ChemicalBook > CAS DataBase List > 4'-Fluoro-2'-hydroxyacetophenone

4'-Fluoro-2'-hydroxyacetophenone

Product Name
4'-Fluoro-2'-hydroxyacetophenone
CAS No.
1481-27-2
Chemical Name
4'-Fluoro-2'-hydroxyacetophenone
Synonyms
1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one;1-(4-fluoro-2-hydroxyphenyl)ethanone;4-FLUORO-2-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxy;4-FLUORO-2-HYDROXYACETOPHE;uoro-2'-hydroxyacetophenone;4'-FLUORO-2'-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxyacetophenone;4'-Fluoro-2'-hydroxyacetophenone98%;4'-Fluoro-2'-hydroxyacetophenone>
CBNumber
CB5147045
Molecular Formula
C8H7FO2
Formula Weight
154.14
MOL File
1481-27-2.mol
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4'-Fluoro-2'-hydroxyacetophenone Property

Melting point:
32-34°C
Boiling point:
65°C 2mm
Density 
1.1850 (estimate)
Flash point:
98°C
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to lump
pka
9.17±0.10(Predicted)
color 
White to Almost white
BRN 
2249799
InChIKey
HLTBTUXAMVOKIH-UHFFFAOYSA-N
CAS DataBase Reference
1481-27-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29147000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
466964
Product name
4′-Fluoro-2′-hydroxyacetophenone
Purity
98%
Packaging
5g
Price
$53.9
Updated
2024/03/01
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
5g
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
25g
Price
$243
Updated
2024/03/01
Alfa Aesar
Product number
A16030
Product name
4'-Fluoro-2'-hydroxyacetophenone, 98%
Packaging
5g
Price
$58.65
Updated
2024/03/01
Alfa Aesar
Product number
A16030
Product name
4'-Fluoro-2'-hydroxyacetophenone, 98%
Packaging
25g
Price
$210.65
Updated
2024/03/01
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4'-Fluoro-2'-hydroxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellow liquid

Uses

4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

Preparation

Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%).

General Description

4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.

4'-Fluoro-2'-hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Fluoro-2'-hydroxyacetophenone Suppliers

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View Lastest Price from 4'-Fluoro-2'-hydroxyacetophenone manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Career Henan Chemical Co
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

1481-27-2, 4'-Fluoro-2'-hydroxyacetophenoneRelated Search:


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  • 4-FLUORO-2-HYDROXYACETOPHENONE
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  • 4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone
  • 4-FLUORO-2-HYDROXYACETOPHE
  • uoro-2'-hydroxyacetophenone
  • 1-(4-fluoro-2-hydroxyphenyl)ethanone
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  • 4'-Fluoro-2'-hydroxyacetophenone&gt
  • Ethanone, 1-(4-fluoro-2-hydroxyphenyl)-
  • 4'-Fluoro-2'-hydroxyacetophenone
  • 1481-27-2
  • 1181-27-2
  • FC6H3OHCOCH3
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C7 to C8
  • Aromatic Acetophenones & Derivatives (substituted)
  • ketone
  • Adehydes, Acetals & Ketones
  • Fluorine Compounds
  • Phenols
  • C7 to C8
  • Carbonyl Compounds
  • Ketones