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10-Hydroxydecanoic acid

Product Name
10-Hydroxydecanoic acid
CAS No.
1679-53-4
Chemical Name
10-Hydroxydecanoic acid
Synonyms
NSC 15139;10-hydroxycapricaci;10-Hydroxycapricacid;1-Hydroxydecanoic acid;10-HYDROXYDECANOIC ACID;10-HYDROXY-DECYLIC ACID;Decanoic acid, 10-hydroxy-;10-HYDROXYDECANOIC ACID 95%;10-Hydroxydecanoic acid, 95+%;E-10-hydroxy-2-decylennic acid
CBNumber
CB5146543
Molecular Formula
C10H20O3
Formula Weight
188.26
MOL File
1679-53-4.mol
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10-Hydroxydecanoic acid Property

Melting point:
75-77 °C (lit.)
Boiling point:
330.8±15.0 °C(Predicted)
Density 
1.013±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
4.78±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C10H20O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h11H,1-9H2,(H,12,13)
InChIKey
YJCJVMMDTBEITC-UHFFFAOYSA-N
SMILES
C(O)(=O)CCCCCCCCCO
LogP
1.847 (est)
CAS DataBase Reference
1679-53-4(CAS DataBase Reference)
NIST Chemistry Reference
10-Hydroxydecanoic acid(1679-53-4)
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Safety

Hazard Codes 
Xi
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2918199890
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
379700
Product name
10-Hydroxydecanoic acid
Purity
technical grade
Packaging
500mg
Price
$102
Updated
2023/06/20
Sigma-Aldrich
Product number
379700
Product name
10-Hydroxydecanoic acid
Purity
technical grade
Packaging
5g
Price
$144
Updated
2023/06/20
TCI Chemical
Product number
H1090
Product name
10-Hydroxydecanoic Acid
Purity
min. 97.0 %
Packaging
5G
Price
$66
Updated
2025/07/31
TCI Chemical
Product number
H1090
Product name
10-Hydroxydecanoic Acid
Purity
min. 97.0 %
Packaging
25G
Price
$197
Updated
2025/07/31
Cayman Chemical
Product number
30458
Product name
10-hydroxy Decanoic Acid
Packaging
1g
Price
$56
Updated
2024/03/01
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10-Hydroxydecanoic acid Chemical Properties,Usage,Production

Chemical Properties

Crystals. Melting point 75.5-76.5℃.

Uses

Reactant involved in: • ;Synthesis of copolymers of acrylamide and sodium acryloyloxydecanoate1• ;Macrolactonization for preparation of Sansalvamide A2• ;Studies of chain length selectivity for cutinase catalyzed polycondensation reactions3• ;Ruthenium-catalyzed esterification followed by macrocyclization4• ;Synthesis of anhydrides and esters5

Uses

10-Hydroxydecanoic acid is suitable for use in a study on Novozym 435-catalyzed condensation polymerization of cis-9,10-epoxy-18-hydroxyoctadecanoic acid and its comparison with corresponding polymerization of 10-hydroxydecanoic acid.

Definition

ChEBI: A 10-carbon, omega-hydroxy fatty acid, shown to be the preferred hydroxylation product (together with the 9-OH isomer) of capric acid in biosystems, and used as a standard in lipid assays; reported to have cytotoxic effects.

General Description

10-Hydroxydecanoic acid (10-HDA) is a saturated fatty acid of hydroxy-trans-2-decenoic acid (10H2DA). Its molecule has two functional groups (-OH and -COOH). It has been reported to prevent the lipopolysaccharide-induced NO production in murine macrophages. 10-HDA has been extracted from royal jelly obtained from honeybees (Apis mellifera) and exhibits estrogenic action. Its polymerization with the polyethylene glycol-modified lipase in a transparent benzene solution has been reported to proceed by the formation of ester linkage.

in vivo

10-Hydroxydecanoic acid (1 mol/L; Intranasal injection 100 μL; once daily for 3 days) increases the number of microfold cells (M cells) in the epithelium lining the luminal surface of the nasopharyngeal-associated lymphoid tissue (NALT) in cynomolgus monkeys[2]. 10-Hydroxydecanoic acid (2.4 mg; p.o.; enteric-coated capsules taken orally once a day for 20 days) increases the number of M cells and improves the level of antigen-specific immunoglobulin A (IgA) in the follicle-associated epithelium (FAE) covering Peyer’s patches (PPs) in cynomolgus monkeys[2].

Animal Model:cynomolgus macaque [2]
Dosage:1 mol/L, Administer 100 μL
Administration:Intranasal administration; once a day for 3 days
Result:Increased number of gp2-positive cells in the epithelium overlying NALT follicles.
Animal Model:cynomolgus macaque [2]
Dosage:2.4 mg
Administration:p.o.; enteric-coated capsules once a day for 20 days
Result:Increased the number of gp2-positive M cells.
10-HDAA (2.4 mg) enteric-coated capsules containing poliovirus antigen (106 TCID50) induced poliovirus- and influenza virus-specific IgAs on day 12 after oral administration.

10-Hydroxydecanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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10-Hydroxydecanoic acid Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
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View Lastest Price from 10-Hydroxydecanoic acid manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
10-Hydroxydecanoic acid 1679-53-4
Price
US $500.00-300.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-23
Hebei Chuanghai Biotechnology Co., Ltd
Product
10-Hydroxydecanoic acid 1679-53-4
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05
Hebei Yanxi Chemical Co., Ltd.
Product
10-Hydroxydecanoic acid 1679-53-4
Price
US $20.00-3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-20

1679-53-4, 10-Hydroxydecanoic acidRelated Search:


  • 10-Hydroxycapricacid
  • 10-HYDROXYDECANOIC ACID
  • 10-Hydroxydecanoic acid (Synonyms: NSC 15139)
  • 1-Hydroxydecanoic acid
  • 10-Hydroxydecanoic acid (NSC 15139)
  • Decanoic acid, 10-hydroxy-
  • 10-HYDROXY-DECYLIC ACID
  • 10-HYDROXYDECANOIC ACID 95%
  • E-10-hydroxy-2-decylennic acid
  • NSC 15139
  • 10-Hydroxydecanoic acid technical grade
  • 10-Hydroxydecanoic acid, 95+%
  • 10-hydroxycapricaci
  • 1679-53-4
  • HOCH29COOH
  • HOCH29CO2H
  • HOCH2CH28COOH
  • CARBOXYLIC ACID
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • C10
  • Organic Building Blocks
  • Biochemicals and Reagents
  • Building Blocks
  • C10
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Fatty Acids and conjugates
  • Fatty Acyls
  • Hydroxy Fatty Acids
  • Lipids
  • Organic Building Blocks
  • C10Fatty Acids
  • Carbonyl Compounds
  • Carboxylic Acids
  • Hydroxy fatty acids
  • Saturated fatty acids and derivatives