ChemicalBook > CAS DataBase List > 5-Methoxy-pyridin-3-ylamine

5-Methoxy-pyridin-3-ylamine

Product Name: 5-Methoxy-pyridin-3-ylamine
CAS No.: 64436-92-6
Chemical Name: 5-Methoxy-pyridin-3-ylamine
Synonyms: 5-Me;5-Methoxy-pyridin-3-;5-Methoxy-3-pyridinamine;5-Methoxypyridin-3-amine;5-Methoxy-3-aminopyridine;3-Amino-5-methoxypyridine;3-Pyridinamine, 5-methoxy-;5-Methoxy-pyridin-3-ylamine;5-Methoxy-pyridin-3-amine ,98%;5-Fluoro-2,6-dimethyl-4-pyrimidinamine
CBNumber: CB4875561
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 64436-92-6.mol

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5-Methoxy-pyridin-3-ylamine Property

Melting point:: 64-65 °C(Solv: benzene (71-43-2))
Boiling point:: 166-168 °C(Press: 15 Torr)
Density: 1.139±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 5.80±0.10(Predicted)
Appearance: Brown to reddish brown Solid
InChI: InChI=1S/C6H8N2O/c1-9-6-2-5(7)3-8-4-6/h2-4H,7H2,1H3
InChIKey: CTQPCFFQBYXOAJ-UHFFFAOYSA-N
SMILES: C1=NC=C(OC)C=C1N

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Safety

Risk Statements: 41
Safety Statements: 26-39
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 4H56-1-9H
Product name: 5-Methoxypyridin-3-amine
Purity: 95%
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA45403
Product name: 3-Amino-5-methoxypyridine
Packaging: 1g
Price: $125.5
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-9H
Product name: 5-Methoxypyridin-3-amine
Purity: 95%
Packaging: 1g
Price: $135
Updated: 2021/12/16

Matrix Scientific

Product number: 057365
Product name: 5-Methoxypyridin-3-amine
Purity: 95%
Packaging: 1g
Price: $163
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA45403
Product name: 3-Amino-5-methoxypyridine
Packaging: 2g
Price: $193.8
Updated: 2021/12/16

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5-Methoxy-pyridin-3-ylamine Chemical Properties,Usage,Production

Synthesis

50720-12-2

64436-92-6

General procedure for the synthesis of 3-bromo-5-methoxypyridine from 3-bromo-5-methoxypyridine: 3-bromo-5-methoxypyridine (500 mg, 2.66 mmol), ammonium hydroxide (15 mL), and cobalt sulfate pentahydrate (33 mg, 0.13 mmol) were placed in a hermetically sealed tube and heated in a microwave reactor for 20 hours at 140 °C. After completion of the reaction, the reaction mixture was cooled to room temperature and the crude product was subjected to liquid-liquid separation between ethyl acetate and water. The organic layer was washed sequentially with water (3 times) and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 84 mg of solid product in 25% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.72 (d, J = 5.4 Hz, 2H), 6.51 (t, J = 2.4 Hz, 1H), 3.79 (s, 3H) ppm; HPLC-MS: m/z 125.0.

References

[1] Organic Process Research and Development, 2012, vol. 16, # 5, p. 788 - 797
[2] Advanced Synthesis and Catalysis, 2013, vol. 355, # 4, p. 627 - 631
[3] European Journal of Medicinal Chemistry, 2015, vol. 106, p. 50 - 59
[4] Patent: US2007/167497, 2007, A1. Location in patent: Page/Page column 26
[5] Patent: US2014/336182, 2014, A1. Location in patent: Paragraph 0315

5-Methoxy-pyridin-3-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methoxy-pyridin-3-ylamine Suppliers

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View Lastest Price from 5-Methoxy-pyridin-3-ylamine manufacturers

Career Henan Chemical Co

Product: 3-Amino-5-methoxypyridine 64436-92-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-25

64436-92-6, 5-Methoxy-pyridin-3-ylamineRelated Search:

3-Amino-4-pyrazolecarbonitrile 2-Methylamino-3-amino-6-methoxypyridine 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 5-METHOXY-PYRIDIN-2-YLAMINE 2-Chloro-3-methoxy-5-nitropyridine 5-Methoxy-pyridin-3-ylamine 3-Amino-2,6-dibromo-5-ethoxypyridine 3-Methoxy-5-nitropyridin-2-ol 3-Amino-6-methoxypyridine-2-carboxylic acid 3-AMINO-6-METHOXY-2-METHYLAMINO-PYRIDINE, DIHYDROCHLORIDE SPECIALITY CHEMICALS 6-METHOXY-PYRIDIN-2-YLAMINE 2-Amino-3-methoxypyridine 2-METHOXY-PYRIDIN-3-YLAMINE 2-METHOXY-5-AMINOPYRIDINE 6-METHOXY-PYRIDIN-3-YLAMINE,6-METHOXY-PYRIDIN-3-YLAMINE 5-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 2,3-Diamino-6-methoxypyridine 5-AMINO-2-METHOXY-ISONICOTINIC ACID 6-Bromo-2-methoxy-pyridin-3-ylamine ,97%,6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

5-Methoxy-pyridin-3-ylamine

3-Amino-5-methoxypyridine

5-Methoxy-3-pyridinamine

5-Methoxy-3-aminopyridine

5-Methoxypyridin-3-amine

5-Methoxy-pyridin-3-amine ,98%

5-Methoxy-pyridin-3-

3-Pyridinamine, 5-methoxy-

5-Fluoro-2,6-dimethyl-4-pyrimidinamine

5-Me

64436-92-6

64436-93-2

Heterocyclic Compounds