ChemicalBook > CAS DataBase List > 2-Amino-4-chloro-6-methoxypyrimidine
2-Amino-4-chloro-6-methoxypyrimidine
- Product Name
- 2-Amino-4-chloro-6-methoxypyrimidine
- CAS No.
- 5734-64-5
- Chemical Name
- 2-Amino-4-chloro-6-methoxypyrimidine
- Synonyms
- ACMP;2-Pyrimidinamine, 4-chloro-6-methoxy-;TIMTEC-BB SBB003975;2-amino-4-chloro-6-methoxypyri;2-Amino-4-methoxy-6-chloropyri;4-chloro-6-methoxy-2-pyrimidinamin;2-AMino-4-chloro-6-MethylyriMidine;4-Chloro-6-methoxy-2-pyrimidinamine;2-amino-4-chloro-6-methoxypyrimidne;4-methoxy-6-chloro-2-aminopyrimidine
- CBNumber
- CB4707363
- Molecular Formula
- C5H6ClN3O
- Formula Weight
- 159.57
- MOL File
- 5734-64-5.mol
More
Less
2-Amino-4-chloro-6-methoxypyrimidine Property
- Melting point:
- 168-171 °C (lit.)
- Boiling point:
- 349.4±45.0 °C(Predicted)
- Density
- 1.6625 (rough estimate)
- refractive index
- 1.4510 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 1.96±0.10(Predicted)
- form
- Crystalline Powder
- color
- Light yellow
- CAS DataBase Reference
- 5734-64-5(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Pyrimidinamine, 4-chloro-6-methoxy- (5734-64-5)
More
Less
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 518646
- Product name
- 2-Amino-4-chloro-6-methoxypyrimidine
- Purity
- 95%
- Packaging
- 10g
- Price
- $55.9
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 518646
- Product name
- 2-Amino-4-chloro-6-methoxypyrimidine
- Purity
- 95%
- Packaging
- 50g
- Price
- $164
- Updated
- 2023/06/20
TCI Chemical
- Product number
- A1520
- Product name
- 2-Amino-4-chloro-6-methoxypyrimidine
- Purity
- >95.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $21
- Updated
- 2025/07/31
TCI Chemical
- Product number
- A1520
- Product name
- 2-Amino-4-chloro-6-methoxypyrimidine
- Purity
- >95.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $23
- Updated
- 2025/07/31
Usbiological
- Product number
- 295304
- Product name
- 2-Amino-6-chloro-4-methoxypyrimidine
- Packaging
- 5g
- Price
- $275
- Updated
- 2021/12/16
More
Less
2-Amino-4-chloro-6-methoxypyrimidine Chemical Properties,Usage,Production
Chemical Properties
light yellow crystalline powder
Uses
2-Amino-4-chloro-6-methoxy-pyrimidine is one of the two major metabolites formed in the degradation of chlorimuron-ethyl; a pre- and post-emergence herbicide for the control of important broad-leaved weeds in soybean and maize.
Synthesis
67-56-1
56-05-3
5734-64-5
GENERAL PROCEDURE: Intermediate Id-f was prepared similarly to Intermediate Ia-c. Anhydrous tetrahydrofuran (12 mL) solution of sodium hydride (5.8 mmol) was cooled to 0 °C under nitrogen protection, followed by slow dropwise addition of substitutional alcohol (6.1 mmol). The reaction mixture was kept stirred at 0 °C for 15 min. Then, 2-amino-4,6-dichloropyrimidine (5.8 mmol) was added to the reaction system. The reaction temperature was raised to 62°C and the reaction was continued for 15 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched with 1 M hydrochloric acid solution (1 mL). The reaction mixture was diluted with ethyl acetate (20 mL), washed twice sequentially with saturated sodium bicarbonate solution (20 mL) and brine (20 mL), and the organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography (ethyl acetate/petroleum ether as eluent) to afford the target compound Id-f. 4-Chloro-6-methoxypyrimidin-2-amine (Id) was a white solid with a melting point of 165-167 °C in 84% yield.1H-NMR (CDCl3) δ 6.04 (s, 1H, ArH), 5.35-5.14 (m, 2H , NH2), 3.81 (s, 3H, OCH3).
