ChemicalBook > CAS DataBase List > Ethyl 3-phenylpropionate

Ethyl 3-phenylpropionate

Product Name
Ethyl 3-phenylpropionate
CAS No.
2021-28-5
Chemical Name
Ethyl 3-phenylpropionate
Synonyms
Ethyl 3-phenylpropanoate;ETHYL DIHYDROCINNAMATE;ETHYL HYDROCINNAMATE;3- benzenepropanoate;3-Ethyl phenylpropionate;ethylphenylpropionate;ethylphenyl propanoate;FEMA 2455;3-phenylpentanoate;RARECHEM AL BI 0160
CBNumber
CB4744955
Molecular Formula
C11H14O2
Formula Weight
178.23
MOL File
2021-28-5.mol
More
Less

Ethyl 3-phenylpropionate Property

Melting point:
122-124 °C
Boiling point:
247-248 °C(lit.)
Density 
1.01 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.494(lit.)
FEMA 
2455 | ETHYL 3-PHENYLPROPIONATE
Flash point:
226 °F
storage temp. 
2-8°C
solubility 
Chloroform (Soluble), DMSO (Slightly), Methanol
form 
Oil
color 
Colourless
Specific Gravity
1.013
Odor
at 100.00 %. hyacinth rose honey fruity rum
Odor Type
floral
Water Solubility 
<0.1 g/100 mL at 25 ºC
JECFA Number
644
BRN 
1910432
InChIKey
JAGZUIGGHGTFHO-UHFFFAOYSA-N
LogP
2.79
CAS DataBase Reference
2021-28-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzenepropanoic acid, ethyl ester(2021-28-5)
EPA Substance Registry System
Ethyl 3-phenylpropionate (2021-28-5)
More
Less

Safety

Safety Statements 
23-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29163900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
284416
Product name
Ethyl hydrocinnamate
Purity
99%
Packaging
25g
Price
$41.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W245518
Product name
Ethyl 3-Phenylpropionate
Purity
≥98%, FG
Packaging
sample
Price
$59.8
Updated
2023/01/07
TCI Chemical
Product number
P1304
Product name
Ethyl 3-Phenylpropionate
Purity
>98.0%(GC)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
P1304
Product name
Ethyl 3-Phenylpropionate
Purity
>98.0%(GC)
Packaging
250g
Price
$237
Updated
2024/03/01
Alfa Aesar
Product number
A13055
Product name
Ethyl 3-phenylpropionate, 98+%
Packaging
50g
Price
$57.65
Updated
2024/03/01
More
Less

Ethyl 3-phenylpropionate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Chemical Properties

Ethyl 3-phenylpropionate has an ethereal, rum, fruity, floral odor.

Occurrence

Reported found in rum, passion fruit, plum brandy, caja fruit (Spondias lutea L.) and checkur (Alpinia sessilis).

Uses

Ethyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases.

Definition

ChEBI: Ethyl 3-phenylpropanoate is a fatty acid ester.

Preparation

By hydrogenation of the corresponding ethyl cinnamate in the presence of nickel in alcohol solution.

Aroma threshold values

Detection: 17 to 40 ppb

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 3406, 1985 DOI: 10.1021/jo00218a033
Synthetic Communications, 22, p. 2683, 1992 DOI: 10.1080/00397919208021668
Tetrahedron Letters, 42, p. 781, 2001 DOI: 10.1016/S0040-4039(00)02176-6

General Description

Clear colorless liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Ethyl 3-phenylpropionate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

The flash point of Ethyl 3-phenylpropionate has not been determined. but Ethyl 3-phenylpropionate is probably combustible.

Synthesis

Ethyl 3-phenylpropionate is synthesized by Hydrocinnamic acid and Ethanol by normal esterification.

