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LICOCHALCONE-A

Product Name
LICOCHALCONE-A
CAS No.
58749-22-7
Chemical Name
LICOCHALCONE-A
Synonyms
CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Licochalcone A (10mg)
CBNumber
CB5114580
Molecular Formula
C21H22O4
Formula Weight
338.4
MOL File
58749-22-7.mol
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LICOCHALCONE-A Property

Melting point:
100°
Boiling point:
532.6±50.0 °C(Predicted)
Density 
1.171±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka
7.82±0.15(Predicted)
form 
Yellow solid
color 
Yellow-orange
BRN 
4534154
InChIKey
KAZSKMJFUPEHHW-DHZHZOJOSA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37
WGK Germany 
3
RTECS 
UB8755000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80486
Product name
Licochalcone A
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$595
Updated
2024/03/01
Sigma-Aldrich
Product number
435800
Product name
Licochalcone-A, Synthetic
Packaging
10mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
435800
Product name
Licochalcone-A, Synthetic
Packaging
50mg
Price
$404
Updated
2024/03/01
Cayman Chemical
Product number
11853
Product name
Licochalcone A
Purity
≥95%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
11853
Product name
Licochalcone A
Purity
≥95%
Packaging
10mg
Price
$93
Updated
2024/03/01
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LICOCHALCONE-A Chemical Properties,Usage,Production

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Definition

ChEBI: Licochalcone A is a member of chalcones.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

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LICOCHALCONE-A Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Sequoia Research Products Ltd.
Tel
--
Fax
--
Email
sales@seqchem.com
Country
United Kingdom
ProdList
3113
Advantage
69
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
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View Lastest Price from LICOCHALCONE-A manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Licochalcone a Powder 58749-22-7
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-18
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Licochalcone a Powder 58749-22-7
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-18
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
LICOCHALCONE-A 58749-22-7
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
≥98%
Supply Ability
20tons
Release date
2024-01-03

58749-22-7, LICOCHALCONE-ARelated Search:


  • LICOCHALCONE-A
  • (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE
  • 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
  • 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • 7-Dimethoxycoumarin
  • Licochalcone A, >=98%
  • Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A
  • Licochalcone A, >99%
  • CS-919
  • Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem
  • (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licocgalcone-A
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
  • 4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone
  • (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Glycyrrhiza chalcone A
  • Licorice Chalcone A
  • Licoricchalcone A
  • Licochalcone A (10mg)
  • Licochalcone A-RM
  • Licochalcone a Powder
  • 58749-22-7
  • The group of Liquorice
  • sy
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract