Azosemide
- Product Name
- Azosemide
- CAS No.
- 27589-33-9
- Chemical Name
- Azosemide
- Synonyms
- Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP
- CBNumber
- CB5200179
- Molecular Formula
- C12H11ClN6O2S2
- Formula Weight
- 370.84
- MOL File
- 27589-33-9.mol
Azosemide Property
- Melting point:
- 218-221°
- Boiling point:
- 221°C (rough estimate)
- Density
- 1.6843 (rough estimate)
- refractive index
- 1.6100 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 3.58±0.10(Predicted)
- color
- Crystals
- CAS DataBase Reference
- 27589-33-9(CAS DataBase Reference)
Safety
- Toxicity
- LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- A965145
- Product name
- Azosemide
- Packaging
- 10g
- Price
- $845
- Updated
- 2021/12/16
- Product number
- API0001575
- Product name
- AZOSEMIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $727.65
- Updated
- 2021/12/16
- Product number
- E592
- Product name
- Azosemide
- Packaging
- 100mg
- Price
- $298
- Updated
- 2021/12/16
- Product number
- FA44032
- Product name
- Azosemide
- Packaging
- 10mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- CS-0028137
- Product name
- Azosemide
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
Azosemide Chemical Properties,Usage,Production
Description
Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.
Originator
Boehringer Manheim (W. Germany)
Uses
Diuretic.
Uses
Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.
Definition
ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.
Manufacturing Process
The 4-chloro-5-sulfamoyl-2-thenylaminobenzonitrile used as starting material
is obtained by the reaction of 4-chloro-2-fluoro-5-sutfamoyl-benzonitrile with
thenylamine in anhydrous tetrahydrofuran.
Then the 5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)phenyltetrazole (MP 218°
to 221°C, yield 37% of theory) is obtained by the reaction of 4-chloro-5-
sulfamoyl-2-thenylaminobenzonitrite (MP 170° to 174°C) with sodium azide
and ammonium chloride,
brand name
LURET
Therapeutic Function
Diuretic
Safety Profile
Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl-, SOx,and NOx.
Azosemide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Azosemide manufacturers
- Product
- Azosemide 27589-33-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2021-09-01
- Product
- Azosemide 27589-33-9
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-08
- Product
- Azosemide 27589-33-9
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2023-10-09