ChemicalBook > CAS DataBase List > 5-Chloro-8-hydroxyquinoline

5-Chloro-8-hydroxyquinoline

Product Name
5-Chloro-8-hydroxyquinoline
CAS No.
130-16-5
Chemical Name
5-Chloro-8-hydroxyquinoline
Synonyms
Cloxyquin;Cloxiquin;cloxiquine;5-CHLORO-8-QUINOLINOL;Cloxyqui;Chlorisept;Cloxyquine;Dermofungin;DERMOFONGIN;5-CHLOROOXINE
CBNumber
CB4434834
Molecular Formula
C9H6ClNO
Formula Weight
179.6
MOL File
130-16-5.mol
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5-Chloro-8-hydroxyquinoline Property

Melting point:
122-124 °C(lit.)
Boiling point:
348.7±22.0 °C(Predicted)
Density 
1.2364 (rough estimate)
vapor pressure 
0.003Pa at 25℃
refractive index 
1.5330 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
0.019g/l (experimental)
form 
Powder
pka
3.77±0.10(Predicted)
color 
Light green to gray
Sensitive 
Light Sensitive
Merck 
14,2422
BRN 
5289
InChIKey
RWPWQYXFGFYJBA-UHFFFAOYSA-N
CAS DataBase Reference
130-16-5(CAS DataBase Reference)
NIST Chemistry Reference
8-Quinolinol, 5-chloro-(130-16-5)
EPA Substance Registry System
8-Quinolinol, 5-chloro- (130-16-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
RTECS 
VC4590000
TSCA 
Yes
HS Code 
29334990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C47000
Product name
5-Chloro-8-quinolinol
Purity
95%
Packaging
100g
Price
$68.6
Updated
2024/03/01
TCI Chemical
Product number
C0645
Product name
5-Chloro-8-hydroxyquinoline
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
C0645
Product name
5-Chloro-8-hydroxyquinoline
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$158
Updated
2024/03/01
Alfa Aesar
Product number
B22856
Product name
5-Chloro-8-hydroxyquinoline, 95%
Packaging
50g
Price
$35.65
Updated
2024/03/01
Alfa Aesar
Product number
B22856
Product name
5-Chloro-8-hydroxyquinoline, 95%
Packaging
250g
Price
$88.65
Updated
2024/03/01
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5-Chloro-8-hydroxyquinoline Chemical Properties,Usage,Production

Chemical Properties

light green to grey powder

Uses

antibacterial, antifungal

Uses

Dermofungin, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.

Definition

ChEBI: Cloxiquine is a member of quinolines and an organochlorine compound.

Synthesis Reference(s)

The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x

in vitro

Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis .
Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.|
Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.
Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.

in vivo

Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.
Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.

5-Chloro-8-hydroxyquinoline Preparation Products And Raw materials

Raw materials

8-Hydroxyquinoline

Preparation Products

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5-Chloro-8-hydroxyquinoline Suppliers

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View Lastest Price from 5-Chloro-8-hydroxyquinoline manufacturers

airuikechemical co., ltd.
Product
5-Chloro-8-hydroxyquinoline 130-16-5
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-10
Hebei Weibang Biotechnology Co., Ltd
Product
5-Chloro-8-hydroxyquinoline 130-16-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
5-Chloro-8-hydroxyquinoline 130-16-5
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-01

130-16-5, 5-Chloro-8-hydroxyquinolineRelated Search:

8-Hydroxyquinoline Quinhydrone 5,7-Dichloro-8-hydroxyquinoline 5,7-Dichloro-8-hydroxyquinaldine Cloquintocet-mexyl 7-BROMO-5-CHLORO-8-HYDROXYQUINOLINE 98+%,7-BROMO-5-CHLORO-8-HYDROXYQUINOLINE PEST ANAL,7-BROMO-5-CHLORO-8-HYDROXYQUINOLINE Difluorochloromethane 7-IODO-5-CHLORO-8-HYDROXYQUINOLINE 97%,7-IODO-5-CHLORO-8-HYDROXYQUINOLINE,N-IODO-5-CHLORO-8-HYDROXYQUINOLINE 7-CHLORO-4-HYDROXYQUINOLINE,7-CHLORO-4-HYDROXYQUINOLINE, 98+%,7-CHLORO-4-HYDROXYQUINOLINE 97+% 6-CHLORO-4-HYDROXYQUINOLINE 7-CHLORO-4-HYDROXY QUINOLINE-3-CARBOXYLIC ACID 4-CHLORO-2-HYDROXYQUINOLINE 5,7-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 6-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 5,8-DICHLORO-4-HYDROXYQUINOLINE 8-CHLORO-2-HYDROXYQUINOLINE 7-CHLORO-2-HYDROXYQUINOLINE,7-CHLORO-2-HYDROXYQUINOLINE, 98+% 5-AMINO-3-ISOPROPYL-1,2,4-THIADIAZOLE

  • 5-Chloro-8-quinolinol, >=98%
  • 5-CHLORO-8-HYDROXYQUINOLINE
  • 5-CHLORO-8-QUINOLINOL
  • 5-CHLOROOXINE
  • 5-CHLOROQUINOPHENOL
  • Clioquinol EP Impurity A
  • 5-Chloro-8-oxyquinoline
  • 5-chloro-8-quinolino
  • 5-Chloro-8-quinolol
  • 8-Hydroxy-5-chloroquinoline
  • Chlorisept
  • Chloroxyquinoline
  • Cloxyqui
  • Cloxyquin
  • Dermofungin
  • Monochlorohydroxyquinoline
  • DERMOFONGIN
  • cloxiquine
  • 5-CHLORO-8-HYDROXYQUINOLINE CRYSTALLINE
  • 8-Quinolinol, 5-chloro-
  • Cloxyquine
  • 5-Chlorooxine 5-Chloro-8-quinolinol 5-Chloroquinophenol
  • 5-Chloro-8-hydroxyqu
  • 5-chloro-8hydroxyquninoline
  • 5-Chloro-8-hydroxyquinoline, 95% 100GR
  • 5-CHLORO-8-QUINOLINOL 99+%
  • 5-CHLORO-8-HYDROXYQUINOLINE 95%
  • Cloxiquin
  • 5-Chloro-8-hydroxyquinoline,95%
  • Clioquinol EP IMpurity A (Cloxyquin)
  • Chloro-8-quinoli
  • Clioquinol EP Impurit
  • 5-Chloro-8-hydroxyquinoline &gt
  • 5-Chloro-8-hydroxyquinoline USP/EP/BP
  • Manufacturer Supplying High Quality?5-Chloro-8-Hydroxyquinoline CAS:?130-16-5
  • 5-Chloro-8-hydroxyquinolineQ: What is 5-Chloro-8-hydroxyquinoline Q: What is the CAS Number of 5-Chloro-8-hydroxyquinoline Q: What is the storage condition of 5-Chloro-8-hydroxyquinoline
  • Clioquinol Impurity 1
  • Ergothioneine-d3
  • 5-Chloro-8-quinolinol, 5-Chloro-8-hydroxyquinoline
  • Clioquinol Impurity A
  • 130-16-5
  • C9H6NOCl
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Quinolines
  • Hydroxyquinolines
  • Haloquinolines
  • Quinolines
  • Haloquinolines
  • Hydroxyquinolines
  • pesticide intermediates
  • Quinolines, Quinazolines and derivatives
  • API
  • 130-16-5