5-Methoxy-pyridin-3-ylamine
- Product Name
- 5-Methoxy-pyridin-3-ylamine
- CAS No.
- 64436-92-6
- Chemical Name
- 5-Methoxy-pyridin-3-ylamine
- Synonyms
- 5-Me;5-Methoxy-pyridin-3-;5-Methoxy-3-pyridinamine;5-Methoxypyridin-3-amine;5-Methoxy-3-aminopyridine;3-Amino-5-methoxypyridine;3-Pyridinamine, 5-methoxy-;5-Methoxy-pyridin-3-ylamine;5-Methoxy-pyridin-3-amine ,98%;5-Fluoro-2,6-dimethyl-4-pyrimidinamine
- CBNumber
- CB4875561
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 64436-92-6.mol
5-Methoxy-pyridin-3-ylamine Property
- Melting point:
- 64-65 °C(Solv: benzene (71-43-2))
- Boiling point:
- 166-168 °C(Press: 15 Torr)
- Density
- 1.139±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 5.80±0.10(Predicted)
- Appearance
- Brown to reddish brown Solid
- InChI
- InChI=1S/C6H8N2O/c1-9-6-2-5(7)3-8-4-6/h2-4H,7H2,1H3
- InChIKey
- CTQPCFFQBYXOAJ-UHFFFAOYSA-N
- SMILES
- C1=NC=C(OC)C=C1N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4H56-1-9H
- Product name
- 5-Methoxypyridin-3-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA45403
- Product name
- 3-Amino-5-methoxypyridine
- Packaging
- 1g
- Price
- $125.5
- Updated
- 2021/12/16
- Product number
- 4H56-1-9H
- Product name
- 5-Methoxypyridin-3-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 057365
- Product name
- 5-Methoxypyridin-3-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $163
- Updated
- 2021/12/16
- Product number
- FA45403
- Product name
- 3-Amino-5-methoxypyridine
- Packaging
- 2g
- Price
- $193.8
- Updated
- 2021/12/16
5-Methoxy-pyridin-3-ylamine Chemical Properties,Usage,Production
Synthesis
50720-12-2
64436-92-6
General procedure for the synthesis of 3-bromo-5-methoxypyridine from 3-bromo-5-methoxypyridine: 3-bromo-5-methoxypyridine (500 mg, 2.66 mmol), ammonium hydroxide (15 mL), and cobalt sulfate pentahydrate (33 mg, 0.13 mmol) were placed in a hermetically sealed tube and heated in a microwave reactor for 20 hours at 140 °C. After completion of the reaction, the reaction mixture was cooled to room temperature and the crude product was subjected to liquid-liquid separation between ethyl acetate and water. The organic layer was washed sequentially with water (3 times) and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 84 mg of solid product in 25% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.72 (d, J = 5.4 Hz, 2H), 6.51 (t, J = 2.4 Hz, 1H), 3.79 (s, 3H) ppm; HPLC-MS: m/z 125.0.
References
[1] Organic Process Research and Development, 2012, vol. 16, # 5, p. 788 - 797
[2] Advanced Synthesis and Catalysis, 2013, vol. 355, # 4, p. 627 - 631
[3] European Journal of Medicinal Chemistry, 2015, vol. 106, p. 50 - 59
[4] Patent: US2007/167497, 2007, A1. Location in patent: Page/Page column 26
[5] Patent: US2014/336182, 2014, A1. Location in patent: Paragraph 0315
5-Methoxy-pyridin-3-ylamine Preparation Products And Raw materials
Raw materials
Preparation Products
5-Methoxy-pyridin-3-ylamine Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 5-Methoxy-pyridin-3-ylamine manufacturers
- Product
- 3-Amino-5-methoxypyridine 64436-92-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-25