References
[1] Patent: WO2004/37795, 2004, A1. Location in patent: Page/Page column 8
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[3] Molecules, 2018, vol. 23, # 9,
[4] Nippon Kagaku Zasshi, 1953, vol. 74, p. 624
[5] Chem.Abstr., 1954, p. 13693
2-Amino-4-chloro-6-methoxypyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-Amino-4-chloro-6-methoxypyrimidine Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-60275820 13031183356
- Fax
- 010-60270825
- elainezt@sina.com
- Country
- China
- ProdList
- 1390
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 15527621225
- 1791901229@qq.com
- Country
- China
- ProdList
- 6945
- Advantage
- 52
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11705
- Advantage
- 57
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9546
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 0570-3066667
- Fax
- 0570-3063388
- Country
- China
- ProdList
- 3930
- Advantage
- 58
- Tel
- 021-021-64975436 18917636693
- Fax
- 021-24280809
- 1377976036@qq.com
- Country
- China
- ProdList
- 308
- Advantage
- 55
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 010-51268198
- Fax
- 010-63833209
- leadershipchem@126.com
- Country
- China
- ProdList
- 2546
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- 021-58957966 18930537195
- Fax
- 021-60899437
- wouchina@126.com
- Country
- China
- ProdList
- 3027
- Advantage
- 58
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 021-60899189-8001 18918189673
- Fax
- 021-60899304
- gtchem@126.com
- Country
- China
- ProdList
- 2656
- Advantage
- 58
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 6295
- Advantage
- 60
- Tel
- 400-821-5857 021-64326257
- Fax
- 021-64393586 QQ;2798200800
- credit-chem@foxmail.com
- Country
- China
- ProdList
- 5219
- Advantage
- 58
- Tel
- 027-59262863 13277907145 3091977954
- Fax
- 027-59420980
- Country
- China
- ProdList
- 4942
- Advantage
- 58
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 021-69106960 13701823733
- Fax
- 021-69106780
- 13701823733@163.com
- Country
- China
- ProdList
- 4641
- Advantage
- 60
- Tel
- 010-56218822 13717722232
- Fax
- 010-56218800
- xinsavichem@163.com
- Country
- China
- ProdList
- 3201
- Advantage
- 56
- Tel
- 13718199399
- Fax
- QQ : 206661479
- holiyangchem@163.com
- Country
- China
- ProdList
- 3280
- Advantage
- 56
- Tel
- 021-69005955 13701776567
- Fax
- 021-69005775
- youpengchem@163.com
- Country
- China
- ProdList
- 4161
- Advantage
- 56
- Tel
- 13708085536 13708085536
- Fax
- QQ : 121102042
- hanovichem@163.com
- Country
- China
- ProdList
- 3282
- Advantage
- 56
- Tel
- 021-021-69182866 13701855675
- Fax
- 021-69182022
- tongyuanchem@126.com
- Country
- China
- ProdList
- 4193
- Advantage
- 58
- Tel
- 021-33516722 13701817765
- Fax
- 021-33516776
- kaisaichem@163.com
- Country
- China
- ProdList
- 4610
- Advantage
- 58
- Tel
- 13716033033
- Fax
- 010-56276266
- hanchochem@163.com
- Country
- China
- ProdList
- 2960
- Advantage
- 50
More
Less
View Lastest Price from 2-Amino-4-chloro-6-methoxypyrimidine manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 2-Amino-4-chloro-6-methoxypyrimidine 5734-64-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
Shaanxi Dideu Medichem Co. Ltd
- Product
- 2-Amino-4-chloro-6-methoxypyrimidine 5734-64-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
Career Henan Chemical Co
- Product
- 2-Amino-4-chloro-6-methoxypyrimidine 5734-64-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20
5734-64-5, 2-Amino-4-chloro-6-methoxypyrimidineRelated Search:
ALTRENOGEST
p-Anisaldehyde
4-Methoxybenzylchloride
2-Amino-4-chloropyrimidine
(Trifluoromethoxy)benzene
2-Amino-4,6-dimethoxypyrimidine
3-Aminophenol
6-Aminocaproic acid
2-Aminopyrimidine
Glycine
Anisole
4-Amino-6-methoxypyrimidine
2-Methylsulfonyl-4,6-dimethoxypyrimidine
2-Amino-4-methoxy-6-methyl-1,3,5-triazine
2-Amino-4,6-dimethylpyrimidine
Tris(hydroxymethyl)aminomethane
2-Aminobenzylchloride
Difluorochloromethane