ChemicalBook > CAS DataBase List > Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride

Product Name
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
CAS No.
60421-23-0
Chemical Name
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
Synonyms
Nsc161119;AC5C-OMe HCl;cycloeucinemethyl ester HCL;Cycloleucine Methyl EsteroHCl;CYCLOLEUCINE METHYL ESTER HCL;Cycloeucine methyl ester hydrochloride;Cycloleucine Methyl Ester Hydrochloride;METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL;methyl 1-aminocyclopentanecarboxylate, HCl;Methyl-1-aminocyclopentanecarboxylate hydrochloride
CBNumber
CB5201792
Molecular Formula
C7H14ClNO2
Formula Weight
179.64
MOL File
60421-23-0.mol
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Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Property

Melting point:
207-208 °C (decomp)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C7H13NO2/c1-10-6(9)7(8)4-2-3-5-7/h2-5,8H2,1H3
InChIKey
VLNNACMZTDZCFH-UHFFFAOYSA-N
SMILES
C1(N)(CCCC1)C(=O)OC
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Safety

HS Code 
2902190000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2351
Product name
Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
Purity
>98.0%(T)
Packaging
1g
Price
$39
Updated
2025/07/31
TCI Chemical
Product number
M2351
Product name
Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
Purity
>98.0%(T)
Packaging
5g
Price
$108
Updated
2025/07/31
TRC
Product number
M286653
Product name
Methyl 1-Aminocyclopentanecarboxylate Hydrochloride
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
076601
Product name
Cycloeucine methyl ester hydrochloride
Purity
95.0
Packaging
25g
Price
$378
Updated
2021/12/16
SynQuest Laboratories
Product number
4258-5-16
Product name
Methyl 1-aminocyclopentanecarboxylate hydrochloride
Packaging
5G
Price
$704
Updated
2021/12/16
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Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Chemical Properties,Usage,Production

Synthesis

67-56-1

52-52-8

60421-23-0

1. cool a suspension of 1-aminocyclopentanecarboxylic acid (675 g, 5.23 mol, 1.0 eq.) in methanol (6.5 L) at -15 °C using an ice/methanol bath. 2. thionyl chloride (687 mL, 9.4 mol, 1.8 eq.) was slowly added dropwise with controlled titration rate to maintain reaction temperature. 3. after completion of the dropwise addition, the cooling device was removed and the reaction mixture was allowed to warm to room temperature and stirred overnight. 4. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure. 5. 5. The concentrated residue was treated with dichloromethane (1 L) and concentrated again under reduced pressure to give methyl 1-aminocyclopentanecarboxylate hydrochloride as a white solid (938 g, 100% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (CD3OD) and NMR (DMSO-d6) to confirm the correct structure. 7. The product obtained did not require further purification and could be used directly in the subsequent reaction steps.

References

[1] Patent: US6353006, 2002, B1. Location in patent: Page column 31
[2] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 821-823
[3] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0449-0451
[4] Patent: WO2003/87069, 2003, A2. Location in patent: Page/Page column 103-104
[5] Patent: WO2006/44775, 2006, A2. Location in patent: Page/Page column 35-36

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Methyl 1-aminocyclopentanecarboxylate hydrochloride 60421-23-0
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99%min
Supply Ability
100KG
Release date
2025-08-20
Career Henan Chemical Co
Product
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride 60421-23-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%~99%
Supply Ability
1ton
Release date
2019-12-18

60421-23-0, Methyl 1-amino-1-cyclopentanecarboxylate hydrochlorideRelated Search:


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