Ozagrel hydrochloride
- Product Name
- Ozagrel hydrochloride
- CAS No.
- 78712-43-3
- Chemical Name
- Ozagrel hydrochloride
- Synonyms
- Vega;Ozag;Domenan;OKY-046 HCl;(e)-ohydrat;OZAGREL HCL;OzagrelHcl99%;oky046hydrochloride;Ozagrel Impurity 44;oky-046hydrochloride
- CBNumber
- CB4765488
- Molecular Formula
- C13H13ClN2O2
- Formula Weight
- 264.71
- MOL File
- 78712-43-3.mol
Ozagrel hydrochloride Property
- Melting point:
- 214-217°
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- H2O: soluble
- form
- solid
- color
- white to off-white
- Merck
- 14,6980
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
- CAS DataBase Reference
- 78712-43-3(CAS DataBase Reference)
Safety
- RIDADR
- 3077
- WGK Germany
- 2
- RTECS
- UD3380000
- HS Code
- 29332900
N-Bromosuccinimide Price
- Product number
- O1385
- Product name
- Ozagrel hydrochloride hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $132
- Updated
- 2024/03/01
- Product number
- O1385
- Product name
- Ozagrel hydrochloride hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $354
- Updated
- 2022/05/15
- Product number
- O0419
- Product name
- Ozagrel Hydrochloride Hydrate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $42
- Updated
- 2024/03/01
- Product number
- O0419
- Product name
- Ozagrel Hydrochloride Hydrate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $124
- Updated
- 2024/03/01
- Product number
- 1510
- Product name
- Ozagrelhydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $437
- Updated
- 2021/12/16
Ozagrel hydrochloride Chemical Properties,Usage,Production
Description
Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.
Uses
Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.
Uses
Antithrombotic;Thromboxane synthase inhibitor
Definition
ChEBI: Ozagrel hydrochloride is an organic molecular entity.
References
1) Hiraku?et al. (1986),?Pharmacological studies on the TXA2?synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046); Jpn. J. Pharmacol.,?41?393 2) Naito?et al. (1983), Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets; Eur. J. Pharmacol.,?91?41 3) Edmonds and Leffer (1984),?Protective actions of a new thromboxane synthetase inhibitor in arachidonate induced sudden death; Life Sci.,?35?1763 4) Tomishima?et al. (2013),?Ozagrel hydrochloride, a selective thromboxane A2?synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice; BMC Gastroenterol.,?30?13
Ozagrel hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Ozagrel hydrochloride Suppliers
View Lastest Price from Ozagrel hydrochloride manufacturers
- Product
- Ozagrel hydrochloride 78712-43-3
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 9000kg/per week
- Release date
- 2021-09-08
- Product
- Ozagrel hydrochloride 78712-43-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- Ozagrel hydrochloride 78712-43-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-19