Jaceosidin

Product Name: Jaceosidin
CAS No.: 18085-97-7
Chemical Name: Jaceosidin
Synonyms: Jacosidin;Jaseosidin;JACEOSIDIN;Jacesiolin;Jaceosidin-RM;Brown centaurin;Jaceosidin, 98%min;Jaceosidin, 10 mM in DMSO;6-Hydroxyluteolin 3',6-dimethyl ether;4',5,7-Trihydroxy-3',6-dimethoxyflavone
CBNumber: CB51515205
Molecular Formula: C17H14O7
Formula Weight: 330.29
MOL File: 18085-97-7.mol

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Jaceosidin Property

Melting point:: 259-260 °C
Boiling point:: 619.0±55.0 °C(Predicted)
Density: 1.483±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly)
form: Solid
pka: 6.47±0.40(Predicted)
color: Pale Yellow to Light Yellow
Stability:: Hygroscopic
InChI: InChI=1S/C17H14O7/c1-22-13-5-8(3-4-9(13)18)12-6-10(19)15-14(24-12)7-11(20)17(23-2)16(15)21/h3-7,18,20-21H,1-2H3
InChIKey: GLAAQZFBFGEBPS-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(O)C(OC)=C2)OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1
LogP: 1.300 (est)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19758
Product name: Jaseosidin
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 19758
Product name: Jaseosidin
Purity: ≥98%
Packaging: 5mg
Price: $150
Updated: 2024/03/01

Cayman Chemical

Product number: 19758
Product name: Jaseosidin
Purity: ≥98%
Packaging: 10mg
Price: $264
Updated: 2024/03/01

Cayman Chemical

Product number: 19758
Product name: Jaseosidin
Purity: ≥98%
Packaging: 25mg
Price: $576
Updated: 2024/03/01

Usbiological

Product number: 300511
Product name: Jaceosidin
Packaging: 10mg
Price: $546
Updated: 2021/12/16

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Jaceosidin Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the leaves of Ailanthus, long-leaved arnica flowers, silver artemisia above ground, stevia, the leaves of the ground yellow, the above ground parts of the vine.

Uses

Jaceosidin exhibits anti-allergic, anti-inflammatory and apoptosis inducing activities.

Definition

ChEBI: A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apo tosis inducing activties.

in vivo

Jaceosidin (10 and 20 mg/kg, p.o., once a day for 3 days) blocks carrageenan-induced increase in leukocyte number and protein levels in air pouch exudates in mice^[3].
? Jaceosidin (10, 20 mg/kg, p.o.) suppresses COX-2 expression and NF-κB activation in mice^[3].
? Jaceosidin (20 mg/kg, p.o. for 2 hours) reduces hind paw edema volume in rats^[3].

Animal Model:	5-week-old male BALB/c mice (23-26 g)^[3]
Dosage:	10 and 20 mg/kg
Administration:	P.O. once a day for 3 days
Result:	Decreased the volumes of exudates (inflammatory markers), cell number and protein levels. Inhibited TNF-α by 46.7% and 50.8%, IL-1β by 46.0% and 44.7%, and PGE2 by 21.7% and 16.9%, respectively, at 20 mg/kg. Blocked COX-2 expression and NF-κB activation.

Animal Model:	Male Sprague-Dawley rats (180-200 g)^[3]
Dosage:	20 mg/kg
Administration:	P.O., for 2 hour
Result:	Reduced hind paw edema volume by 27.1% at 1 h, and 24.0% at 2 h, respectively.

IC 50

Bax; COX-2

Jaceosidin Preparation Products And Raw materials

Raw materials

Preparation Products

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Jaceosidin Suppliers

China 209 India 1 United Kingdom 1 United States 15 USA 1 Global 227

AdooQ BioScience, LLC

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ALB Technology Limited

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EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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BOC Sciences

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Protheragen-ING

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Aladdin Scientific

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TargetMol Chemicals Inc.

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ApexBio Technology

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Ivy Fine Chemicals

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Cayman Chemical Company

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United States Biological

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MedChemExpress

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Matrix Scientific

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FortopChem Technology Limited

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View Lastest Price from Jaceosidin manufacturers

Hebei Dangtong Import and export Co LTD

Product: Jaceosidin 18085-97-7
Price: US $1000.00-870.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100Tons
Release date: 2023-09-21

Hangzhou ICH Biofarm Co., Ltd

Product: Jaceosidin 18085-97-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98% HPLC
Supply Ability: 500kg
Release date: 2023-07-06

Shanghai Standard Technology Co., Ltd.

Product: Jaceosidin 18085-97-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-13

18085-97-7, JaceosidinRelated Search:

ASTRAGALIN HARRINGTONINE Isoastragaloside II poricoic acid A 3-methyl ester Poricoic acid A(F) Asiaticoside (-)-Huperzine A MONOCROTALINE Wogonin CYANIDIN CHLORIDE Pterostilbene Glycidyl Palmitate KYVUJPJYTYQNGJ-XBHHEOLKSA-N CETYL PALMITATE SHIONONE Streptonigrin CHLOROPHYLL Paclitaxel

JACEOSIDIN

3',6-Dimethoxy-4',5,7-trihydroxyflavone

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

6-Hydroxyluteolin 3',6-dimethyl ether

Jacesiolin

4',5,7-Trihydroxy-3',6-dimethoxyflavone

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-

5,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-6-methoxy-chromen-4-one

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-chromen-4-one

Jaseosidin

4',5,7-Trihydroxy-3',6-dimethoxyflavone 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxychromen-4-one

Jacosidin

Brown centaurin

Jaceosidin-RM

Jaceosidin, 10 mM in DMSO

Jaceosidin, 98%min

18085-97-7

8085-97-7

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract