Thiophene-2-ethylamine
- Product Name
- Thiophene-2-ethylamine
- CAS No.
- 30433-91-1
- Chemical Name
- Thiophene-2-ethylamine
- Synonyms
- 2-(thiophen-2-yl)ethan-1-aMine;2-THIOPHENEETHYLAMINE;2-(2-AMINOETHYL)THIOPHENE;2-Thien-2-yL;ThiopheneEthaMine;RARECHEM AL BW 0099;2-Thiopheneethamine;2-Thiopheneethylamin;2-ThiophenethylaMine;THIOPHENE ETHYLAMINE
- CBNumber
- CB4853460
- Molecular Formula
- C6H9NS
- Formula Weight
- 127.21
- MOL File
- 30433-91-1.mol
Thiophene-2-ethylamine Property
- Melting point:
- 202 °C
- Boiling point:
- 200-201 °C/750 mmHg (lit.)
- Density
- 1.087 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.551(lit.)
- Flash point:
- 190 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 9.47±0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.087
- color
- Colorless to yellow
- Sensitive
- Air Sensitive
- BRN
- 106962
- InChIKey
- HVLUYXIJZLDNIS-UHFFFAOYSA-N
- CAS DataBase Reference
- 30433-91-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-37/39
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 423270
- Product name
- 2-Thiopheneethylamine
- Purity
- 96%
- Packaging
- 1g
- Price
- $18
- Updated
- 2024/03/01
- Product number
- 423270
- Product name
- 2-Thiopheneethylamine
- Purity
- 96%
- Packaging
- 5g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- A1637
- Product name
- 2-(2-Aminoethyl)thiophene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $58
- Updated
- 2024/03/01
- Product number
- A1637
- Product name
- 2-(2-Aminoethyl)thiophene
- Purity
- >98.0%(GC)
- Packaging
- 250g
- Price
- $365
- Updated
- 2024/03/01
- Product number
- A10920
- Product name
- 2-Thiopheneethylamine, 98%
- Packaging
- 1g
- Price
- $35.65
- Updated
- 2024/03/01
Thiophene-2-ethylamine Chemical Properties,Usage,Production
Chemical Properties
A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure.
Uses
[2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90.
Uses
2-Thiopheneethylamine (2-thiophene ethyl amine, 2-(thien-2-yl)ethylamine) is suitable to functionalize multiwall carbon nanotubes (MWCNT).
It may be used as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea.
General Description
2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated.
Synthesis
N,N-Dimethylformamide (DMF) reacts with thiophene to obtain 2-thiophenecarbaldehyde, then reacts with isopropyl chloroacetate to obtain 2-thiopheneacetaldehyde, and then reacts with hydroxylamine hydrochloride to obtain 2-thiopheneacetaldehyde oxime, and finally reduced to give 2-thiopheneethylamine.
References
[1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:10.1007/s00044-012-0438-7.
Thiophene-2-ethylamine Preparation Products And Raw materials
Raw materials
Preparation Products
Thiophene-2-ethylamine Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- --
- Fax
- --
- labchem-tec@wako-chem.co.jp
- Country
- Japan
- ProdList
- 6819
- Advantage
- 80
View Lastest Price from Thiophene-2-ethylamine manufacturers
- Product
- 2-Thiopheneethylamine 30433-91-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2023-09-18
- Product
- Thiophene-2-ethylamine 30433-91-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-13
- Product
- Thiophene-2-ethylamine 30433-91-1
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10MT
- Release date
- 2018-12-21