Tilavonemab

Product Name: Tilavonemab
CAS No.: 2096513-89-0
Chemical Name: Tilavonemab
Synonyms: Tilavonemab;Tilavonemab (anti-Tau);Research Grade Tilavonemab;Research Grade Tilavonemab(DHC82403)
CBNumber: CB48080961
Formula Weight: 0
MOL File: Mol file

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Tilavonemab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Tilavonemab Chemical Properties,Usage,Production

Uses

Tilavonemab (ABBV-8E12) is a humanized anti-tau antibody that targets the extracellular form of pathological tau protein aggregates by binding to the N-terminal 25-30 amino acid residues of tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates, reduces the loss of brain volume, slows the progression of tau pathology, and improves cognitive abilities in transgenic mice expressing mutant human tau. Tilavonemab is used in Alzheimer's disease research[1][2][3].

References

[1] Vaswani P A, et al. Immunotherapy in progressive supranuclear palsy. Curr Opin Neurol. 2020 Aug;33(4):527-533. DOI:10.1097/WCO.0000000000000836
[2] Lopez-Cuina M, et al. Targeting alpha-synuclein or tau for treating neurodegenerative movement disorders[J]. Revue Neurologique, 2022, 178(5): 460-471. DOI:10.1016/j.neurol.2022.03.010
[3] Nea?u M, et al. Monoclonal antibody therapy in Alzheimer’s disease[J]. Pharmaceutics, 2023, 16(1): 60. DOI:10.3390/pharmaceutics16010060

Tilavonemab Preparation Products And Raw materials

Raw materials

Preparation Products

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Tilavonemab Suppliers

China 16 Global 16

Shanghai YuanYe Biotechnology Co., Ltd.

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Biolab Reagents

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2096513-89-0, TilavonemabRelated Search:

guselkumab Rilotumumab Bimagrumab Vatelizumab Atibuclimab Serclutamab citatuzumab Glembatumumab Uliledlimab Domagrozumab

Tilavonemab

Research Grade Tilavonemab(DHC82403)

Research Grade Tilavonemab

Tilavonemab (anti-Tau)

2096513-89-0