5-METHYLPYRIMIDIN-4-OL

Product Name: 5-METHYLPYRIMIDIN-4-OL
CAS No.: 17758-52-0
Chemical Name: 5-METHYLPYRIMIDIN-4-OL
Synonyms: 5-methyl-4-pyrimidino;5-Methyl-4-pyrimidinol;5-METHYLPYRIMIDIN-4-OL;5-Methyl-3H-pyrimidin-4-one;5-methylpyrimidin-4(3H)-one;5-methyl-1H-pyrimidin-6-one;4-Hydroxy-5-methylpyrimidine;4(3H)-Pyrimidinone,5-methyl-;5-Methyl-4-hydroxypyrimidine;5-Methylpyrimidin-4-Ol(WX649072)
CBNumber: CB4766980
Molecular Formula: C5H6N2O
Formula Weight: 110.11
MOL File: 17758-52-0.mol

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5-METHYLPYRIMIDIN-4-OL Property

Melting point:: 153-154 °C
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 9.18±0.40(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C5H6N2O/c1-4-2-6-3-7-5(4)8/h2-3H,1H3,(H,6,7,8)
InChIKey: SHLJOANTPJWIHS-UHFFFAOYSA-N
SMILES: C1=NC=C(C)C(=O)N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: H939883
Product name: 4-Hydroxy-5-methylpyrimidine
Packaging: 500mg
Price: $155
Updated: 2021/12/16

AK Scientific

Product number: Z4298
Product name: 4-Hydroxy-5-methylpyrimidine
Packaging: 1g
Price: $131
Updated: 2021/12/16

BroadPharm

Product number: BP-11669
Product name: 5-methylpyrimidin-4-ol
Packaging: 500mg
Price: $230
Updated: 2021/12/16

BroadPharm

Product number: BP-11669
Product name: 5-methylpyrimidin-4-ol
Packaging: 1g
Price: $345
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 38027
Product name: 4-Hydroxy-5-methylpyrimidine
Purity: 95+%
Packaging: 250mg
Price: $432
Updated: 2021/12/16

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5-METHYLPYRIMIDIN-4-OL Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 296, 1984 DOI: 10.1021/jo00176a015

Synthesis

636-26-0

17758-52-0

General procedure for the synthesis of 5-methylpyrimidin-4-ol from 4-hydroxy-2-mercapto-5-methylpyrimidine: 4-hydroxy-2-mercapto-5-methylpyrimidine (1.0 g, 7.0 mmol) was suspended in water (50 mL) and ammonia (3 mL) followed by addition of nickel ruanne suspension in water (20 mL). The reaction mixture was heated to reflux for 16 h. Upon completion of the reaction, the filtrate was thermally filtered through diatomaceous earth (10 g) and the filtrate was washed with water (3 x 25 mL). The filtrate was evaporated and concentrated and the resulting solid was azeotropically dried with toluene (2 x 50 mL) to give the final white solid product 5-methylpyrimidin-4-ol (0.75 g, 97% yield).

References

[1] Patent: WO2010/41054, 2010, A1. Location in patent: Page/Page column 40-41

5-METHYLPYRIMIDIN-4-OL Preparation Products And Raw materials

Raw materials

ZINC Ethyl 2-bromopropionate Ethanol Acetone Sodium sulfate Triethyl orthoformate Toluene Sodium Diethyl ether RANEY NICKEL Iodine Hydrochloric acid Sodium bicarbonate Acetic acid Methanol Activated carbon Thiourea Ammonia

Preparation Products

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5-METHYLPYRIMIDIN-4-OL Suppliers

China 63 Europe 1 Germany 2 India 1 The Netherlands 1 United Kingdom 1 United States 14 Global 83

Shanghai Jiezhen Pharmaceutical Technology Co., Ltd.

Tel: 15995055116
Fax: 815229059
Email: 815229059@qq.com
Country: China
ProdList: 142
Advantage: 58

Shaanxi Didu New Material Co., Ltd

Tel: 029-81145920 17391631969
Email: 1046@dideu.com
Country: China
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Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
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Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
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Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
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Shanghai Synthfine Chemical Co.,Ltd

Tel: 15921303235
Fax: QQ489466966
Email: sales@synthfine.com
Country: China
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Advantage: 58

NovoChemy Ltd.

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Country: Germany
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Shanghai Jian Chao Chemical Technology Co., Ltd.

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Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
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Synchem OHG

Tel: +49 5662 408730
Fax: +49 5662 4087320
Email: info@synchem.de
Country: Germany
ProdList: 4705
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View Lastest Price from 5-METHYLPYRIMIDIN-4-OL manufacturers

Dideu Industries Group Limited

Product: 5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-METHYLPYRIMIDIN-4-OL 17758-52-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

17758-52-0, 5-METHYLPYRIMIDIN-4-OLRelated Search:

2-AMINO-4,6-DIHYDROXY-5-METHYLPYRIMIDINE BUPIRIMATE 5-CARBETHOXY-2-THIOURACIL Thymine 2,4-Dihydroxypyrimidine-5-carboxylic acid 2-AMINO-5,6-DIMETHYL-4-HYDROXYPYRIMIDINE 5-Hydroxymethyluracil Pirimicarb 2-AMINO-5-CARBOETHOXY-4-HYDROXYPYRIMIDINE ETHIRIMOL 1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER 2-methylpyrimidin-5-ol,2-METHYLPYRIMIDIN-5-OL,PURITY:95% MIN(HPLC) 6-(CHLOROMETHYL)-2-[(4-METHOXYPHENOXY)METHYL]PYRIMIDIN-4-OL 2-AMINO-6-METHYLPYRIMIDIN-4-OL 6-ETHYL-2-METHYLPYRIMIDIN-4-OL 4-METHYLPYRIMIDIN-2-OL HYDROCHLORIDE 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL 4-HYDROXY-2-METHYLPYRIMIDINE

5-METHYLPYRIMIDIN-4-OL

5-methyl-4-pyrimidino

4-Hydroxy-5-methylpyrimidine

4(1H)-Pyrimidinone, 5-methyl- (9CI)

5-Methyl-4-hydroxypyrimidine

5-Methyl-3H-pyrimidin-4-one

4(3H)-Pyrimidinone,5-methyl-

5-methylpyrimidin-4(3H)-one

5-Methyl-4-pyrimidinol

5-methyl-1H-pyrimidin-6-one

5-Methylpyrimidin-4-Ol(WX649072)

5-METHYLPYRIMIDIN-4-OL ISO 9001：2015 REACH

17758-52-0

PYRIMIDINE