Ethyl 4-bromophenylacetate
- Product Name
- Ethyl 4-bromophenylacetate
- CAS No.
- 14062-25-0
- Chemical Name
- Ethyl 4-bromophenylacetate
- Synonyms
- ethyl 2-(4-broMophenyl)acetate;4-bromophenylacetic acid ethyl ester;4-broMoethyl acetate;ETHYL 4-BROMOPHENYLACETATE;ETHYL P-BROMOPHENYLACETATE;2-(4-bromophenyl)butanoate;Ethyl4-Bromophenylacetate>Ethyl 4-bromophenylacetate,99%;Ethyl 4-bromophenylacetate 99%;Ethyl 4-bromophenylacetate ,97%
- CBNumber
- CB5109173
- Molecular Formula
- C10H11BrO2
- Formula Weight
- 243.1
- MOL File
- 14062-25-0.mol
Ethyl 4-bromophenylacetate Property
- Melting point:
- 29-33 °C(lit.)
- Boiling point:
- 88-90°C 0,35mm
- Density
- 1.389±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid or Low Melting Solid
- color
- Clear colorless to pale yellow
- InChI
- InChI=1S/C10H11BrO2/c1-2-13-10(12)7-8-3-5-9(11)6-4-8/h3-6H,2,7H2,1H3
- InChIKey
- ZFDCWHPNBWPPHG-UHFFFAOYSA-N
- SMILES
- C1(CC(OCC)=O)=CC=C(Br)C=C1
- CAS DataBase Reference
- 14062-25-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 631353
- Product name
- Ethyl 4-bromophenylacetate
- Purity
- 97%
- Packaging
- 5g
- Price
- $34.05
- Updated
- 2025/07/31
- Product number
- 631353
- Product name
- Ethyl 4-bromophenylacetate
- Purity
- 97%
- Packaging
- 25g
- Price
- $70.8
- Updated
- 2025/07/31
- Product number
- E0903
- Product name
- Ethyl 4-Bromophenylacetate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- E0903
- Product name
- Ethyl 4-Bromophenylacetate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $58
- Updated
- 2025/07/31
- Product number
- B680110
- Product name
- 4-Bromo-benzeneaceticAcidEthylEster
- Packaging
- 25g
- Price
- $160
- Updated
- 2021/12/16
Ethyl 4-bromophenylacetate Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to pale yellow liquid
Uses
4-Bromo-benzeneacetic Acid Ethyl Ester is used to prepare highly selective and orally active Lysophosphatidic Acid (LPA) receptor-1 antagonists with potent activity on human lung fibroblasts.
Synthesis
64-17-5
1878-68-8
14062-25-0
Preparation of the intermediate 1-bromo-4-(2-methoxy-2-methyldienyl)benzene (1AG-1): 2-(4-bromophenyl)acetic acid (75 g, 340 mmol) was suspended in ethanol (341 mL). Concentrated sulfuric acid (0.682 mL, 12.79 mmol) was added slowly and the reaction mixture was subsequently heated to reflux and maintained for 24 hours. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The residue was diluted with ether and saturated sodium bicarbonate solution for acid-base neutralization. The organic and aqueous layers were carefully separated and the organic layer was subsequently washed with brine and dried over sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated to give ethyl 2-(4-bromophenyl)acetate (80.2 g, 97% yield) as an off-white solid.
References
[1] Patent: WO2010/86820, 2010, A1. Location in patent: Page/Page column 53
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 21, p. 6665 - 6681
[3] Patent: US2013/79320, 2013, A1. Location in patent: Paragraph 0473; 0474
[4] Patent: WO2013/45451, 2013, A1. Location in patent: Paragraph 51
[5] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 714 - 723
Ethyl 4-bromophenylacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl 4-bromophenylacetate manufacturers
- Product
- Ethyl 4-bromophenylacetate 14062-25-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04
- Product
- Ethyl 4-bromophenylacetate 14062-25-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26
- Product
- Ethyl 4-bromophenylacetate 14062-25-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-09