ChemicalBook > CAS DataBase List > Polymyxin B

Polymyxin B

Product Name: Polymyxin B
CAS No.: 1404-26-8
Chemical Name: Polymyxin B
Synonyms: Polymyxin E see Colistin;polymyxin B 2.5sulfate entahydrate;Glucosamine Hydrochloride Impurity 32;Polymyxin B (base and/or unspecified salts)
CBNumber: CB4902083
Molecular Formula: C55H96N16O13
Formula Weight: 0
MOL File: Mol file

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Polymyxin B Property

alpha: 5461 -106.3° (1N HCl)
form: Solid
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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Polymyxin B Chemical Properties,Usage,Production

Description

Polymyxin B was isolated by Wellcome Research Laboratories, in 1949, from the mixture of polymyxins A, B, C, and D produced byBacillus polymyxa. It was later separated into the major component, B1, and the minor component, B2. Polymyxin B is a basic polypeptide and shows strong activity against gram-negative bacteria, but its activity against gram-positive bacteria, Mycobacterium, and fungi is weak. Because of its toxicity, it is used carefully by intramuscular injection for resistant Pseudomonas aeruginosa infections, e.g., sepsis. Polymyxin B is used orally to sterilize the gut in leukemic patients, intraspinally for meningitis, or topically.

Uses

Antibacterial Aerosporin.

Definition

ChEBI: A polymyxin having a 6-methylheptanoyl group at the amino terminus.

brand name

(GlaxoSmithKline); Poly-Rx (X Gen).

Contact allergens

Active against Gram-negative bacteria, Polymyxin B is a mixture of Polymyxin B1 and B2. Sensitization occurs by topical, ophthalmic, and otic preparations. Cosensitization is frequent with other topical antibiotics like neomycin or bacitracin.

Polymyxin B Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polymyxin B manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Polymyxin B2 1404-26-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-11

Firsky International Trade (Wuhan) Co., Ltd

Product: Polymyxin B 1404-26-8
Price: US $30.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2023-09-26

Hebei Fengqiang Trading Co., LTD

Product: Polymyxin B 1404-26-8
Price: US $100.00/bag
Min. Order: 1bag
Purity: 99
Supply Ability: 5000
Release date: 2023-09-12

1404-26-8, Polymyxin B Related Search:

Ethyl isocyanoacetate Benzyl isocyanide N-BUTYLISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) PHENYLSELENOL Aluminum acetylacetonate SALCOMINE Cupric acetylacetonate Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) COBALT(II) ACETYLACETONATE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE Tris(2,4-pentanedionato)chroMiuM(III) TERT-BUTYL ISOCYANIDE METHYL ISOCYANOACETATE Polymyxin B sulfate

polymyxin B 2.5sulfate entahydrate

Polymyxin B (base and/or unspecified salts)

Polymyxin E see Colistin

Glucosamine Hydrochloride Impurity 32

1404-26-8

C43H82N16O12