physiol Actions

(S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9

storage

Room temperature

Levosulpiride Preparation Products And Raw materials

Raw materials

Lithium tert-butoxide Ethanol Aminosulfonate Sulpiride (S)-2-(Aminomethyl)-1-ethylpyrrolidine 2-(Aminomethyl)-1-ethylpyrrolidine L-Proline Lithium Aluminum Hydride Sodium hydroxide L(+)-Tartaric acid Methyl benzoate

Preparation Products

More
Less

Levosulpiride Suppliers

Americas 1 Argentina 1 Belgium 1 Brazil 1 Canada 4 China 212 Europe 3 Germany 7 India 107 Italy 3 Japan 3 Poland 1 South Korea 8 Switzerland 1 The Netherlands 1 United Kingdom 20 United States 50 Global 424
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Alfa Chemistry
Tel
Email
info@alfa-chemistry.com
Country
United States
ProdList
2344
Advantage
58
Aston Chemical
Tel
13000000000
Email
sales@astonchem.com
Country
United States
ProdList
1634
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Abcam
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6000
Advantage
50
MedKoo Biosciences, Inc.
Tel
--
Fax
--
Email
sales@medkoo.com
Country
United States
ProdList
126
Advantage
58
Crescent Chemical Company
Tel
--
Fax
--
Email
fran@creschem.com
Country
United States
ProdList
1441
Advantage
58
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
eNovation Chemicals LLC
Tel
--
Fax
--
Email
ales@eNovationChem.com
Country
United States
ProdList
1673
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
2A Biotech USA
Tel
--
Fax
--
Email
info@2abiotech.com
Country
United States
ProdList
1785
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
Parchem Fine & Specialty Chemicals
Tel
--
Fax
--
Email
info@parchem.com
Country
United States
ProdList
1031
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
SynInnova Laboratories Inc.
Tel
--
Fax
--
Email
sales@syninnova.com
Country
United States
ProdList
491
Advantage
50
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Ontario Chemicals, Inc
Tel
--
Fax
--
Email
info@ontariochem.com
Country
United States
ProdList
723
Advantage
50
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
W & J PharmaChem, Inc.
Tel
--
Fax
--
Email
info@wjpharmachem.com
Country
United States
ProdList
595
Advantage
50
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
More
Less

View Lastest Price from Levosulpiride manufacturers

Hong Kong Excellence Biotechnology Co., Ltd.
Product
Levosulpiride 23672-07-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20tons
Release date
2023-10-12
Sigma Audley
Product
Levosulpiride 23672-07-3
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-03-15
Sigma Audley
Product
Levosulpiride 23672-07-3
Price
US $45.00-35.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-01-16

23672-07-3, LevosulpirideRelated Search:

METSULFURON METHYL Bensulfuron methyl Amisulpride Thiophanate-methyl Methyl acetate Chlorantraniliprole Methyl acrylate Benzamide Kresoxim-methyl Methylparaben Calcium levofolinate Levomilnacipran Levothyroxine sodium L(+)-Tartaric acid Methyl L(-)-Carvone Levodopa L(-)-Carnitine hydrochloride

  • (s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • (s)-(-)-o-anisamid
  • (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
  • China (S)-(-)-Sulpiride
  • Levosulpiride, (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
  • S-(-)-Sulpiride，Levobren，Levopraid
  • (s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide 5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid ( s-(-)-benzamid
  • rv-12309 s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide
  • s-(-)-sulpiride (S)--5-Aminosulfonyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
  • levosupride
  • (S)-(-)-5-(Aminoulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
  • Levopride
  • 5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-Methoxy-benzaMide
  • 5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-benzaMide
  • l-Sulpirid
  • (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide Levosulpiride
  • (S)-(-)-5-(aMinosulfonyl)-N-[(1-ethyl-2-pyrrolinyl)Methyl]
  • Levosulpiride (Irritable Bowel SyndroMe)
  • (S)-(-)-Sulpir
  • (S)-(-)-SULPIRIDE
  • (S)-(-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE
  • 5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid(
  • levopraid
  • rv-12309
  • s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide
  • (-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXY-BENZAMIDE
  • Levosulpride
  • (S)-(-)-Sulpiride, Vetranal
  • S(-)-SULPIRIDE DOPAMINE D1 ANTAGONIS
  • LEVOSULPIRIDE/LEVOSULPRIDE
  • Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (S)-
  • Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy- (9CI)
  • l-Sulpiride
  • (S)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE
  • (-)-N-1-[ETHYLPYRROLIDIN-2-YLMETHYL]-2-METHOXY-5-SULFAMOYLBENZAMIDE
  • LEVOSULPIRIDE
  • (S)-(-)-Sulpiride, 98%, a selective antagonist for D2 dopamine receptor
  • l-Form
  • LEVOSULPIRIDE (RV-12309)
  • Left-handed sulpiride
  • (S)-(-)-Sulpiride&gt
  • Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-
  • Levosulpiride USP/EP/BP
  • L-Sulpiride Impurity
  • LevosulpirideQ: What is Levosulpiride Q: What is the CAS Number of Levosulpiride Q: What is the storage condition of Levosulpiride Q: What are the applications of Levosulpiride
  • LevosulprideQ: What is Levosulpride Q: What is the CAS Number of Levosulpride
  • Lform of Sulpiride
  • Levosulpiride (S)-(-)-Sulpiride
  • LEVOSULPRIDE 60% SR PELLETS
  • Caprylic Acid Impurity 36
  • (S)-Sulpiride, D2-like dopamine antagonist
  • 23672-07-3
  • C15H23N3O4O4
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • SN - SZ
  • Dopamine receptor