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STREPTAVIDIN

Background
Product Name
STREPTAVIDIN
CAS No.
9013-20-1
Chemical Name
STREPTAVIDIN
Synonyms
STREPTAVIDIN RESIN;STREPTAVIDIN AGAROSE;STREPTAVIDIN;ULTRALINK SA;Polystreptavidin;ALP-Streptavidin;FITC-Streptavidin;STREPTAVIDIN, TYPEII;AGAROSE STREPTAVIDIN;Streptavidin avidinii
CBNumber
CB4710600
Molecular Formula
C14H17BrClNO2S
Formula Weight
378.71228
MOL File
9013-20-1.mol
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STREPTAVIDIN Property

storage temp. 
-20°C
solubility 
H2O: 0.1 mg/mL, clear, colorless
form 
lyophilized powder
color 
White
Water Solubility 
Gives a clear solution at 5mg/ml in 0.1M NaCl. is soluble in water at 1 mg/mL, or in phosphate buffered saline (PBS).
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-21/22
Safety Statements 
24/25-36-26-36/37
WGK Germany 
3
3-10
HS Code 
35040090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S4762
Product name
Streptavidin from Streptomyces avidinii
Purity
essentially salt-free, lyophilized powder, ≥13?units/mg protein
Packaging
0.1mg
Price
$15.32
Updated
2024/03/01
Sigma-Aldrich
Product number
S4762
Product name
Streptavidin from Streptomyces avidinii
Purity
essentially salt-free, lyophilized powder, ≥13?units/mg protein
Packaging
0.5mg
Price
$73.8
Updated
2024/03/01
Sigma-Aldrich
Product number
189730
Product name
Streptavidin
Packaging
1mg
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
189730
Product name
Streptavidin
Packaging
10mg
Price
$686
Updated
2024/03/01
TCI Chemical
Product number
S0951
Product name
Streptavidin from Streptomyces avidinii
Packaging
1vial
Price
$153
Updated
2024/03/01
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STREPTAVIDIN Chemical Properties,Usage,Production

Background

Streptavidin is a biotin-binding protein found in the culture broth of the bacterium Streptomyces avidinii. Streptavidin can bind to four moles of biotin per mole of protein,and it shows extremely high affinity, approximately 10,000-15,000 Da. Streptavidin lacks the carbohydrate side chains present on avidin and has an isoelectric point of 6.5 to avidin's 10 far closer to that at which most useful biological interactions occur. As a result, Streptavidin frequently exhibits much lower non-specific binding than avidin does.

Uses

Streptavidin is used as a tetrameric protein used to visualize biotin conjugated molecules in ELISA. Due to the strong affinity of biotin and biotinylated molecules has made streptavidin one of the most important components in diagnostics and laboratory kits. Streptavidin is widely used in molecular biology through its unique high affinity for the biotin.

Uses

Streptavidin from Streptomyces avidinii has been used-

  • for blocking of the AFM (atomic force microscopy) tip, during the measurement of unbinding forces in the avidin-biotin system
  • for coupling of anti-HA (hemagglutinin) antibodies during cell free synthesis and assembly of proteins on a biochip
  • for the coating of the gelatin flow phantoms to eventually determine the feasibility of IVUS (intravascular ultrasound) transducer for (biotinylated) microbubble-based drug delivery
  • to immobilize proteins and oligonucleotides

Uses

Applications for enzyme-labeled (HRP, AP) streptavidin: Enzyme immunoassays (EIA), including enzyme-linked immunsorbent assays (ELISA) with biotinylated antibodies Cell and tissue staining (for light microscopy) Western blotting (WB) and other membrane-based biotin detection Applications for fluorescent (FITC, TRITC or Texas Red* Fluor-labeled) streptavidin: Immunofluorescent assays (IFA) Tissue staining (for fluorescence microscopy) Blot immunostaining Cell staining (incl. fluorescent activated cell sorting)

General Description

Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. It has four binding sites for biotin like avidin and binds four molecules of biotin. Streptavidin is now considered as a new type of biotin-binding protein.

Biochem/physiol Actions

Streptavidin is a biotin binding protein and has the ability to bind four molecules of biotin. The biotin binding pocket of streptavidin helps to interact with biotin. It can be used to enhance protein binding and multimerization.

STREPTAVIDIN Preparation Products And Raw materials

Raw materials

Preparation Products

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STREPTAVIDIN Suppliers

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View Lastest Price from STREPTAVIDIN manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Streptavidin 9013-20-1
Price
US $0.00/mg
Min. Order
5mg
Purity
≥15.7 units/mg protein
Supply Ability
200g/month
Release date
2021-07-09
Hebei Weibang Biotechnology Co., Ltd
Product
STREPTAVIDIN 9013-20-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Wuhan Monad Medicine Tech Co.,LTD
Product
Streptavidin 9013-20-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99.99%
Supply Ability
20 tons/month
Release date
2021-04-19

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