tert-Butyl 2,6-dichloroisonicotinate
- Product Name
- tert-Butyl 2,6-dichloroisonicotinate
- CAS No.
- 75308-46-2
- Chemical Name
- tert-Butyl 2,6-dichloroisonicotinate
- Synonyms
- TERT-BUTYL 2,6-DICHLOROISONICOTINATE;tert-Butyl 2,6-Dichloroisonicotinate >tert-Butyl 2,6-Dichloroisonicotinate;2,6-Dichloroisonicotinic Acid t-butyl ester;tert-Butyl 2,6-Dichloropyridine-4-carboxylate;tert-Butyl 2,6-dichloro-4-pyridinecarboxylate;2,6-Dichloroisonicotinic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid 1,1-dimethylethyl ester;4-Pyridinecarboxylic acid, 2,6-dichloro-, 1,1-dimethylethyl ester
- CBNumber
- CB4669250
- Molecular Formula
- C10H11Cl2NO2
- Formula Weight
- 248.11
- MOL File
- 75308-46-2.mol
tert-Butyl 2,6-dichloroisonicotinate Property
- Melting point:
- 80.0 to 84.0 °C
- Boiling point:
- 326°C
- Density
- 1.278
- Flash point:
- 151°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- -4.43±0.10(Predicted)
- color
- White to Light yellow to Light orange
- CAS DataBase Reference
- 75308-46-2(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B3595
- Product name
- tert-Butyl 2,6-Dichloroisonicotinate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $157
- Updated
- 2025/07/31
- Product number
- B903155
- Product name
- tert-Butyl 2,6-Dichloroisonicotinate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B903155
- Product name
- tert-Butyl 2,6-Dichloroisonicotinate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB149300
- Product name
- tert-Butyl 2,6-Dichloroisonicotinate
- Packaging
- 250mg
- Price
- $57.5
- Updated
- 2021/12/16
- Product number
- 1699AC
- Product name
- tert-Butyl 2,6-Dichloroisonicotinate
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
tert-Butyl 2,6-dichloroisonicotinate Chemical Properties,Usage,Production
Synthesis
To a solution of 2,6-dichloroisonicotinic acid (2 g, 10.4 mmol) in toluene (50 mL) N, N- dimethylformamide di-fert-butil acetal (15 mL, 62.5 mmol) was added under nitrogen atmosphere and mixture heated at 80°C overnight. Ethyl acetate was added, and the organic layer was washed with water and brine, dried (MgS04), filtered and concentrated to yield tert-Butyl 2,6-dichloroisonicotinate (2.34 g, 87 per cent) as a solid.
References
[1] Patent: WO2008/11499, 2008, A1. Location in patent: Page/Page column 37-38
[2] Organic Process Research and Development, 2009, vol. 13, # 6, p. 1145 - 1155
[3] Patent: WO2010/111058, 2010, A1. Location in patent: Page/Page column 79
tert-Butyl 2,6-dichloroisonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl 2,6-dichloroisonicotinate Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from tert-Butyl 2,6-dichloroisonicotinate manufacturers
- Product
- tert-Butyl 2,6-dichloroisonicotinate 75308-46-2
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08