Azosemide

Product Name: Azosemide
CAS No.: 27589-33-9
Chemical Name: Azosemide
Synonyms: Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP
CBNumber: CB5200179
Molecular Formula: C12H11ClN6O2S2
Formula Weight: 370.84
MOL File: 27589-33-9.mol

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Azosemide Property

Melting point:: 218-221°
Boiling point:: 221°C (rough estimate)
Density: 1.6843 (rough estimate)
refractive index: 1.6100 (estimate)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 3.58±0.10(Predicted)
color: Crystals
CAS DataBase Reference: 27589-33-9(CAS DataBase Reference)

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Safety

Toxicity: LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A965145
Product name: Azosemide
Packaging: 10g
Price: $845
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001575
Product name: AZOSEMIDE
Purity: 95.00%
Packaging: 100MG
Price: $727.65
Updated: 2021/12/16

AK Scientific

Product number: E592
Product name: Azosemide
Packaging: 100mg
Price: $298
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA44032
Product name: Azosemide
Packaging: 10mg
Price: $40
Updated: 2021/12/16

ChemScene

Product number: CS-0028137
Product name: Azosemide
Purity: >98.0%
Packaging: 10mg
Price: $50
Updated: 2021/12/16

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Azosemide Chemical Properties,Usage,Production

Description

Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.

Originator

Boehringer Manheim (W. Germany)

Uses

Diuretic.

Uses

Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.

Manufacturing Process

The 4-chloro-5-sulfamoyl-2-thenylaminobenzonitrile used as starting material is obtained by the reaction of 4-chloro-2-fluoro-5-sutfamoyl-benzonitrile with thenylamine in anhydrous tetrahydrofuran.
Then the 5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)phenyltetrazole (MP 218° to 221°C, yield 37% of theory) is obtained by the reaction of 4-chloro-5- sulfamoyl-2-thenylaminobenzonitrite (MP 170° to 174°C) with sodium azide and ammonium chloride,

brand name

LURET

Therapeutic Function

Diuretic

Safety Profile

Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl^-, SOx,and NOx.

Azosemide Preparation Products And Raw materials

Raw materials

Sodium azide Benzonitrile 2-thiophene

Preparation Products

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Azosemide Suppliers

China 84 Europe 3 India 3 South Korea 1 United Kingdom 5 United States 14 Global 110

Hubei XinRunde Chemical Co., Ltd.

Tel: 027-83214668 13545017210
Fax: 02783214688
Email: 13545017210@163.com
Country: China
ProdList: 10
Advantage: 58

Tianjin Zhongxin Chemtech Co., Ltd.

Tel: 022-66880623
Fax: 86(0)22-66880086
Email: sales@tjzxchem.com
Country: China
ProdList: 613
Advantage: 60

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 2024
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

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View Lastest Price from Azosemide manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: Azosemide 27589-33-9
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-10-09

Hubei Langyou International Trading Co., Ltd

Product: Azosemide 27589-33-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000kg
Release date: 2021-09-01

Henan Bao Enluo International TradeCo.，LTD

Product: Azosemide 27589-33-9
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-06-16

27589-33-9, AzosemideRelated Search:

Boc-D-Glutamine 2,3,5-Triphenyltetrazolium chloride 1H-Tetrazole-1-acetic acid N,N-Dimethylformamide Acrylamide Tetrazole Polyacrylamide Sulfanilamide Nitrotetrazolium blue chloride 3-Aminobenzenesulfonamide Acetamide Epichlorohydrin Polyamide Chlorantraniliprole Nicotinamide Formamide Difluorochloromethane Chloroacetic acid

2-chloro-5-(1h-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-benzenesulfonamid

2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenyl-sulfanilamid

SK-110

2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide

2-chloro-5-(2H-tetrazol-5-yl)-4-(2-thienylmethylamino)benzenesulfonamide

2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide

Azosemide Solution, 1000ppm

Azosemide Solution, 100ppm

Pharmaceutical Intermediate 98% Research Powder cas 27589-33-9 Azosemide

2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenylsulfanilamide

5-(4’-chloro-5’-sulfamoyl-2’-thenylaminophenyl)-tetrazole

azosemid

ple1053

AZOSEMIDE

2-chloro-5-(1h-tetrazol-5-yl)-4-(2-thenylamino)benzenesulphonamide

2-CHLORO-5-(1H-TETRAZOL-5-YL)-4-((2-THIENYLMETHYL)AMINO)-BENZENESULFONAMIDE

Azosemide(Chemical Name: 2-Chloro-5-(1h-Tertrazol-5-Yl)-N4-(2-Thenyl))

AZOSEMIDE HPLC

Diart

Diurapid

Luret

2-Chloro-5-(1H-tetrazol-5-y1)-4-[(2-thienylmethyl)amino]benzenesulfona-Mide

Azosemidum

Pharmaceutical Intermediate 98% Research Powder Azosemide

Benzenesulfonamide, 2-chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]-

Azosemide USP/EP/BP

2-Chloro-5-(1H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide

27589-33-9

C12H11CIN6O2S2

C12H11ClN6O2S2