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Ozagrel hydrochloride

Product Name
Ozagrel hydrochloride
CAS No.
78712-43-3
Chemical Name
Ozagrel hydrochloride
Synonyms
Vega;Ozag;Domenan;OKY-046 HCl;(e)-ohydrat;OZAGREL HCL;OzagrelHcl99%;oky046hydrochloride;Ozagrel Impurity 44;oky-046hydrochloride
CBNumber
CB4765488
Molecular Formula
C13H13ClN2O2
Formula Weight
264.71
MOL File
78712-43-3.mol
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Ozagrel hydrochloride Property

Melting point:
214-217°
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
H2O: soluble
form 
solid
color 
white to off-white
Merck 
14,6980
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference
78712-43-3(CAS DataBase Reference)
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Safety

RIDADR 
3077
WGK Germany 
2
RTECS 
UD3380000
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O1385
Product name
Ozagrel hydrochloride hydrate
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
O1385
Product name
Ozagrel hydrochloride hydrate
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$354
Updated
2022/05/15
TCI Chemical
Product number
O0419
Product name
Ozagrel Hydrochloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
O0419
Product name
Ozagrel Hydrochloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$124
Updated
2024/03/01
Tocris
Product number
1510
Product name
Ozagrelhydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$437
Updated
2021/12/16
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Ozagrel hydrochloride Chemical Properties,Usage,Production

Description

Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.

Uses

Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.

Uses

Antithrombotic;Thromboxane synthase inhibitor

Definition

ChEBI: Ozagrel hydrochloride is an organic molecular entity.

References

1) Hiraku?et al. (1986),?Pharmacological studies on the TXA2?synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046); Jpn. J. Pharmacol.,?41?393 2) Naito?et al. (1983), Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets; Eur. J. Pharmacol.,?91?41 3) Edmonds and Leffer (1984),?Protective actions of a new thromboxane synthetase inhibitor in arachidonate induced sudden death; Life Sci.,?35?1763 4) Tomishima?et al. (2013),?Ozagrel hydrochloride, a selective thromboxane A2?synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice; BMC Gastroenterol.,?30?13

Ozagrel hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ozagrel hydrochloride Suppliers

Americas 1 China 155 Europe 3 Germany 1 India 5 Italy 1 Japan 2 Poland 1 Switzerland 2 United Kingdom 6 United States 28 USA 1 Global 206
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View Lastest Price from Ozagrel hydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Ozagrel hydrochloride 78712-43-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Ozagrel hydrochloride 78712-43-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-19

78712-43-3, Ozagrel hydrochlorideRelated Search:

Ozagrel Folic acid Butyl acrylate Poly(acrylic acid) Ethyl 2-(Chlorosulfonyl)acetate 6-Benzylaminopurine 1-AdaMantanethylaMine PHENYL VALERATE Ethyl acrylate Methacrylic acid Methyl methacrylate Methyl acrylate Phenylhydrazine Topotecan hydrochloride Acrylic acid Ozagrel sodium Glycine Methyl 3-M-tolylacrylate

  • OKY-046, (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrate hydrochloride
  • Ozagrel hydrate hydrochloride
  • Domenan
  • OKY-046 HCl
  • Vega
  • Ozagrel hydrochloride hydrate,(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate, OKY-046
  • (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid,hydrochloride (1:1)
  • (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate
  • Hydrochloride Ozagrel
  • (E)-3-(4-((1H-Imidazol-1-yl)methyl)phenyl)acrylic acid hydrochloride
  • Ozagrel hydrochloride hydrate, 99%, a selective thromboxane A(2) synthetase inhibitor
  • (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride
  • Ozag
  • (e)-3-(4-(1h-imidazol-1-ylmethyl)phenyl)-2-propenoicacidhydrochloridehydra
  • (e)-ohydrat
  • 2-propenoicacid,3-(4-(1h-imidazol-1-ylmethyl)phenyl)-,monohydrochloride,mon
  • oky046hydrochloride
  • oky-046hydrochloride
  • OZAGREL HYDROCHLORIDE HYDRATE
  • OzagrelHcl99%
  • OzagrelHclC13H12N2O2.Hcl
  • (e)-3-[4-(imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride
  • (e)-3-(4-(1h-imidazol-1-ylmethyl)phenyl)-2-propenoic acid hydrochloride
  • OZAGREL HCL
  • OZAGREL HYDROCHLORIDE
  • (2E)-3-[4-(1H-IMIDAZOL-1-YLMETHYL)PHENYL]-2-PROPENOIC ACID HYDROCHLORIDE
  • OzagrelHydrochlorideHydrate&gt
  • Ozagrel Impurity 44
  • (E)-Ozagrel hydrochloride
  • trans-4-[(1-Imidazolyl)methyl]cinnamic Acid Hydrochloride
  • Ozagrel hydrochloride USP/EP/BP
  • Ozagrel HCl (OKY046 HCl
  • 78712-43-3
  • C13H12N2O2ClH
  • C13H12N2O2HCl
  • C13H12N2O2HClxH2O
  • C13H12N2O2ClHH2O
  • R to Z
  • Thromboxane A2 synthase
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Biochemicals and Reagents
  • BioChemical
  • Enzymes, Inhibitors, and Substrates
  • Inhibitors
  • Piperidones ,Piperidines ,Homopiperidines
  • Cardiovascular