Ethyl 3-phenylpropionate Preparation Products And Raw materials

Raw materials

Ethyl cinnamate

Preparation Products

More
Less

Ethyl 3-phenylpropionate Suppliers

Americas 1 Belgium 1 China 241 Europe 1 France 3 Germany 5 India 7 Japan 2 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 11 United States 43 USA 1 Global 321
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Alfrebro LLC/ Archer Daniels Midland Company
Tel
--
Fax
--
Email
sforbis@alfrebro.com
Country
United States
ProdList
768
Advantage
58
Beijing Lys Chemicals Co, LTD.
Tel
--
Fax
--
Email
jiayanyong@lyschem.com
Country
United States
ProdList
710
Advantage
58
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
WholeChem, LLC
Tel
--
Fax
--
Email
info@wholechem.com
Country
United States
ProdList
814
Advantage
58
Moellhausen S.P.A.
Tel
--
Fax
--
Country
United States
ProdList
1676
Advantage
58
Tadimety Aromatics Private Limited
Tel
--
Fax
--
Email
correspondence@tadimety.in
Country
United States
ProdList
106
Advantage
58
Pyrazine Specialties, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1265
Advantage
30
Lluch Essence S.L.
Tel
--
Fax
--
Email
web@lluche.com
Country
United States
ProdList
2352
Advantage
58
Augustus Oils Ltd
Tel
--
Fax
--
Email
essentials@augustus-oils.ltd.uk
Country
United States
ProdList
1404
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Lianyungang Ziyan Chemical Co., Ltd.
Tel
--
Fax
--
Email
ziyanchem@gmail.com
Country
United States
ProdList
360
Advantage
0
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Anthem Pharmaceutical Research LLC
Tel
--
Fax
--
Email
sales@anthempharma.com
Country
United States
ProdList
3040
Advantage
30
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Scandinavian Formulas, Inc.
Tel
--
Fax
--
Email
info@scandinavianformulas.com
Country
United States
ProdList
1447
Advantage
55
Davos Chemical Corporation
Tel
--
Fax
--
Email
info@davos.com
Country
United States
ProdList
1640
Advantage
65
Penta Manufacturing Company
Tel
--
Fax
--
Email
sales@pentamfg.com
Country
United States
ProdList
5076
Advantage
65
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
More
Less

View Lastest Price from Ethyl 3-phenylpropionate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-23
JINING XINHE CHEMICAL CO., LTD
Product
Ethyl 3-phenylpropionate 2021-28-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
10ton
Release date
2024-07-18

2021-28-5, Ethyl 3-phenylpropionateRelated Search:

Tris(trimethylsilyl)phosphate Ethyl pyruvate Ethylparaben Ethyl phenylacetate Ethyl cyanoacetate Methyl acrylate Ethyl 2-chloropropionate Ethyl 3-ethoxypropionate Ethyl oleate Ethyl acetate Ethyl acrylate Diethyl phthalate Ethyl formate Ethyl 3-bromopropionate Ethyl levulinate ISOXADIFEN-ETHYL Benzocaine Ethyl 2-bromopropionate

  • ETHYL HYDROCINNAMATE
  • ETHYL B-PHENYLPROPIONATE
  • ETHYL DIHYDROCINNAMATE
  • ETHYL 3-PHENYLPROPIONATE
  • HYDROCINNAMIC ACID ETHYL ESTER
  • FEMA 2455
  • 3- phenylethyl propionate
  • Ethyl hydrocinnaMate 99%
  • 3- benzenepropanoate
  • 3-PHENYLPROPANOIC AID ETHYL ESTER
  • 3-PHENYLPROPIONIC ACID ETHYL ESTER
  • 3-PHENYLPROPANOIC ACID ETHYL ESTER
  • RARECHEM AL BI 0160
  • Benzenepropanoicacid,ethylester
  • Ethyl 3-phenylpropanoate
  • ethyl 3-phenylproprionate
  • ethylphenyl propanoate
  • ethylphenylpropionate
  • Benyl propionic ethyl ester
  • ETHYL 3-PHENYLPROPIONATE 98+%
  • ethyldihydrocinnamate,ethyl3-phenylpropanoate
  • 3-phenylpropionic acid ethyl easter
  • 3-PHENYLPROPIONICACIDETHYLESTER(HYDROCINNAMICACIDETHYLESTER)
  • ETHYL-3-PHENYL PROPIONATE, NATURAL
  • Ethyl hydrocinnamate~3-Phenylpropionic acid ethyl ester
  • Ethyl benzenepropanoate
  • Benzenepropionic acid ethyl ester
  • HYDROCINNAMIC ACID ETHYL ESTER(RG)
  • 3-Ethyl phenylopropionate
  • Ethyl 3-phenylpropio
  • 3-Ethyl phenylpropionate
  • Ethyl 3-Phenylpropion
  • 3-ethylphenyl propanoate
  • 3-phenylpentanoate
  • Ethyl3-Phenylpropionate&gt
  • Ethyl 3-phenylpropionate USP/EP/BP
  • TIANFU-CHEM 3-phenylpropionic acid ethyl easter Cas NO.: 2021-28-5
  • 2021-28-5
  • C6H5CH22COOC2H5
  • C6H5CH2CH2COOC2H5
  • C6H5CH2CH2CO2CH2CH3
  • ESTER
  • Organic Building Blocks
  • Esters
  • Building Blocks
  • C10 to C11
  • Carbonyl Compounds
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • Organic acids
  • Pharmaceutical Intermediates
  • 2021-28-5
  • 11