ChemicalBook > CAS DataBase List > 4'-Fluoro-2'-hydroxyacetophenone

4'-Fluoro-2'-hydroxyacetophenone

Product Name
4'-Fluoro-2'-hydroxyacetophenone
CAS No.
1481-27-2
Chemical Name
4'-Fluoro-2'-hydroxyacetophenone
Synonyms
1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one;1-(4-fluoro-2-hydroxyphenyl)ethanone;4-FLUORO-2-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxy;4-FLUORO-2-HYDROXYACETOPHE;uoro-2'-hydroxyacetophenone;4-Fluoro-2-hydroxyacethophenone;4'-Fluoro-2'-hydroxyacetophenone;4'-Fluoro-2'-hydroxyacetophenone>4'-Fluoro-2'-hydroxyacetophenone98%
CBNumber
CB5147045
Molecular Formula
C8H7FO2
Formula Weight
154.14
MOL File
1481-27-2.mol
More
Less

4'-Fluoro-2'-hydroxyacetophenone Property

Melting point:
32-34°C
Boiling point:
65°C 2mm
Density 
1.1850 (estimate)
Flash point:
98°C
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to lump
pka
9.17±0.10(Predicted)
color 
White to Almost white
BRN 
2249799
InChI
InChI=1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3
InChIKey
HLTBTUXAMVOKIH-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(F)C=C1O)C
CAS DataBase Reference
1481-27-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29147000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
466964
Product name
4′-Fluoro-2′-hydroxyacetophenone
Purity
98%
Packaging
5g
Price
$52.82
Updated
2025/07/31
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
5g
Price
$61
Updated
2025/07/31
TCI Chemical
Product number
F0723
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
>97.0%(GC)
Packaging
25g
Price
$243
Updated
2025/07/31
TRC
Product number
F597380
Product name
4''-Fluoro-2''-hydroxyacetophenone
Packaging
5g
Price
$75
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK160426
Product name
4'-Fluoro-2'-hydroxyacetophenone
Purity
98%
Packaging
5g
Price
$77
Updated
2021/12/16
More
Less

4'-Fluoro-2'-hydroxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellow liquid

Uses

4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

Preparation

Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%).

General Description

4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.

4'-Fluoro-2'-hydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4'-Fluoro-2'-hydroxyacetophenone Suppliers

Americas 1 Austria 1 China 208 Europe 3 France 1 Germany 4 India 13 Italy 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 16 United States 29 Global 280
Taizhou Wealsun Biotech Co., Ltd
Tel
18351140886
Email
wealsunbio@126.com
Country
China
ProdList
106
Advantage
58
Suzhou Lyran Biopharma And Technology CO.,LTD.
Tel
18949975665
Email
1184800090@qq.com
Country
China
ProdList
347
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Beijing Eternalchem Co,. Ltd.
Tel
010-59484199 18611897322
Email
sales@eternalchem.com
Country
China
ProdList
4383
Advantage
60
Hangzhou Disynthesis Chemical Technology Co., Ltd.
Tel
+86-0571-88194596 15558156576
Fax
0571-88199298
Email
sales@disynchem.com
Country
China
ProdList
94
Advantage
55
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
3997
Advantage
55
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Ascepion Pharmaceuticals, Inc.
Tel
+86-512-86881668
Fax
+86-512-62956001
Country
China
ProdList
100
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Suzhou Ryan Pharmachem Technology Co.,Ltd
Tel
0512-66585217 13962137180
Fax
0512-82177549
Email
sales@ryanchem.com
Country
China
ProdList
384
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Hangzhou Dechem Tech Co.，Ltd
Tel
86-0571-87649320
Fax
86-0571-87649320
Email
dechem@aliyun.com
Country
China
ProdList
162
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Taizhou FRIEND Chemical Co., Ltd.
Tel
025-0523-86200082 15380713688
Fax
0523-86200991
Email
Austin@fredchem.cn
Country
China
ProdList
151
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
More
Less

View Lastest Price from 4'-Fluoro-2'-hydroxyacetophenone manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Career Henan Chemical Co
Product
4'-Fluoro-2'-hydroxyacetophenone 1481-27-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

1481-27-2, 4'-Fluoro-2'-hydroxyacetophenoneRelated Search:

3-Nitroacetophenone 2'-Hydroxyacetophenone Acetophenone 2',6'-Dihydroxyacetophenone 4-Nitroacetophenone 2,4-Dihydroxyacetophenone 4-Aminoacetophenone 2',4',6'-Trihydroxyacetophenone monohydrate 4-Ethyl-5-fluoro-6-hydroxypyrimidine 4'-Hydroxyacetophenone 3,5-Dihydroxyacetophenone 2-HYDROXYACETOPHENONE 3'-Hydroxyacetophenone 4-FLUORO-2-METHOXYACETOPHENONE 7-Fluoro-4-chromanone Fluorine 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone 6-Fluoro-3(2H)-benzofuranone

  • 4-FLUORO-2-HYDROXYACETOPHENONE
  • 4-Fluoro-2-hydroxyacethophenone, 98%
  • 4'-Fluoro-2'-hydroxyacetophenone 98%
  • 4'-Fluoro-2'-hydroxyacetophenone98%
  • 4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone
  • 4-FLUORO-2-HYDROXYACETOPHE
  • uoro-2'-hydroxyacetophenone
  • 1-(4-fluoro-2-hydroxyphenyl)ethanone
  • 4'-Fluoro-2'-hydroxy
  • 1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one
  • 4'-Fluoro-2'-hydroxyacetophenone&gt
  • Ethanone, 1-(4-fluoro-2-hydroxyphenyl)-
  • 4'-Fluoro-2'-hydroxyacetophenone
  • 4-Fluoro-2-hydroxyacethophenone
  • 1481-27-2
  • 1181-27-2
  • FC6H3OHCOCH3
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C7 to C8
  • Aromatic Acetophenones & Derivatives (substituted)
  • ketone
  • Adehydes, Acetals & Ketones
  • Fluorine Compounds
  • Phenols
  • C7 to C8
  • Carbonyl Compounds
  • Ketones