Reaction
ChemicalBook > CAS DataBase List > (R)-(+)-1-(4-PYRIDYL)ETHANOL

(R)-(+)-1-(4-PYRIDYL)ETHANOL

Reaction
Product Name
(R)-(+)-1-(4-PYRIDYL)ETHANOL
CAS No.
27854-88-2
Chemical Name
(R)-(+)-1-(4-PYRIDYL)ETHANOL
Synonyms
(1R)-1-(4-Pyridyl)ethanol;(R)-1-(pyridin-4-yl)ethanol;(R)-(+)-1-(4-PYRIDYL)ETHANOL;4-[(R)-1-Hydroxyethyl]pyridine;(R)-1-(pyridin-4-yl)ethan-1-ol;(1R)-1-(pyridin-4-yl)ethan-1-ol;(R)-4-(1-HYDROXYETHYL) PYRIDINE;(R)-α-Methylpyridine-4-methanol;(aR)-a-Methyl-4-PyridineMethanol;(αR)-α-Methylpyridine-4-methanol
CBNumber
CB4444367
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
27854-88-2.mol
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(R)-(+)-1-(4-PYRIDYL)ETHANOL Property

Melting point:
67-69 °C(lit.)
Boiling point:
239.7±15.0 °C(Predicted)
Density 
1.082±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
soluble in Methanol
pka
13.52±0.20(Predicted)
form 
Crystalline Powder or Needles
color 
White
optical activity
[α]20/D +55°, c = 1 in chloroform
BRN 
4306037
InChIKey
HVOAMIOKNARIMR-ZCFIWIBFSA-N
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
3-10
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
448532
Product name
(R)-(+)-α-Methyl-4-pyridinemethanol
Purity
99%
Packaging
1g
Price
$160
Updated
2023/01/07
TCI Chemical
Product number
H1733
Product name
(R)-4-(1-Hydroxyethyl)pyridine
Packaging
1G
Price
$103
Updated
2024/03/01
TCI Chemical
Product number
H1733
Product name
(R)-4-(1-Hydroxyethyl)pyridine
Packaging
5G
Price
$355
Updated
2024/03/01
Strem Chemicals
Product number
07-1160
Product name
(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98%
Packaging
50mg
Price
$70
Updated
2024/03/01
Strem Chemicals
Product number
07-1160
Product name
(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98%
Packaging
100mg
Price
$111
Updated
2024/03/01
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(R)-(+)-1-(4-PYRIDYL)ETHANOL Chemical Properties,Usage,Production

Reaction

  1. Used for the synthesis of chiral 1-(4-pyridinyl)ethylamines
  2. Precursor for intermediates of highly stable chiral (A)6-B Supramolecular Copolymers

Chemical Properties

White needles

Uses

(1R)-1-(4-Pyridyl)ethanol is a building block reagent used in the synthesis of potent GPR119 receptor agonists used in the treatment of diabetes.

Purification Methods

Purify it by recrystallisation from pet ether. The m recorded after sublimation was 59.9-60.2o, and 55o after crystallisation from *C6H6/pet ether or pet ether/*C6H6. The (-)-di-O-benzoyl tartrate salt has m 146-148o (from EtOH). [UV, ORD: Harelli & Samori J Chem Soc Perkin Trans 2 1462 1974.] The racemate recrystallises from Et2O with m 74-76o,b 90-94o/1mm. The picrate has m 125-126o (from *C6H6). [Ferles & Attia Collect Czech Chem Commun 38 611 1973, UV, NMR: Nielson et al. J Org Chem 29 2898 1964, Beilstein 21 III/IV 522, 21/2 V 217.]

(R)-(+)-1-(4-PYRIDYL)ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-1-(4-PYRIDYL)ETHANOL Suppliers

CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6682
Advantage
30
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View Lastest Price from (R)-(+)-1-(4-PYRIDYL)ETHANOL manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(R)-(+)-1-(4-PYRIDYL)ETHANOL 27854-88-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Dideu Industries Group Limited
Product
(R)-(+)-1-(4-PYRIDYL)ETHANOL 27854-88-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-11
Career Henan Chemical Co
Product
(R)-(+)-1-(4-PYRIDYL)ETHANOL 27854-88-2
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-20

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