3-Iodopyridin-2-amine

Product Name: 3-Iodopyridin-2-amine
CAS No.: 104830-06-0
Chemical Name: 3-Iodopyridin-2-amine
Synonyms: 3-iodo-2-aMinopyridine;3-IODOPYRIDIN-2-AMINE;3-Iodopyrid-2-ylaMine;3-IODO-2-PYRIDINAMINE;2-AMINO-3-IODOPYRIDINE;2-Pyridinamine, 3-iodo-;3-IODO-PYRIDIN-2-YLAMINE;2-Amino-3-iodopyridine >2-Amino-3-iodopyridine,98%;2-Amino-3-iodopyridine 97%
CBNumber: CB4704524
Molecular Formula: C5H5IN2
Formula Weight: 220.01
MOL File: 104830-06-0.mol

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3-Iodopyridin-2-amine Property

Melting point:: 87-91 °C
Boiling point:: 289.6±25.0 °C(Predicted)
Density: 2.055±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
pka: 4.50±0.36(Predicted)
form: Powder, Crystalline Powder or Needles
color: White to pale brown
Sensitive: Air & Light Sensitive
InChI: InChI=1S/C5H5IN2/c6-4-2-1-3-8-5(4)7/h1-3H,(H2,7,8)
InChIKey: UUDNBWSHTUFGDQ-UHFFFAOYSA-N
SMILES: C1(N)=NC=CC=C1I
CAS DataBase Reference: 104830-06-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 2
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 704474
Product name: 2-Amino-3-iodopyridine
Purity: 96%
Packaging: 5g
Price: $79.8
Updated: 2023/06/20

TCI Chemical

Product number: A2542
Product name: 2-Amino-3-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: A2542
Product name: 2-Amino-3-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $89
Updated: 2025/07/31

TRC

Product number: I719433
Product name: 3-Iodopyridin-2-amine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA32708
Product name: 2-Amino-3-iodopyridine
Packaging: 1g
Price: $60
Updated: 2021/12/16

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3-Iodopyridin-2-amine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Needles

Uses

2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis[1].

Synthesis

113975-31-8

104830-06-0

General procedure for the synthesis of 2-amino-3-iodopyridine from N-(3-iodopyridin-2-yl)palmitamide: N-(3-iodopyridin-2-yl)neopentanamide (13.80 g, 45.36 mmol) was dissolved in 24 wt% sulfuric acid solution (394 mL), and the reaction mixture was stirred for 60 min under reflux conditions. After completion of the reaction, it was cooled to room temperature and neutralized with 4N sodium hydroxide solution and solid sodium bicarbonate. The aqueous phase was extracted with dichloromethane (3 x 200 mL), the organic phases were combined and dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by rotary evaporator to give 3-iodopyridin-2-amine (9.70 g, 97% yield) as a cream colored solid.

References

[1] Patent: US2009/156593, 2009, A1. Location in patent: Page/Page column 17
[2] Patent: US2006/183758, 2006, A1. Location in patent: Page/Page column 8
[3] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 51
[4] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 53
[5] Patent: US2010/331282, 2010, A1. Location in patent: Page/Page column 10

3-Iodopyridin-2-amine Preparation Products And Raw materials

Raw materials

Ethanol Potassium hydroxide Potassium iodide 2-Chloro-3-pyridinamine Sodium sulfite Potassium carbonate Chloroform Sodium nitrite Hydrochloric acid Ammonia

Preparation Products

2-AMINO-3,5-DIIODOPYRIDINE

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3-Iodopyridin-2-amine Suppliers

Americas 1 China 209 Europe 2 France 1 Germany 6 India 13 Japan 1 Poland 1 United Kingdom 7 United States 30 Global 271

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Synchem OHG

Tel: +49 5662 408730
Fax: +49 5662 4087320
Email: info@synchem.de
Country: Germany
ProdList: 4705
Advantage: 70

Toroma Organics Ltd

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Country: Germany
ProdList: 223
Advantage: 58

PARAGOS

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Email: info@paragos.com
Country: Germany
ProdList: 6371
Advantage: 39

Service Chemical Inc.

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Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

ABCR GmbH & CO. KG

Tel: --
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Email: info@abcr.de
Country: Germany
ProdList: 6831
Advantage: 75

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View Lastest Price from 3-Iodopyridin-2-amine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Iodopyridin-2-amine 104830-06-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

PNP Biotech Co. Ltd

Product: 2-Amino-3-iodopyridine 104830-06-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-04

Dideu Industries Group Limited

Product: 3-Iodopyridin-2-amine 104830-06-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

104830-06-0, 3-Iodopyridin-2-amineRelated Search:

Triethylamine 2-Chloro-3-hydroxypyridine N-Ethylmethylamine 4-Dimethylaminopyridine Triethanolamine Dibenzylamine 3-Hydroxypyridine 2-Aminopyridine 3-Aminopyridine Bis(2-ethylhexyl)amine 2-AMINO-3,5-DIIODOPYRIDINE 3-IODO-2-NITROPYRIDINE 1-(3-IODO-PYRIDIN-2-YL)-PIPERAZINE 5-Bromo-3-iodopyridin-2-amine N-CYCLOPROPYL-3-IODOPYRIDIN-2-AMINE 2-AMINO-3-IODO-5-NITROPYRIDINE 2-Amino-3-iodo-6-methylpyridine 4-(3-IODO-PYRIDIN-2-YL)-MORPHOLINE

3-IODOPYRIDIN-2-AMINE

3-IODO-PYRIDIN-2-YLAMINE

2-Amino-3-iodopyridine 97%

3-IODO-PYRIDIN-2-YLAMINE,98%

3-iodo-2-aMinopyridine

3-Iodopyrid-2-ylaMine

2-Amino-3-iodopyridine,98%

2-AMINO-3-IODOPYRIDINE

2-Amino-3-iodopyridine &gt

2-Pyridinamine, 3-iodo-

3-Iodopyridin-2-amine ISO 9001：2015 REACH

3-IODO-2-PYRIDINAMINE

2-Amino-3-iodopyridine, 95%

104830-06-0

104830-06

104803-06-0

Boronic Acid

Amines

Pyridines

Pyridine

Amines and Anilines

Heterocycles