ChemicalBook > CAS DataBase List > 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Product Name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- CAS No.
- 179687-79-7
- Chemical Name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Synonyms
- Neratinib Impurity 35;2-((4-chloro-3-nitrophenoxy)methyl)pyridine;2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine;Pyridine, 2-[(2-chloro-4-nitrophenoxy)methyl]-;3-Chloro-4-(2-pyridinylmethoxy)-1-nitrobenzene
- CBNumber
- CB4855383
- Molecular Formula
- C12H9ClN2O3
- Formula Weight
- 264.66
- MOL File
- 179687-79-7.mol
More
Less
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Light brown to brown Powder
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-M0296
- Product name
- 2-((2-chloro-4-nitrophenoxy)methyl)pyridine
- Packaging
- 250mg
- Price
- $104
- Updated
- 2021/12/16
AK Scientific
- Product number
- P372
- Product name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Packaging
- 250mg
- Price
- $157
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC147747
- Product name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Packaging
- 500mg
- Price
- $170
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC147747
- Product name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Packaging
- 1g
- Price
- $260
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC147747
- Product name
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
- Packaging
- 2g
- Price
- $340
- Updated
- 2021/12/16
More
Less
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine Chemical Properties,Usage,Production
Uses
3-Chloro-4-(2-pyridylmethyloxy)nitrobenzene was used to synthesize aniline ''headgroups'' and incorporat them into an alkynyl thienopyrimidine series of EGFR and ErbB-?2 inhibitors.
Synthesis
619-08-9
6959-47-3
179687-79-7
General procedure for the synthesis of 2-((2-chloro-4-nitrophenoxy)methyl)pyridine from 2-chloro-4-nitrophenol and 2-chloromethylpyridine hydrochloride: 2-chloromethylpyridine hydrochloride (16.4 g, 0.1 mol) and potassium carbonate (K2CO3, 27.6 g, 0.2 mol) were suspended in N,N-dimethylformamide (DMF, 100 mL). stirred for 30 min at room temperature. Subsequently, 2-chloro-4-nitrophenol (17.4 g, 0.1 mol) and potassium iodide (KI, 0.83 g, 5 mol%) were added, and the reaction mixture was stirred for 12 hours at 60 °C. After completion of the reaction, the reaction mixture was diluted with water (400 mL), the resulting solid was collected by filtration, washed with water and dried to afford 2-((2-chloro-4-nitrophenoxy)methyl)pyridine (26 g, 98% yield) as a white solid. The melting point of the product was 149.2-149.9 °C; mass spectra (MS-EI) m/z: 92, 229, 263 (M+).
References
[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 3090 - 3104
[2] Patent: US2016/214964, 2016, A1. Location in patent: Paragraph 0138
[3] Patent: WO2005/10008, 2005, A1. Location in patent: Page/Page column 114-115
[4] Patent: WO2006/23843, 2006, A2. Location in patent: Page/Page column 64
[5] Patent: US2010/298297, 2010, A1. Location in patent: Page/Page column 14
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine Suppliers
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3199
- Advantage
- 55
- Tel
- 021-58388037;21-58388037 13472507714
- 35177634@qq.com;1589045147@qq.com
- Country
- China
- ProdList
- 803
- Advantage
- 55
- Tel
- 0086-15189180296
- Fax
- 0086-513-81292226
- l_xu@wisdompharma.com
- Country
- China
- ProdList
- 221
- Advantage
- 60
- Tel
- 21-33585366 13311639313
- Fax
- +86-21-34979012
- sales@shyrchem.com
- Country
- China
- ProdList
- 806
- Advantage
- 55
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7552
- Advantage
- 61
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 0523-86818997 18652728585
- sales@allyrise.com
- Country
- China
- ProdList
- 2966
- Advantage
- 60
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18333
- Advantage
- 56
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 010-57903446 15869909019
- Fax
- 010-57903446
- 168931144@qq.com
- Country
- China
- ProdList
- 2875
- Advantage
- 58
- Tel
- 028-64353063
- Fax
- 028-64353063 QQ:784253935
- reacchemical@163.com
- Country
- China
- ProdList
- 5253
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0539-6362799 20）
- Fax
- 0539-6362799（To 20）
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- +86-（0）57185586718; +8613336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29735
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10295
- Advantage
- 58
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 9972
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- +8615255079626
- eric@witopchemical.com
- Country
- China
- ProdList
- 23541
- Advantage
- 58
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- +86-5922680277 +86-13806087780
- sale@simagchem.com
- Country
- China
- ProdList
- 17346
- Advantage
- 58
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- chemwill_asia@126.com
- Country
- CHINA
- ProdList
- 23912
- Advantage
- 58
- Tel
- 13969155946
- 1461866103@qq.com
- Country
- China
- ProdList
- 16111
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39927
- Advantage
- 58
- Tel
- 21-33585366
- Fax
- +86-21-34979012
- export01@shyrchem.com
- Country
- CHINA
- ProdList
- 1319
- Advantage
- 58
- Tel
- +8618523575427
- sales@conier.com
- Country
- China
- ProdList
- 49975
- Advantage
- 58
- Tel
- 16621358918
- Fax
- QQ:402135374
- botuopharma888@163.com
- Country
- China
- ProdList
- 9208
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ：2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 9991
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44894
- Advantage
- 58
- Tel
- --
- Fax
- --
- sarah@mainchem.com
- Country
- China
- ProdList
- 6547
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 18951933883
- Fax
- QQ:1665798899
- leo.feng@liftpharm.com
- Country
- China
- ProdList
- 306
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 18130062233
- 3362556465@qq.com
- Country
- China
- ProdList
- 8100
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
- Tel
- 16773308882
- 927608786@qq.com
- Country
- China
- ProdList
- 3051
- Advantage
- 58
- Tel
- 19122915778
- 1549869036@qq.com
- Country
- China
- ProdList
- 498
- Advantage
- 58
- Tel
- 15387063101
- 2881924050@qq.com
- Country
- China
- ProdList
- 9960
- Advantage
- 58
- Tel
- 15652467323
- sales@inno-chem.com.cn
- Country
- China
- ProdList
- 8293
- Advantage
- 58
- Tel
- +86(21)5895 0110 19945755304
- sales@chemany.com
- Country
- China
- ProdList
- 9984
- Advantage
- 58
- Tel
- 029-63373950 17392213970
- 1052@dideu.com
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 021-021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29784
- Advantage
- 58
- Tel
- 1173954148q
- meishipharma@126.com
- Country
- China
- ProdList
- 20033
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
- Tel
- 021-57520305 13795461237
- zhuruyan@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
- Tel
- 400-0628126 15697567703
- sales-team@aobchem.com.cn
- Country
- China
- ProdList
- 49999
- Advantage
- 58
More
Less
View Lastest Price from 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine manufacturers
Shenzhen Nexcon Pharmatechs Ltd.
- Product
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine 179687-79-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2025-04-29
Career Henan Chemical Co
- Product
- 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine 179687-79-7
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-07-31
179687-79-7, 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridineRelated Search:
Bensulfuron methyl
METSULFURON METHYL
Methyltrimethoxysilane
2,6-Lutidine
1-Chloro-3-nitrobenzene
Dimethyldimethoxysilane
4-Nitropyridine
5-Amino-2-methylpyridine
2-Chloro-4-nitropyridine
Kresoxim-methyl
2-Chloro-5-chloromethylpyridine
4-Methylpyridine
Pyridine
Methyl salicylate
Methylparaben
Thiophanate-methyl
Methyl
Methyl bromide