Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
- Product Name
- Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
- CAS No.
- 60421-23-0
- Chemical Name
- Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
- Synonyms
- Nsc161119;AC5C-OMe HCl;cycloeucinemethyl ester HCL;Cycloleucine Methyl EsteroHCl;CYCLOLEUCINE METHYL ESTER HCL;Cycloeucine methyl ester hydrochloride;Cycloleucine Methyl Ester Hydrochloride;METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL;methyl 1-aminocyclopentanecarboxylate, HCl;Methyl-1-aminocyclopentanecarboxylate hydrochloride
- CBNumber
- CB5201792
- Molecular Formula
- C7H14ClNO2
- Formula Weight
- 179.64
- MOL File
- 60421-23-0.mol
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Property
- Melting point:
- 207-208 °C (decomp)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- color
- White to Almost white
- InChI
- InChI=1S/C7H13NO2/c1-10-6(9)7(8)4-2-3-5-7/h2-5,8H2,1H3
- InChIKey
- VLNNACMZTDZCFH-UHFFFAOYSA-N
- SMILES
- C1(N)(CCCC1)C(=O)OC
Safety
- HS Code
- 2902190000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M2351
- Product name
- Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- M2351
- Product name
- Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $108
- Updated
- 2025/07/31
- Product number
- M286653
- Product name
- Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 076601
- Product name
- Cycloeucine methyl ester hydrochloride
- Purity
- 95.0
- Packaging
- 1g
- Price
- $51
- Updated
- 2021/12/16
- Product number
- CS-B0437
- Product name
- Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
- Packaging
- 5g
- Price
- $69
- Updated
- 2021/12/16
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Chemical Properties,Usage,Production
Synthesis
67-56-1
52-52-8
60421-23-0
1. cool a suspension of 1-aminocyclopentanecarboxylic acid (675 g, 5.23 mol, 1.0 eq.) in methanol (6.5 L) at -15 °C using an ice/methanol bath. 2. thionyl chloride (687 mL, 9.4 mol, 1.8 eq.) was slowly added dropwise with controlled titration rate to maintain reaction temperature. 3. after completion of the dropwise addition, the cooling device was removed and the reaction mixture was allowed to warm to room temperature and stirred overnight. 4. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure. 5. 5. The concentrated residue was treated with dichloromethane (1 L) and concentrated again under reduced pressure to give methyl 1-aminocyclopentanecarboxylate hydrochloride as a white solid (938 g, 100% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (CD3OD) and NMR (DMSO-d6) to confirm the correct structure. 7. The product obtained did not require further purification and could be used directly in the subsequent reaction steps.
References
[1] Patent: US6353006, 2002, B1. Location in patent: Page column 31
[2] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 821-823
[3] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0449-0451
[4] Patent: WO2003/87069, 2003, A2. Location in patent: Page/Page column 103-104
[5] Patent: WO2006/44775, 2006, A2. Location in patent: Page/Page column 35-36
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride manufacturers
- Product
- Methyl 1-aminocyclopentanecarboxylate hydrochloride 60421-23-0
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 100KG
- Release date
- 2025-08-20
- Product
- Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride 60421-23-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- 1ton
- Release date
- 2019-12-18