ChemicalBook > CAS DataBase List > 2-Thiophenemethylamine

2-Thiophenemethylamine

Product Name
2-Thiophenemethylamine
CAS No.
27757-85-3
Chemical Name
2-Thiophenemethylamine
Synonyms
2-THIOPHENEMETHANAMINE;2-Thienylmethanamine;2-THENYLAMINE;AKOS BBS-00003607;2-ThiophenemethyL;thienylmethylamine;TIMTEC-BB SBB004315;RARECHEM AL BW 0257;2-Thiophenemethylami;2-THIENYLMETHYLAMINE
CBNumber
CB5329687
Molecular Formula
C5H7NS
Formula Weight
113.18
MOL File
27757-85-3.mol
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2-Thiophenemethylamine Property

Boiling point:
95-99 °C/28 mmHg (lit.)
Density 
1.103 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5670(lit.)
Flash point:
165 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Easily soluble in ethanol and Chloroform.
pka
8.95±0.29(Predicted)
form 
liquid
color 
Clear colorless to yellow
Sensitive 
Air Sensitive
BRN 
106296
InChI
1S/C5H7NS/c6-4-5-2-1-3-7-5/h1-3H,4,6H2
InChIKey
FKKJJPMGAWGYPN-UHFFFAOYSA-N
SMILES
NCc1cccs1
CAS DataBase Reference
27757-85-3(CAS DataBase Reference)
NIST Chemistry Reference
2-Thiophenemethanamine(27757-85-3)
EPA Substance Registry System
2-Thiophenemethylamine (27757-85-3)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45-25
RIDADR 
UN 3267 8/PG 2
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
III
HS Code 
29349990
Storage Class
8A - Combustible corrosive hazardous materials
Hazard Classifications
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
220884
Product name
2-Thiophenemethylamine
Purity
96%
Packaging
5g
Price
$105
Updated
2025/07/31
TCI Chemical
Product number
A2419
Product name
2-(Aminomethyl)thiophene
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$69
Updated
2025/07/31
TCI Chemical
Product number
A2419
Product name
2-(Aminomethyl)thiophene
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$274
Updated
2025/07/31
TRC
Product number
T430123
Product name
2-Thiophenemethylamine
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
7H30-1-X3
Product name
2-(Aminomethyl)thiophene
Packaging
1g
Price
$16
Updated
2021/12/16
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2-Thiophenemethylamine Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

2-Thiophenemethylamine can be used as areactant involved in synthesis of Triazole-linked-thiopene conjugates and a biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein.

Uses

2-Thiophenemethylamine is Reactant involved in synthesis of: Triazole-linked-thiopene conjugates. It is used for biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein.It is a reactant involved in studies of organocatalyzed asymmetric reductive amination of ketones.

Uses

Reactant involved in synthesis of:

  • Triazole-linked-thiopene conjugates for use as a biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein
  • Serotonin 5-HT1A receptor antagonists which have neuroprotective affects against ischemic cell damage
  • Imidazole- and piperonyl-containing thiadiazoles and pyrimidines for use as inducible oxide synthase dimerization inhibitors
  • Optoelectronic segmented polyurethanes

Reactant involved in:
  • Studies of organocatalyzed asymmetric reductive amination of ketones
  • Metal-free aerobic oxidative coupling of amines to imines

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1389, 1946 DOI: 10.1021/ja01211a510

General Description

2-Thiophenemethylamine is a potential ligand replacement for poly(3-hexylthiophene)/CdSe hybrid solar cells.

Purification Methods

Distil the amine under reduced pressure (nitrogen), from BaO, through a column packed with glass helices. The hydrochloride has m 193-194o (from EtOH/Me2CO) and the picrate has m 181-182o. [Beilstein 18 III/IV 7096.]

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2-Thiophenemethylamine Suppliers

Zhengzhou Ruke Biological Co., Ltd.
Tel
15981811963
Fax
QQ:1410472904
Email
1410472904@qq.com
Country
China
ProdList
5825
Advantage
58
Wuhan zhijingcheng Pharmaceutical Technology Co.,Ltd
Tel
13871097899
Fax
13986215120
Email
chemistry888@126.com
Country
China
ProdList
48
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11777
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from 2-Thiophenemethylamine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Thiophenemethylamine 27757-85-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Career Henan Chemical Co
Product
2-Thiophenemethylamine 27757-85-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-23

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