ChemicalBook > CAS DataBase List > 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE

2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE

Product Name
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
CAS No.
13096-62-3
Chemical Name
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
Synonyms
2,3,4,6-tetra-O-benzyl-D-glucopyranolactone;5-lactone;Tetra-O-benzyl-δ-D-Gluconolactone;2,3,4,6-Tetra-O-benzyl-D-glucono-1;Tetra-O -benzyl-delta-D-Gluconolactone;2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE;2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lacton;2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lactone;2,3,4,6-Tetrakis-O-benzyl-D-glucono-1,5-lactone;2,3,4,6-Tetra-O-benzyl-D-gluconic acid-δ-lactone
CBNumber
CB4849469
Molecular Formula
C34H34O6
Formula Weight
538.63
MOL File
13096-62-3.mol
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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Property

Boiling point:
677.7±55.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
InChIKey
BUBVLQDEIIUIQG-ORMLBLSRNA-N
SMILES
[C@H]1(OCC2=CC=CC=C2)C(=O)O[C@H](COCC2C=CC=CC=2)[C@@H](OCC2=CC=CC=C2)[C@@H]1OCC1=CC=CC=C1 |&1:0,12,22,31,r|
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3793
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1G
Price
$125
Updated
2025/07/31
TRC
Product number
T289210
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
294761
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
1g
Price
$460
Updated
2021/12/16
TRC
Product number
T289210
Product name
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Packaging
10mg
Price
$1175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0092465
Product name
2,3,4,6-TETRAKIS-O-(PHENYLMETHYL)-D-GLUCONIC ACID LACTONE
Purity
95.00%
Packaging
5G
Price
$1848
Updated
2021/12/16
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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Chemical Properties,Usage,Production

Uses

2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone is used as a reactant to synthesize various glucoside containing compounds as selective SGLT2 inhibitors for the treatment of type 2 diabetes mellitus.

Synthesis

6564-72-3

13096-62-3

Example XXI Synthesis of 2,3,4,6-tetra-O-benzyl-D-glucopyranoside: 4 g of freshly activated 4? molecular sieves and 3.3 g of N-methylmorpholine-N-oxide were added to a 140 mL solution of dichloromethane containing 10.0 g of 2,3,4,6-tetra-O-benzyl-α-D-glucopyranose. After stirring the reaction mixture for 20 minutes at room temperature, 0.3 g of tetrapropylammonium perruthenate was added. Stirring was continued at room temperature for 2 h. Upon completion of the reaction, the reaction solution was diluted with dichloromethane and filtered through a diatomaceous earth pad. The filtrate was washed sequentially with aqueous sodium thiosulfate and deionized water and dried over anhydrous sodium sulfate. After concentration under reduced pressure to remove the solvent, the residue was purified by silica gel column chromatography (eluent: cyclohexane/ethyl acetate, 4:1, v/v). The product was obtained as 8.2 g in 82% yield. Mass spectrum (ESI+): m/z = 539 [M + H]+.

References

[1] Patent: WO2005/92877, 2005, A1. Location in patent: Page/Page column 63
[2] Patent: US2006/189548, 2006, A1. Location in patent: Page/Page column 26-27
[3] Patent: US2006/234953, 2006, A1. Location in patent: Page/Page column 14
[4] Patent: US2007/4648, 2007, A1. Location in patent: Page/Page column 14
[5] Patent: US2007/27092, 2007, A1. Location in patent: Page/Page column 26

2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE Suppliers

China 158 Germany 2 India 3 Japan 1 United Kingdom 3 United States 13 Global 180
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE 13096-62-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
2000
Release date
2025-06-05
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone 13096-62-3
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-14
Jinan Shengqi pharmaceutical Co,Ltd
Product
2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE 13096-62-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10MT
Release date
2019-03-21

13096-62-3, 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONERelated Search:

Halofuginone Lactate POLYCAPROLACTONE TRIOL AVERAGE MN CA. Polycaprolactone ALPHA,ALPHA-DIPHENYL-GAMMA-BUTYROLACTONE ROSUVASTATIN LACTONE SEDANOLIDE (-)-Corey Lactone Benzoate (S)-3-Boc-Amino-gamma-butyrolactone L-Homoserine lactone hydrochloride Canrenone Betaine 1,3-Propane sultone Dihydroactinidiolide 2-Acetylbutyrolactone 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one D-(-)-PANTOLACTONE D-(+)-GLUCONO-1,5-LACTONE gamma-Decalactone

  • 2,3,4,6-TETRAKIS-O-(PHENYLMETHYL)-D-GLUCONIC ACID LACTONE
  • 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
  • 5-lactone
  • D-Gluconic acid,2,3,4,6-tetrakis-O-(phenylMethyl)-, d-lactone
  • D-Gluconic acid, 2,3,4,6-tetrakis-O-(phenylMethyl)-, δ-lactone
  • 2,3,4,6-Tetrakis-O-(phenylmethyl)-D-Gluconic Acid, D-Lactone
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-1
  • 2,3,4,6-tetra-O-benzyl-D-glucopyranolactone
  • (3R,4S,5R,6R)-3,4,5-Tris(benzyloxy)-6-(benzyloxymethyl)tetrahydropyran-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-gluconic acid-δ-lactone
  • (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]oxan-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lacton
  • Tetra-O -benzyl-delta-D-Gluconolactone
  • 2,3,4,6-Tetrakis-o-(phenylmethyl)-D-gluconic acid delta-lactone
  • (3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-one
  • 2,3,4,6-Tetra-O-benzyl-D-glucono-delta-lactone
  • TIANFUCHEM--13096-62-3--High purity 6-Methylpyridine-3-carboxylic acid factory price
  • 2,3,4,6-Tetrakis-O-benzyl-D-glucono-1,5-lactone
  • Tetra-O-benzyl-δ-D-Gluconolactone
  • 2,3,4,6-tetra-O-Benzyl-D-glucono-1,5-lactone 95%
  • 13096-62-3
  • C34H34O6
  • Pharmaceutical Intermediates